Objective To construct nursing needs scale for school-age children with acute leukemia (AL) during lumbar puncture by using Delphi technique.Methods A certain number of experts were chosen for consulting to form a consulting scale.Two-round consultations were conducted and the results were analyzed.Results The effective response rate of the experts' questionnaire for 2 rounds was 100％ (17/17).The specialist group authority coefficient was 0.85.The coordination coefficients for 2 rounds were 0.437 and 0.516 respectively (P ＜ 0.01).The nursing needs scale for school-age children with AL during lumbar puncture comprised of 5 first-level indicators and 30 second-level indicators.Conclusions This scale can scientifically and quickly evaluate the nursing needs of school-age children with AL during lumbar puncture,it provides a research tool to develop individualized interventions with demand as the direction.

Objective To investigate the effect of bowel preparation before colonoscopy and its influencing factors. Methods A total of 283 patients with colonoscopy were recruited by convenience sampling method. They were investigated with basic information questionnaire of bowel preparation and their intestinal cleanliness were assessed by the Ottawa Assessment Scale. The status of bowel preparation and it′s influenced factors were analyzed. Results The total score of Ottawa Assessment Scale was (5.37 ± 2.22) points, and the efficiency of intestinal cleaning was only 59%(167/283). Logistic regression analysis showed that age (OR=1.033, P=0.013); history of chronic constipation (OR=10.341, P=0.000);history of appendectomy (OR=5.349, P=0.007); walking time during medication (OR=0.350, P=0.000);incomplete intake of the preparation (OR=0.078, P=0.000), the time interval between the initiation of ingestion and the onset of bowel activity (OR=1.034, P=0.000), defecation frequency (OR =0.794, P=0.004);characteristics of last stool (OR=0.159, P=0.000) were influencing factors of intestinal cleanliness. Conclusions The intestinal cleanliness of patients with colonoscopy is still at a low level. In the future, medical personnel should identify patients with risk factors early, and give them specific bowel preparation, so as to improve the quality of bowel preparation effectively.

Objective To construct the key-point guidelines of bowel preparation for elderly patients with colonoscopy. Methods The guidelines were made based on literature review,theoretical analysis,qualitative interview.Then they were determined by 14 clinical nurse specialists, nursing education experts and medical experts from 6 provinces or cities through two rounds of expert consultations. Results The response rate of two rounds'questionnaire was 100.00%. The authority of experts coefficient in the two rounds were 0.89. The coefficients of variation of the first and second rounds were respectively 0.07~0.27 and 0.05~0.13. The coordination coefficients for the 2 rounds were 0.377 and 0.404 respectively (Χ2=105.473 and 124.307,P<0.001).In the first round,the average of the importance rating was 3.50~4.95, with a standard deviation of 0.35~0.95.In the second round,the average of the importance rating was 4.71~4.93,with a standard deviation of 0.27~0.61.The key-point guidelines of bowel preparation included 3 key points for bowel preparation, 4 key moments,7 key guidance contents, 4 criteria for the process of bowel preparation and the corresponding remedial measures. Conclusion This study established the key-point guidelines of bowel preparation for elderly patientsand the degree of enthusiasm,authority,coordination and concentration of the experts was high so as to provide a reference for the clinical implementation of standardized bowel preparation guidance.

Objective To explore the factors affecting non-compliance in bowel preparation for patients undergoing colonoscopy and to provide evidence for improving patients' compliance. Methods Guided by the phenomenological research method, semi-structured interviews were performed among 16 patients who had poor bowel preparation for colonoscopy at the digestive endoscopy center in 3 Class Ⅲ Grade A hospitals in Suzhou from January to April 2017. The data were analyzed by Colaizzi analysis method. Results Through the interviews, the factors influencing bowel preparation compliance were summed up into 3 themes: the neglect of the importance of strict compliance with bowel preparation, the inability to tolerate bowel preparation, and lack of specialized knowledge of bowel preparation. Conclusions To improve the compliance of bowel preparation for patients undergoing colonoscopy, medical staff should correctly guide the patients to understand the importance of bowel preparation and ensure the full grasp of the specific requirements, on the other hand, should actively strive to improve the patient's tolerance of bowel preparation.

Objective To explore the relationship between renal volume and function in the preterm and term newborns at different gestational ages.Methods This study was conducted at the First Affiliated Hospital of Zhengzhou University from October 2016 to March 2018.A total of 626 newborns with different gestational ages were included and the renal volume was determined by ultrasonography.Blood samples were taken for laboratory tests to detect renal function including urea,creatinine,uric acid and estimated glomerular filtration rate.Results A total of 352 preterm and 274 full term newborns were enrolled at birth.The mean gestational age of the neonates was (36.0 ± 3.5) weeks and the mean birth weight was (2.59 ±0.77) kg.The mean renal volume of the preterm infants was (19.57 ±4.30) cm3 and estimated glomerular filtration was (21.68 ± 5.99) mL/(min · 1.73 m2);the mean renal volume of the term infants was(23.03 ± 3.80) cm3 and estimated glomerular filtration was(46.60 ± 10.21) mL/(min · 1.73 m2).The renal volume and estimated glomerular filtration of term infants was significantly greater compared to the preterm infants (t =12.96,33.10,all P ＜ 0.001).The renal volume was highly linear positively correlated with gestational age,birth weight and birth length (r =0.546,0.605,0.592,all P ＜ 0.001).The renal volume was highly linear positively correlated with estimated glomerular filtration(r =0.396,P ＜ 0.001).The renal volume was negatively correlated with urea,creatinine and uric acid(r =-0.210,-0.280,-0.176,all P ＜ 0.001).Conclusions The renal volume increases with gestational age and birth weight in neonates.Estimated glomerular filtration increases with renal volume in neonates.The preterm infants have immaturity kidney size and poor development so that they need special medical care.

This review has summarized the methods and contents of nursing interventions about bowel preparation before colonoscopy. The specific intervention strategies expounded from four aspects, which included dietary intervention, psychological intervention, drug intervention and exercise intervention. The form and effect evaluation of interventions also were summarized. This review expects to provide evidence-based basis for clinical interventions in the future.

Objective To investigate the parents′ requirement of children with acute leukemia during the period of lumbar puncture. Methods A total of 105 parents of children with acute leukemia during the period of lumbar puncture were selected by purposive sampling to complete the questionnaire. Results The total of requirements was 3. 53, in which the top three were ensuring the children safe and comfortable (3. 92 ± 0. 54) score, the information acquisition (3. 79 ± 0. 65) score and receiving support and help (3. 68 ± 0. 71 ) score. The parents had different specific care requirements before and after lumbar puncture. Conclusions Doctors and nurses should pay more attention to the needs of parents, and actively take corresponding measures to meet their different requirements so as to help children to cooperate with lumbar puncture and prevent complications.

This review has summarized the methods and contents of nursing interventions of lumbar puncture in children.The specific intervention strategies have been expounded from four aspects,including supportive psychotherapy,cognitive behavior intervention,music therapy intervention and comprehensive nursing intervention.The evaluations of intervention effects have been summarized and put forward the research shortcomings in current domestic and international research.We should pay attention to the need of children undergoing lunber puncture.This review has pointed out the direction of further research in the future.

Objective:To explore the correlation between the index of hemodynamics in perinatal period and retinopathy of prematurity(ROP), so as to provide basis for the better prevention and treatment of ROP.Methods:From May 2017 to April 2019, the preterm infants were admitted to the Neonatal Intensive Care Unit of the First Affiliated Hospital of Zhengzhou University at birth and were hospitalized for more than 2 weeks, gestational age ≤ 35 weeks and birth weight ≤ 2 500 g. They were selected as the study objects.The perinatal data including heart rate, blood pressure, patent ductus arteriosus, ventricular septal defect, and NT-proBNP level on the 1 st, 7 th and 14 th day, respectively after birth were collected.They were divided into ROP group and non ROP group according to the results of the retinopathy screening report.The influencing factors of ROP were screened out by univariate analysis and multivariate regression analysis. Results:A total of 1 119 subjects were included, 105 infants with ROP were detected, and the prevalence of ROP was 9.4%.Among them, 12 cases of pre-threshold lesion type 1 and threshold lesions required treatment, accoun-ting for 1.07% of screened preterm infants .Univariate analysis and multivariate regression analysis revealed that gestational age, birth weight, total oxygen therapy time, and intrauterine growth restriction were all factors affecting ROP, and 2 hemodynamic related indicators, such as the level of NT-proBNP in plasma on the 14 th day after birth, and placenta previa or abruption were also related to ROP( OR=0.604, 0.647, 1.276, 2.361, 1.688 and 2.506, respectively, all P<0.05). Conclusion:The hemodynamic changes in perinatal period may be involved in the formation of ROP, and it is necessary to further clarify its mechanism.