Objective:To explore the efficacy of gamma globulin at different doses combined with dexamethasone in the treatment of children with severe idiopathic thrombocytopenic purpura. Methods: Totally 96 cases of patients with idiopathic thrombocytopenic purpura were divided into group A ( standard high dose of gamma globulin+dexamethasone) , group B ( middle dose of gamma globulin+dexamethasone) and the control group ( dexamethasone) . The clinical effects and platelet parameters of the three groups were com-pared. Results:The levels of PLT, PCT and PDW in group A and group B after the treatment were higher than those in the control group(P<0. 05). The recovery time of normal platelet and the stop time of bleeding in group A and group B were lower than those in the control group(P<0. 05), and there was no significant difference between group A and group B(P>0. 05). The clinical effective rate of group A and group B was higher than that in the control group(P<0. 05), and there was no significant difference between group A and group B(P>0.05). There was no significant difference in the incidence of adverse reactions among the three groups (P>0. 05). Conclusion:Gamma globulin at middle dose shows significant effect as at high dose in the patients with ITP, which can reduce the dosage and is worthy of clinical promotion.

Objective To explore the clinical nursing effect of the atomization inhalation therapy on pediatric asthmatic suffocating pneumonia .Methods Ninety-three patients with pediatric asthmatic suffocating pneumonia were chosen and randomly divided into the observation group ( n=47 ) and the control group ( n=46).The control group received the routine treatment (controlling infection through antibiotics , keeping calm and reducing of asthma , relieving cough and sputum , etc.) and conventional nursing measures ( health education, diet nursing, psychological nursing, etc.), and the observation group received the atomization inhalation therapy on the basis of the control group .The nursing and therapeutic effects were compared between the two groups .Results The total effective rate of treatment was 93 .6%( 44/47 ) in the observation group , which was higher than 67.4%( 31/46 ) in the control group , and the difference was statistically significant (χ2 =10.244, P<0.05).The average time of the disappear of asthma and moist rales and the hospital stay were (6.4 ±1.5), (7.0 ±1.7), (8.1 ±2.1) d in the observation group, which were shorter than (9.1 ± 1.4), (10.2 ±2.0), (10.9 ±1.9) d in the control group, and the differences were statistically significant (t=10.541, 13.293, 10.941, respectively; P <0.01).Conclusions Application of the atomization inhalation therapy on pediatric asthmatic suffocating pneumonia based on the routine treatment and nursing can effectively improve the therapeutic effect , relieve the pain of patients and promote the rehabilitation of patients .