This paper analyzes the document contents of targeted admission medical students in 16 provinces of China in 2016.Through analyses of the characteristics of the program, this study found that, 1) the number of admissions is determined by the national level and issued to the provincial level, where rural students are the main source of students, undergraduate program is the main enrollment category, and clinical medicine and traditional Chinese medicine are the main majors of admission;2) the number of admissions and the actual demand of health professionals of primary health care institutions do not match, the incubation period is too long, there is a shortage of targeted training model, contract signing is difficult to implement, and other problems.Therefore, in accordance with the problems, this paper suggests that, 1) the government should increase the number of admissions to match with the demands;2) a three-year bachelor's degree should be set up in order to shorten the incubation period;3) the training model of targeted admission medical students should be changed;and 4) various powerful measures should be carried out to attract and keep excellent health care professionals.

ObjectiveTo study the effect of responded hyperglycemia on the prognosis of acute stroke.Methods116 cases with acute stroke were divided into responded hyperglycemia group and normoglycemia group.The complications and activity of daily living(ADL) were compared in these two groups.ResultsResponded hyperglycemia severely influenced the recovery of patients as well as diabetes mellitus did.The incidence of infective complications in responded hyperglycemia group was higher than that of normoglycemia group.ConclusionsResponded hyperglycemia can make the prognosis of acute stroke bad.

OBJECTIVE:To explore the establishment of performance indicator system for evaluating national essential drug system in China.METHODS:Reference to the field of health policy performance evaluation research and practice at home and abroad.WHO indicators for evaluating national drug policies,and a qualitative study on the theory and approach of policy evaluation was conducted.RESULTS & CONCLUSION:To establish a China-specific performance evaluation indicator system,policy goals should be specified,and evaluation criterions and policy components should be also defined firstly.An indicator system framework of national essential drug system which based on WHO recommendatory indicators should be proposed accordingly.But detailed indicators should be established based on field research and experts counseling.

Objective Implement random sample from a simulation population,to evaluate the The impact of samplesize and sample-process on several usual importance evaluate methods,observe the stability of those methods.Methods This study introduced existed importance methods,using PROC SURVEYSELECT procedure to sample a fixed population for 1000 times,generating 1000 same size sample,to evaluate the stability of relative importance methods.We sampled the population to generate datasets with different sample size to observe impact of sample-size on those methods.Results The sum of squared correlation coefficients' estimator is bigger than model R-square,squared standardized regression coefficients' sum is smaller.In contrary,sum of the Product Measure,Relative Weight and Dominance Analysis are extremely close to model R-square.When the sample size small than 1000,the estimator have obviously variation,but the variation decreased when the sample size rise up.Conclusion The dominance analysis has best stability,also has the best match of model R2 in those methods.

BACKGROUND: The middle-school stage is the key period of personality figuring and taking shape.The mentation in this period is filled with a lot of special psychological contradictions and conflicts. Long-term psychological worry will affect the formation of perfect personality.OBJECTIVE: To understand the psychological health status in the middle-school students of Zhuang nationality and the main factors of influence.DESIGN: Randomized cluster sampling and questionnaire investigation based on middle-school students.SETTING: Department of Preventive Medicine, Youjiang Medical College of Nationalities.PARTICIPANTS: 2 000 middle-school students of 34 classes from 3 middle schools in Baise City and Longlin County were selected to attend the investigation with randomized cluster sampling method in November 2003.METHODS: The psychological health statuses of middle-school students were evaluated with symptom checklist (SCL).The list contained 90 items,including 9 factors of psychological symptom such as somatization,compulsion,sensitivity to human relations,anxiety,depression,hostility,dread,paranoia and psychosis.The grading system from 1 to 5 grades was used and the standard of the adult norm of the whole country was refered to:Factor score＜1.8 was normal;Factor score from 1.8 to 2.0 was mild abnormality;Factor score from 2.1 to 3.0 was moderate abnormality;Factor score＞3.0 was severe abnormality. Instructive words were unified.The investigative method and behavior were normalized.The questionnaires were filled in without recording the names and taken back from the spot and then compared with the norm of the whole country.MAIN OUTCOME MEASURES: The evaluated result of psychological health in middle-school students.RESULTS: 2 000 questionnaires were provided and 1 855 were valid after return with the effective rate 92.75%. ①The average scores of each factor of SCL were all higher in the middle-school students of Zhuang nationality than in the norm of the whole country. The significance of difference existed(P=0.000).②The scores of somatization,depression,anxiety,dread and psychosis were all higher in the schoolgirls than in the schoolboys.The significance of difference existed (P=0.000).③Except hostility factor,the scores of other factors were higher in the senior middle-school students than in the junior middle-school students.The difference was statistically significant(P=0.000).④The arranged sequences(from bigness to smallness) of each factor that affected psychological health of middle-school students of Zhuang nationality in Baise were depression,somatization,compulsion,anxiety,sensitivity to human relations,psychosis,paranoia,hostility and dread.The sensitivity to human relations ranked 4th and the anxiety ranked 6th in the schoolboys,but the orders of the 2 factors were just the opposite in the schoolgirls and the orders of other factors were the same in both the schoolboys and the schoolgirls.The first 3 factors all were:depression,somatization, compulsion.CONCLUNSION: The psychological health status was lower in the middle-school students of Zhuang nationality than in the norm of the whole country and the first 3 factors that affected their psychological health were:depression,somatization and compulsion. The levels of psychological health on somatization,depression,anxiety,dread and psychosis were lower in the schoolgirls than in the schoolboys. The psychological problems were more serious in the senior middle-school students than in the junior middleschool students. The levels of psychological health in middle-school students of Zhuang nationality were relatively lower and the psychological education and intervention study should be provided aiming at psychological characteristics of different population.

OBJECTIVE:To provide references for the establishment of performance indicator system for evaluating National essential medicines system in China. METHODS:To analyze the theory and approach of policy evaluation and WHO indicators for evaluating national drug policies. A literature study on relevant information was conducted. RESULTS & CONCLUSION:China may refer to WHO framework for the evaluation index system,according to the target of various stages of essential drugs system,in the implementation of our system of essential medicines on the basis of a full investigation,combined with our medical and health background and status,build essential drugs system of performance appraisal system and performance indicators.

Objective: To investigate the cytotoxicity of ICE gene transfection in Combination with Antitumor Chemicals killing Hepatocellular Carcinoma Cells in vitro.Methods: The recombinant plasmid pLXSN-hICE was transferred to virus packing cell PA317 by electroporation method. And then the retrovirus containing human ICE cDNA generated by these PA317 cells were used to transfect human hepatocellular carcinoma cell line HepG2. The apoptosis of transferred cells were examined by gel electrophoresis. The influence of chemotherapeutic drug Carbo-platin to the proliferation of hepatocellular carcinoma cell line SMMC7721 and its derivative cells(SMMC7721-hICE,SMMC7721-antisence hICE,SMMC7721-neo)was observed by incorporation of 3H-TDR. Results: Electrophoresis of DNA displayed the apoptosis ladder of HepG2 transfected by ICE gene. The proliferation of SMMC7721-hICE was significantly suppressed in vitro induced by Carbo-alatin compared to the other three cell lines. Conclusion: ICE gene transfection could greatly increase the susceptibility of SMMC7721 cells to apoptotic cell death following chemotherapy. These findings suggest that combining ICE gene transfection with utilizing antitumor drugs would represent a novel approach for the effective treatment of hepatocellular carcinoma.

Based on the anatomical study of kidney in mammals of 27 families and 163 species, the authors discovered Anoa depressicornis type kidney, and obtained the evidence of morphological transition between Ox-type kidney and Pig-type kidney. After observing the renal papillary structure of Budorcas taxicolor, the evidence of fact and theoretical bases of the biological view was proved that the general papillae are developed from the multi-papillae kidney. The author advanced a new type of leaf-shaped multipapillae kidney. The authors suggest to classify the mammalian kidneys principally into 2 groups, i. e, simple and composite kidney, and subdivide them into 4 types, i. e, multipapillae and concentrated papillae for simple kidney and leaf-shaped multipapillae and ball-shaped mono-papillae for composite kidney. In contrast to the previous classification, the 2-group 4-type classification recommended here with its solid anatomical foundation is conformable with the viewpoint of biology, and is more practical and integrated.

Objective To search and evaluate the quality of reports of clinical trial studies published in Chinese Pediatric Emergency Medicine according to CONSORT statement.Methods We collected all articles published in Chinese Pediatric Emergency Medicine from January 1,2011 to November 31,2015 through searching the WanFang Database,then evaluated and analyzed clinical trial studies.Results Among all 1317 articles we retrieved,62 (4.7％)of them belong to clinical trial study.According to CONSORT statement,all the articles satisfied items from 1b to 6b (including abstract,introduction,trial design,participants,interventions and outcomes),only 30(48.4％) and 4(6.5％) articles mentioned item 8a (method used to generate the random allocation sequence)and 8b(type of randomization;details of any restriction),respectively.None of the editors reported item 9(mechanism used to implement the random allocation sequence,describing any steps taken to conceal the sequence until interventions were assigned)and 10(who generated the random allocation sequence,who enrolled participants,and who assigned participants to interventions).Among 62 included studies,33(53.2％)studies concentrated on respiratory system diseases.However,studies about nervous system,circulatory system and digestive system were 5(8.1％),4(6.5％)and 4 (6.5％) respectively.Although all the results had statistical significance,only 38(61.3％),7(11.3％) and 5 (8.1％)mentioned randomization,follow-up and blinding respectively.Flow diagram was only included in one (1.6％) article.Conclusion The articles of clinical trial studies published in Chinese Pediatric Emergency Medicine did not take CONSORT statement as reference completely.

ObjectiveTo check the isolated heart by coronary angiography to discover the location, na-ture and degree of the coronary artery lesions more accurately and increase the comprehensive evaluation ability of cardiovascular disease.MethodsTen fresh isolated hearts with different causes of death were extracted and injected with barium sulphate as contrast substance by ring injector, then developed under Xper FD20 angiography equipment. The obtained pictures and image data were handled by three-dimen-sional angiography images with the software attached to the angiography equipment. The coronary artery tissues were HE stained and observed by microscope. The HE staining results were compared with the angiographic results.ResultsThe imaging data obtained from the 10 cases for examination showed 8 cases without coronary artery stenosis and 2 cases with Ⅲ, Ⅳcoronary artery stenosis, which were consistent with HE staining results of coronary artery organization and the both results were confirmed. ConclusionIsolated coronary angiography has an unique advantage for accurate grading of classification of coronary artery stenosis, examination of vascular malformation and tiny lesions, which can provide reference for the localization of small lesions and basis during the autopsy for identification conclusion.