1.Determination of Plant Hormones by Capillary Electrophoresis Based on Polymer Micelles
Xiadi CHEN ; Qiaomei LU ; Jintian CHENG ; Lan ZHANG
Chinese Journal of Analytical Chemistry 2015;(1):127-131
With the increasing number of food safety problems caused by the abusing and misusing of plant hormones, it will be increasingly important to strengthen the trace detection of plant hormones in foods. In this study, benzyl methacrylate_methyl methacrylate_based amphiphilic polymer micelles were prepared, and a method for trace determination of five plant hormones was established by using these micelles. This method was rapid, sensitive and reproducible. Through optimization, the best experimental conditions were obtained as follows: 2 g/L polymer micelles, 50 mmol/L NaOH_H3BO3 buffer (pH 9. 2), 15 kV running voltage. Based on this novel method, naphthalene acetic acid in the solution of rooting powder was determined.
2.Effect of Ivabradine Prolonging the Cardiac Action Potential Duration With its Proarrhythmic Action in Experimental Rabbitin vitro
Qiaomei YANG ; Yuzhi LIANG ; Wei YANG ; Yansheng DING ; Lu REN ; Sihui HUANG ; Xiaohong WEI ; Lin WU
Chinese Circulation Journal 2015;(6):585-589
Objective: To observe the effect of ivabradine (IVA) on atrial and ventricular monophasic action potential duration (MAPD) and its proarrhythmic action at presence of sea anemone toxin-II (ATX-II) in isolated rabbit heart modelin vitro. Methods: The perfusion of isolated heart from female New Zealand white rabbit was conducted by Langendorff method in vitro. Left atrial and left ventricular endo- , epi-cardial action potential were recorded when pacing with ifxed frequency of 350 ms (in correspondence with the heart rate of 171 times/min) to observe the effect of IVA alone and ATX-II (3 nmol/L) with IVA on MAPD90. In addition, to observe the action of IVA alone and ATX-II with IVA on proarrhythmia when IVA reducing the heart rate to autonomous cardiac rhythm as (156±10) times/min. Results: IVA at (3-10) μmol/L prolonged atrial and ventricular endo- , epi-cardial MAPD90 by (15.9 ± 2.0) ms, (31.5 ± 4.0) ms and (23.9 ± 3.0) ms (n=6,P<0.01), respectively. ATX-II at 3 nmol/L prolonged atrial and ventricular MAPD90 by (36.5 ± 5.0)ms and (19.9 ± 3.0) ms, (19.5 ± 4.0) ms (n=6,P<0.01) respectively. With ATX-II treatment, IVA at (6-10) μmol/L decreased atrial MAPD90 by (14.4 ± 4.0) ms (n=6,P<0.01), it induced atrial arrhythmia. With 3 nmol/L of ATX-II treated ventricle, IVA at (3-10) μmol/L obviously prolonged endo- and epi-cardial MAPD90 by (36.2 ± 7.0) ms and (27.5 ± 5.0) ms(n=6,P<0.01), respectively. IVA didn’t increase ventricular beat-to-beat variability and transmural dispersion of MAPD90 no matter with or without ATX-II treatment, no ventricular arrhythmia occurred. Conclusion: IVA prolongs both atrial and ventricular MAPD, with increased late sodium current, IVA may induce atrial arrhythmia but not ventricular arrhythmia in experimental rabbits in vitro.
3.Application of Workshop in Functional Rehabilitation of Affected Limb for Postoperative Breast Cancer Patients
Yin XU ; Zheng ZHOU ; Qiaomei FU ; Yao LU ; Ping DU ; Li LIU
Chinese Journal of Rehabilitation Theory and Practice 2017;23(4):481-484
Objective To explore the effect of workshop on postoperative function of affected limb in patients with breast cancer. Meth-ods From August, 2015 to June, 2016, 70 patients with breast cancer after modified radical mastectomy were randomly divided into control group (n=35) and observation group (n=35). The control group was instructed by the primary nurse bedside based on the traditional method, while the observation group was guided with workshop mode. Results Ten days and one month after surgery, the range of motion of the shoulder joint in the observation group was superior to the control group (t>2.030, P<0.01);the incidence of lymphedema of the affected limb in the observation group was lower than that in the control group (u=2.195, P<0.05). Conclusion Functional exercise guided with work-shop mode could improve postoperative function of affected limb in patients with breast cancer.
4.Effects of narrative nursing on posttraumatic growth for patients with amputation
Qianjiao ZENG ; Chaoran CHEN ; Dongmiao LIU ; Shan HAN ; Jingjing LU ; Qiaomei CHENG
Chinese Journal of Practical Nursing 2019;35(8):611-615
0bjective To explore the effects of narrative nursing on posttraumatic growth for patients with amputation. Methods From December 2016 to March 2018,a total of 62 hospitalized patients with amputation were randomly assigned into the control group and the intervention group by random number table.The control group received routine nursing,the intervention group received narrative nursing on the basis of control group.Two groups were evaluated by Posttraumatic Growth Inventory(PTGI) before and after intervention. Results Before intervention,the scores of reflections on life, personal strengths, new possibilities, relating to others, self-transformation and posttraumatic growth in the the control group were (19.87 ± 5.22), (7.90 ± 2.53), (8.83 ± 3.62), (9.73 ± 3.13), (10.63 ± 3.01), (56.97 ± 17.21) points, respectively. After intervention,the scores were (20.80±5.89), (8.80±2.17), (8.90±3.39), (10.27± 2.75), (11.07 ± 3.12), (59.83 ± 16.91) points, respectively, except new possibilities, the scores of each dimension and total scores of posttraumatic growth in the the control group were higher than before,the differences were statistically significant(t=3.00- 5.34, P<0.05).Before intervention,the scores of reflections on life, personal strengths, new possibilities, relating to others, self-transformation and posttraumatic growth in the the intervention group were (20.28±4.94), (8.17±2.58), (8.59±3.48), (9.55± 2.90), (11.07±2.83), (57.66±16.42) points, respectively. After intervention, the scores were (23.79±4.70), (10.10±2.17), (10.72±3.34), (11.69±2.22), (12.79±3.28),(69.10±14.92) points, respectively, the scores of each dimension and total scores of posttraumatic growth in the intervention group were statistically higher than those in the control group and before intervention,the differences were statistically significant (t=10.61-16.75, P<0.05). Conclusion Narrative nursing can effectively improve the level of posttraumatic growth and psychological state for patients with amputation.
5.AppLication effects of respiratory training in patients with dysphagia: a systematic review
Fang WAN ; Lu CHEN ; Zhiqing YAO ; Qiaomei FU
Chinese Journal of Modern Nursing 2019;25(7):844-848
Objective? To systematicaLLy review the respiratory training on swaLLowing function and respiratory function among patients with dysphagia so as to provide a reference for rehabiLitation nursing of patients with dysphagia. Methods? From estabLishing the database to 30th ApriL 2018, we retrieved the randomized controLLed triaLs (RCTs) on respiratory training of patients with dysphagia in PubMed, EMBASE, Web of Science, Cochrane CentraL Register of ControLLed TriaLs, CINAHL, Physiotherapy Evidence Database, Chinese BioMedicaL Literature Database (CBM), China NationaL KnowLedge Infrastructure (CNKI) and WanFang Data by computer. The Literatures were screened and quaLity of the incLuded Literatures were evaLuated according to the system evaLuation method of the Cochrane coLLaboration. The RevMan5.3 was used to statisticaL anaLysis. ResuLts? A totaL of 9 Literatures were incLuded, and three of them were with the LeveL A of Literature quaLity and the rest were with the LeveL B. Meta-anaLysis showed that compared with routine dysphagia nursing, respiratory training couLd improve the swaLLowing function evaLuated by water swaLLow test [RR=1.33, 95%CI (1.17, 1.53), P< 0.01], forced vitaL capacity (FVC) [MD =0.47, 95%CI(0.11, 0.82), P< 0.01], forced expiratory voLume in one second (FEV1) [MD=0.47, 95%CI(0.20,0.74), P<0.01], peak expiration fLow (PEF) [MD=1.00, 95%CI(0.91, 1.10), P<0.01]and reduce the score of penetration-aspiration scaLe (PAS) [MD=-1.05, 95%CI (-1.70, -0.41), P< 0.01]of patients with dysphagia. ConcLusions? Compared with routine dysphagia nursing, respiratory training couLd improve the swaLLowing function evaLuated by water swaLLow test, FVC, FEV1, PEF and reduce the score of PAS of patients with dysphagia. However, the findings stiLL need be vaLidated by Large sampLe, muLticenter and high quaLity RCTs.
6.Effects of "internet +" nursing intervention model on rehabilitation outcomes in stroke patients: a Meta-analysis
Lixinbei SHENG ; Lu CHEN ; Qiaomei FU ; Yan CHEN
Chinese Journal of Modern Nursing 2020;26(6):764-768
Objective:To systematically assess the effects of "internet +" nursing intervention model on rehabilitation outcomes in stroke patients so as to provide an evidence-based basis for clinical nurses to carry out "internet +" nursing service new model in stroke patients.Methods:Randomized controlled trials (RCTs) related on effects of "internet +" nursing intervention model on rehabilitation outcomes in stroke patients were retrieved in China Biological Medicine (CBM) , Chinese National Knowledge Infrastructure (CNKI) , WanFang Data, PubMed, Embase, Cochrane Central Register of Controlled Trials by computer from building database to May 2019. RevMan 5.3 was used to the systematic review for literatures meth the inclusion criteria.Results:A total of six literatures were included involving 637 samples. Systematic review showed that "internet +" nursing intervention model could improve the motor function [ MD=13.87, 95% CI (7.93, 19.81) , Z=4.57, P<0.01]and activity of daily living [ MD=14.43, 95% CI (6.15, 22.71) , Z=3.41, P<0.01]of stroke patients during rehabilitation. Conclusions:"Internet +" nursing intervention model provides a good channel for rehabilitation and health education for stroke patients after going back to family and community, helps stroke patients to improve motor function during rehabilitation and activity of daily living, but that still exhibits the problems needed to be perfected and solved by medical staff exerting themselves.
7.Effects of Home FaLL Hazards Assessment on preventing faLLs in patients receiving hip arthropLasty
Jiayan XU ; Xinhua LI ; Xiaobei WENG ; Li DING ; Yuanyuan LU ; LingLi ZHANG ; Qian DING ; Wen QIN ; Qiaomei FU
Chinese Journal of Modern Nursing 2019;25(7):888-892
Objective? To expLore the effects of Home FaLL Hazards Assessment (HFHA) on the incidence rate of home faLLs and recovery of hip function in patients receiving totaL hip arthropLasty (THA). Methods? TotaLLy 423 patients who received uniLateraL THA for the first time in the Department of Orthopedics, Nanjing Drum Tower HospitaL admitted from JuLy 2015 to JuLy 2017 were seLected by convenient sampLing and divided into the controL group (n=203) and the treatment group (n=220). Patients in the controL group received conventionaL postoperative nursing care and discharge guidance, whiLe the home faLL hazards of patients in the treatment group were evaLuated by HFHA in addition to conventionaL postoperative nursing care and discharge guidance. Nursing care was provided to them based on the assessment resuLts. The joint function score at discharge and 3 months after discharge, the incidence rate of faLLs over the past one year and the severity of injury caused by faLLs were compared between the two groups. ResuLts? There was no statisticaL difference in Harris index and BartheL index scores between the two groups at discharge (P> 0.05). Harris index and BartheL index scores 3 months after discharge were statisticaL differences in both groups (P<0.05). 55 faLLs occurred over the past one year in the controL group, 7 of them with moderate or above injuries, whiLe 35 faLLs occurred over the past one year in the treatment group, 1 of them with moderate or above injuries. There were statisticaL differences in the incidence rate of faLLs and injury degrees between the two groups (P<0.05). ConcLusions? HFHA, when used to assess the home faLL hazards, enabLes THA patients to know and note the high-risk hazards contributing to faLLs in their environment of rehabiLitation and effectiveLy reduces the patients home faLLs by improving the home environment.