Objective: To study the expression of bone morphogenetic protein (BMP)-2 during midfacial sutural distraction osteogenesis in dogs and to probe the mechanism of sutural distraction osteogenesis. Methods: Eighteen mongrel dogs (12-week old) were randomly divided into distraction osteogenesis group(n = 12) and the control group(n = 6). Rigid external distractor was used for sutural distraction of the midfacial skeleton in the experimental animals. Two experimental and one control dogs were sacrificed at defined time points (on the 5th,10th and 15th day of distraction, the 10th and 20th day of fixation, and 30th day after completion of fixation). The expression of BMP-2 was observed by means of immunohistochemistry. Results: During the period of distraction and fixation, positive staining of BMP-2 was found in the proliferated preosteoblasts, the mesenchymal cells and the newly formed bone matrix at the sutural margin of the experimental dogs; weak expression was also noticed in the control dogs. Compared with that in the control group, the expression of BMP-2 in the experimental group increased and reached the peak on the 15th of distraction, then gradually decreased, the expression of BMP-2 nearly restored to the normal level 1 month after the removal of the distractor. Conclusion: The mechanical strain can lead to the generation of endogenous BMP-2, which may play an important role in the new bone formation.

Objective To explore the predicting role of organism weak magnetic field analytic technology on heart functions in individuals with normal electrocardiogram(ECG).MethodsA total of 1534 subjects who receired health examinations and organism weak magnetic field tests in Health Science Center of Chinese PLA General Hospital from May to June 2009 were enrolled.Positive rates of organism weak magnetic field analytic technology,echocardiography,and myocardium enzyme test for heart dysfunction among populations with hypertension,hyperglycemia and hyperlipidemia were compared.Statistical analysis was carried out to detect if there was close correlation between different heart risk and the weak magnetic field index.Results(1)The positive rate of the organism weak magnetic field analytic technology for heart dysfunction among subjects with normal ECG was 96.0%(1472/1534),which was significantly higher than echocardiography(27.5%,200/726)and myocardium enzyme testing(6.9%,106/1532).The positive rate of organism weak magnetic field analytic technology was increased with the seriousness of hypertension ,hypergjycemia and hyperlipidemia(P＜0.05＝.(2)Different heart risks showed close correlation with heart meridian and potassium(P＜0.05＝.Conclusion The prediction of organism weak magnetic field analytic technology on potential heart dysfunction(as a result fromhypertension,hylperglycemia and hyporlipidemia)in individuals with normal ECG is highly sensitive andrelatively objective.

Objective To explore predictive effects of organism weak magnetic field analytic technology on heart diseases among adults with hypertension,hyperglycemia and hyperlipidemia.Method A total of 1534 individuals who received health examinations and organism weak magnetic field tests in Health Science Center of Chinese PLA General Hospital from May to June 2009 were enrolled.Statistical analysis were carried out to detect if the heart function index of organism weak magnetic field tests could identify different conditon for the incident dysfunction of heart in low-,potential-,high-risk groups classified by the three high agent using the nonparametric test.High-dangerous three-high groups include simple,compound,additional and assembling sorts of combining types.Results The quantitative values of heart meridian of one potential-risk and nine high-risk three-high groups differs evidently from the low-risk high-risk three-high groups by Moses test(P ＜ 0.05).There was statistically significant difference of the quantitative values of heart meridian,potassium,magnesium,manganese,cardiovascular,circulaton,heart endocrine,and T2 among the low-,potential-and high-risk levels and other different types of three-high groups by Wilcoxon rank sum test(P ＜ 0.05).Conclusion Organism weak magnetic field analytic technology could reveal change of heart dysfunction in individuals with normal electrocardiogram.

Ketamine is mighty and short effective antalgic, advantaged in shock, asthma, etc. but it is restricted clinically because of serious side-effect. Today, low-dose ketamine(≤1 mg/kg) combined with opiates can enhance the efficacy of the opiates so that the dose of the opiates decrease relatively. The ketamine-opiates solution has enough stability and respiratory problems don't appear. So it is feasible that the combination of the two medicines can be used for patients with cervical spinal cord injury, who are susceptive to the respiratory distress and especially for the patients with depression.

Objective To constitute a database of chronic wounds for characterizing the patients with chronic wounds.Methods Based on the guideline of chronic wounds defined by international wound healing society,86 outpatients with chronic wounds were selected between January and October in 2013 to set up a wound database using the wound information management system.The parameters including etiology,age distribution,mean time of fracture healing and wound healing time posterior to different treatments were analyzed.Results (1) Statistical difference existed for cause distribution (P ＜0.05).Top three causes were trauma (29％),varicosity (26％) and pressure sore (19％).(2) Age distribution varied significantly among the patients with various causes of chronic wounds (P ＜ 0.05).(3) Statistical difference was observed in healing time of various types of chronic wounds (P ＜ 0.05).Diabetic wound and varicose ulcer took the longest healing time,with average 116.36 days and 88.48 days respectively.(4) Patients treated with novel dressings had shorter healing time than those managed with traditional dressings (P ＜ 0.05).Conclusions Trauma,varicosity and pressure ulcer are relatively common among the outpatients.Etiology of chronic wounds is strongly related to age and novel dressings contributed to a shortened cause of the disorder.

This paper reports the study and design of a visualization system of the ultrasonic rhinitis therapeutic apparatus with the function of endoscopic sinus. On Linux operating platform, we captured the video data of a video capture card that connected the endoscopic sinus using Video4Linux (V4L2) that was provided by the operating system. The video images were displayed by Qt. The visualization system solved the problem that the current ultrasonic rhinitis therapeutic apparatus had to rely on the large and expensive endoscopy equipment. And this simplified the doctors' operation, met the need of monitoring nasal cavity in the process of operating, greatly reduced the costs of treatment and would contribute to the promotion of the instrument. As a result, it has been tested that the nasal endoscopic image achieved by the system is clear and smooth, and fully meet the clinical needs of ultrasonic treatment of rhinitis.
Endoscopy ; Equipment Design ; Humans ; Nasal Cavity ; surgery ; Rhinitis ; therapy ; Software ; Ultrasonics ; instrumentation ; Video Recording

The incidence rate of erectile dysfunction (ED) is reportedly as high as 30-90% after radical prostatectomy for prostate cancer, which seriously affects the patients' quality of life. Penile rehabilitation is defined as the use of any drug or device at or after radical prostatectomy to maximize erectile function recovery. A variety of treatment options are available for post-prostatectomy ED patients, including oral phosphodiesterase 5 inhibitors (PDE5I) , intracorporal injections, vacuum erection device, and penile prosthesis. This article presents an overview of the currently used methods for the drug treatment and penile rehabilitation of the ED patients after radical prostatectomy. It seems proper to recommend daily use of a vacuum erection device plus oral PDE5I in the early postoperative period. For those who fail to respond to this therapy, intraurethral alprostadil, intracorporal injections, or a penile prosthesis could be considered.
Alprostadil ; administration & dosage ; Combined Modality Therapy ; Erectile Dysfunction ; etiology ; therapy ; Humans ; Male ; Penile Erection ; Penile Prosthesis ; Phosphodiesterase 5 Inhibitors ; administration & dosage ; Prostatectomy ; adverse effects ; Quality of Life ; Recovery of Function ; Vacuum

Radiation pneumonia is a part of radiation-induced lung injury, and its injury and repair is a complex pathophysiological process involving with the participation and interaction among numerous cells and cytokines. Early diagnosis and treatment of radiation pneumonia can alleviate lung injury and protect lung fuction. Compared with infectious pneumonia, there is no obvious difference in symptoms and physical signs. However, the symptoms are relatively mild, the total count of white blood cells is not significantly elevated or only the classification of neutrophils is relatively high. Hormone can stimulate the increase of white blood cells, which should be delivered prior to relevant examination. CT scan is a sensitive tool to make the diagnosis of radiation pneumonia, which can be utilized for staging, guiding treatment and prognosis evaluation. The lung injury changes of radiation pneumonia on CT scan can be observed 7-10 d later than relevant symptoms. Besides symptomatic treatment, such as cough relief and phlegm elimination, hormone is the key treatment of radiation pneumonia. It is recommended to deliver long-acting dexamethasone or prednisone with an initial small dose, adjusted to effective dose according to disease condition, maintained for 3-4 weeks, and gradually reduced to avoid the recurrence of radiation pneumonia. Pulse therapy for hormone is likely to lead to insufficient or excessive dose and affect the therapeutic effect. Insufficient dose can cause the occurrence of recurrent radiation pneumonia.

Objective:To determine if growth hormone (GH) and glutamine (Gln) reduce the time and dose of parenteral nutrition (PN) in patients with short bowel syndrome. Methods: Sixteen PN-dependent patients with short bowel syndrome were randomly assigned to Group A (control, oral Gln [0.6 g/kg/d] + GH placebo + diet, n= 5), B (Gln placebo + GH [8 IU/d] + diet, n= 5), and C (Gln + GH + diet, n= 6). PN volume and content were determined by standard criteria based on clinical measurements. After 4 weeks, GH and GH placebo were discontinued, but the diet with Gln or Gln placebo was continued for 12 weeks. Results: Group B showed greater reductions in PN volume, PN calorie and PN frequency than Group A (P

Objective To evaluate the interventional chemoembolization combined with proton radiotherapy in the treatment of hepatocellular carcinoma (HCC) accompanied with cancerous thrombus in the main portal vein. Methods Interventional chemoembolization combined with proton radiotherapy was performed in 46 patients of HCC accompanied with cancerous thrombus in the main portal vein. The proton radiotherapy was broke up into several fractions. The patients were treated with interventional chemoembolization and, alternatively, with proton radiotherapy. The short-term effectiveness and radiation reaction were evaluated. The survival rate was followed up. Results The effective rate was 91.3% . Disappearance of cancerous thrombus in the main portal vein was seen in 45.6% of patients. The liver functions were well restored, with a remarkable reduction in AFP. No acute or delayed radiation-induced hepatic damage or radiation hepatopathy occurred during the course of and after radiotherapy. The survival rate at 1, 6, 12 and 24 months was 100%, 89.1%, 52.2% and 21.4% respectively, with a median survival period of 17.6 months. Conclusion For the patients of HCC accompanied with cancerous thrombus in the main portal vein, interventional chemoembolization combined with proton radiotherapy is an effective, safe and newly-developed therapy.