1.Antitussive, Antiasthmatic, Antiinflammatory and Diuretic Effects of Herba Ephedrae Cultivated Artificially in Gansu Province
Bin GE ; Qiaoming WANG ; Aixia XU ; Jianxin ZHANG
China Pharmacy 1991;0(05):-
OBJECTIVE: To study the antitussive, antiasthmtic, anti-inflammatory and diuretic effects of Herba Ephedrae cultivated artificially in Gansu province and to compare which with the wild Herba Ephedrae. METHODS: Each pharmacological action index was determined by concentrated ammonia method, windpipe capacity method, pinna swelling method and metabolic cage method. RESULTS: Both of the two kinds of Herba Ephedrae could reduce the cough responses of mice, resist the spasmodic contraction of the tracheal smooth muscles, reduce the swelling of auricle of mice and increase urine volume of rats. CONCLUSIONS: Herba Ephedrae cultivated artificially in Gansu province are equivalent to the wild one in terms of the antitussive, antiasthmtic, anti-inflammatory and diuretic effects thus it can serve as a substitute for the wild one.
2.Clinical characteristics and prognostic factors of primary gastric lymphoma
Min ZHAI ; Haitao ZHANG ; Yunliang WANG ; Fei WANG ; Xiaogang ZHOU ; Qiaoming ZHI ; Jin ZHOU
Chinese Journal of General Surgery 2018;33(3):232-234
Objective To explore the clinical characteristics and prognostic factors of primary gastric lymphoma.Methods Clinical data of 78 primary gastric lymphoma patients treated between September 2012 and January 2017 in our hospital were analyzed retrospectively.Results 1-year and 3-year survival rate were 86% and 68% respectively.Univariate analysis showed that the four factors including the level of serum lactate dehydrogenase (x2 =35.088,P =0.000),Musshoff stage (x2 =29.930,P =0.000),pathology types (x2 =6.077,P =0.014),IPI score (x2 =21.337,P =0.000) were associated with the prognosis.Multivariate analysis showed that Musshoff stage was an independent risk factor for the prognosis when stage Ⅰ,stage Ⅱ (OR =1.075,95% CI:0.060-19.107,P =0.961) were compared with stageⅢ (OR =11.994,95% CI:1.042-138.083,P =0.046),or stage Ⅳ (OR =13.165,95% CI:1.476-117.417,P =0.021).Conclusions Musshoff stage is an independent factor for the prognosis,surgical treatment can not prolong survival and chemotherapy is the therapy of choice.