2.Effect Comparative Analysis of Sodium Hyaluronate and Chitosan in the Prevention of Thyroid Postopera-tive Adhesion
Qiang SHEN ; Quan WANG ; Junjie YANG
China Pharmacist 2014;(2):266-268
Objective:To investigate and compare the effect of sodium hyaluronate and chitosan in the prevention of thyroid post-operative adhesion. Methods:Totally 84 patients with thyroid operation in our hospital from August 2012 to August 2013 were select-ed, and according to the admission time, the patients were respectively divided into group A and B with 42 cases each. In order to pre-vent postoperative adhesion, group A was treated with sodium hyaluronate, and group B was treated with chitosan. The clinical curative effect of the two groups was compared. Results: The adhesion rate in group A was 14. 3%(6/42), which was higher than that in group B (3/42 7. 1%), while the difference was not statistically significant (P>0. 05). All the patients showed no bleeding, aller-gies and other adverse reactions, only in group A, 2 mild infection (4. 8%) occurred. The adverse reactions in the two groups were without significant difference (P>0.05). Conclusion: Sodium hyaluronate and chitosan both have the preventive effect on thyroid postoperative adhesion with similar efficiency and adverse reactions.
3.Preparation and application of multicellular spheroid in cancer therapy
Qiang XU ; Quan LIAO ; Yupei ZHAO
Basic & Clinical Medicine 2010;30(3):320-324
Multicellular spheroid (MCS) can simulate many aspects of the in vivo physiological and pathological conditions in many aspects,better reflect the in-vivo behavior of cells in tumors.So it's increasingly accepted as a valuable tool for evaluating the efficacy of therapeutic intervention including chemotherapy,radiotherapy,immunotherapy and combined therapy.Various spheroid co-culture approaches have been presented to study heterologous cells interaction in solid tumors.The present review briefly introduces the methodology and applications of MCS with focus on the up-to-date information.
4.Comparison of effect of standard Gamma nail and proximal femoral nail anti-rotation for geriatric intertrochanteric fractures
Quan JI ; Qingyun XUE ; Qiang WANG
Orthopedic Journal of China 2006;0(10):-
[Objective]To investigate and compare the effects of standard gamma nail (SGN) and proximal femoral nail anti-rotation (PFNA) in the treatment of osteoporotic intertrochanteric fractures in the elderly.[Method]From May 2002 to September 2005,55 patients with intertrochanteric fractures were treated with SGN.Sixty-eight patients were treated with PFNA from November 2005 to June 2008.The effects of the two implants about perioperative complications,bone healing and the function of the operated hip joint were compared.[Result]No statistically significant difference was found between the two groups in blood loss,blood transfusion,infection,deep venous thrombosis and hospital stay.One patient developed femoral head avascular necrosis postoperatively in Gamma nail group.The incidence of postoperative hip pain in Gamma nail group was higher than that in the PFNA group,but there was no significant difference in the Harris score.[Conclusion]Gamma nail and PFNA nail are reliable methods to treat geriatric intertrochanteric fractures,with advantages of minimal iatrogenic injury,stable fixation and few complications.
5.Report of case with laryngeal nerve palsy and tracheal cartilage necrosis after thyroid microwave ablation.
Qing-quan ZHANG ; Shao-hong JIANG ; Qiang WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(9):773-774
Cartilage
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pathology
;
Catheter Ablation
;
adverse effects
;
methods
;
Female
;
Humans
;
Laryngeal Nerves
;
Microwaves
;
Middle Aged
;
Necrosis
;
Thyroid Gland
;
surgery
;
Trachea
;
pathology
;
Vocal Cord Paralysis
;
etiology
8.Minimally invasive plate osteosynthesis for treatment of proximal humeral fractures through anterolateral acromial approach
Quan ZHANG ; Ning SUN ; Qiang HUANG ; Shiwen ZHU
Journal of Peking University(Health Sciences) 2017;49(2):242-245
Objective:To investigate the feasibility,surgical technique and effect of osteosynthesis for proximal humerus fractures through the minimal incision anterolateral acromion.Methods: In this study,32 patients of proximal humeral fractures were selected and treated through the minimal incision antero-lateral acromion between January 2012 and October 2014.Of these patients,there were 19 males and 13 females,with mean age 46 years old (range: 22-78 years).The mechanism of injury was a trauma of simple fall for 21 patients and motor vehicle accident for 11 patients.According to Neer classification,18 cases had two-part fractures,12 had three-part fractures,and 2 had four-part fractures.All patients were sustained operation of open reduction and internal fixation.The average delay between trauma and surgery was 4 d (0.5-10.0 d).The operations were performed in invariable operating room with general anesthesia.The fractures were reduced and immobilized with anatomical locking plate through the minimal incision anterolateral acromion during operation.Patients were received passive motion after operation.Results: All the 32 cases were followed up ranging from 3 to 34 months with an average of 11 months.All the fractures were healed.There was neither failure of internal fixation nor incision infection case.The functional results of the shoulder,according to Constant-Murley score was on an average 86 (range: 69-100).Conclusion: The treatment for proximal humeral fractures through the minimal incision anterola-teral acromion approach is a feasible and effective method,which shows good results for treating proximal humerus fractures with correct indication.There are several advantages compared with conventional deltopectoral approach.They are minimal soft tissue disruption,minimal blood loss and easily to manipulate technique.But it required selection of indication strictly and surgeon's experience.
9.Type of adenoidal hypertrophy by nasal endoscopic and clinical significance.
Qing-quan ZHANG ; Qiang WANG ; Xiu-mei CHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(10):859-860
Adenoids
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diagnostic imaging
;
pathology
;
surgery
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Adolescent
;
Child
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Child, Preschool
;
Endoscopy
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Female
;
Humans
;
Hypertrophy
;
diagnostic imaging
;
pathology
;
surgery
;
Male
;
Nasopharyngeal Diseases
;
diagnostic imaging
;
pathology
;
surgery
;
Nose
;
surgery
;
Radiography
10.A case report of pterygopalatine fossa communication arachnoid cyst.
Qiang WANG ; Qing-quan ZHANG ; Shao-hong JIANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2013;48(3):250-251
Endoscopy
;
methods
;
Female
;
Humans
;
Meningocele
;
surgery
;
Middle Aged
;
Pterygopalatine Fossa
;
surgery