2.Effect Comparative Analysis of Sodium Hyaluronate and Chitosan in the Prevention of Thyroid Postopera-tive Adhesion
Qiang SHEN ; Quan WANG ; Junjie YANG
China Pharmacist 2014;(2):266-268
Objective:To investigate and compare the effect of sodium hyaluronate and chitosan in the prevention of thyroid post-operative adhesion. Methods:Totally 84 patients with thyroid operation in our hospital from August 2012 to August 2013 were select-ed, and according to the admission time, the patients were respectively divided into group A and B with 42 cases each. In order to pre-vent postoperative adhesion, group A was treated with sodium hyaluronate, and group B was treated with chitosan. The clinical curative effect of the two groups was compared. Results: The adhesion rate in group A was 14. 3%(6/42), which was higher than that in group B (3/42 7. 1%), while the difference was not statistically significant (P>0. 05). All the patients showed no bleeding, aller-gies and other adverse reactions, only in group A, 2 mild infection (4. 8%) occurred. The adverse reactions in the two groups were without significant difference (P>0.05). Conclusion: Sodium hyaluronate and chitosan both have the preventive effect on thyroid postoperative adhesion with similar efficiency and adverse reactions.
3.Preparation and application of multicellular spheroid in cancer therapy
Qiang XU ; Quan LIAO ; Yupei ZHAO
Basic & Clinical Medicine 2010;30(3):320-324
Multicellular spheroid (MCS) can simulate many aspects of the in vivo physiological and pathological conditions in many aspects,better reflect the in-vivo behavior of cells in tumors.So it's increasingly accepted as a valuable tool for evaluating the efficacy of therapeutic intervention including chemotherapy,radiotherapy,immunotherapy and combined therapy.Various spheroid co-culture approaches have been presented to study heterologous cells interaction in solid tumors.The present review briefly introduces the methodology and applications of MCS with focus on the up-to-date information.
4.Comparison of effect of standard Gamma nail and proximal femoral nail anti-rotation for geriatric intertrochanteric fractures
Quan JI ; Qingyun XUE ; Qiang WANG
Orthopedic Journal of China 2006;0(10):-
[Objective]To investigate and compare the effects of standard gamma nail (SGN) and proximal femoral nail anti-rotation (PFNA) in the treatment of osteoporotic intertrochanteric fractures in the elderly.[Method]From May 2002 to September 2005,55 patients with intertrochanteric fractures were treated with SGN.Sixty-eight patients were treated with PFNA from November 2005 to June 2008.The effects of the two implants about perioperative complications,bone healing and the function of the operated hip joint were compared.[Result]No statistically significant difference was found between the two groups in blood loss,blood transfusion,infection,deep venous thrombosis and hospital stay.One patient developed femoral head avascular necrosis postoperatively in Gamma nail group.The incidence of postoperative hip pain in Gamma nail group was higher than that in the PFNA group,but there was no significant difference in the Harris score.[Conclusion]Gamma nail and PFNA nail are reliable methods to treat geriatric intertrochanteric fractures,with advantages of minimal iatrogenic injury,stable fixation and few complications.
5.Report of case with laryngeal nerve palsy and tracheal cartilage necrosis after thyroid microwave ablation.
Qing-quan ZHANG ; Shao-hong JIANG ; Qiang WANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(9):773-774
Cartilage
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pathology
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Catheter Ablation
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adverse effects
;
methods
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Female
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Humans
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Laryngeal Nerves
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Microwaves
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Middle Aged
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Necrosis
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Thyroid Gland
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surgery
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Trachea
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pathology
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Vocal Cord Paralysis
;
etiology
7.A case report of pterygopalatine fossa communication arachnoid cyst.
Qiang WANG ; Qing-quan ZHANG ; Shao-hong JIANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2013;48(3):250-251
Endoscopy
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methods
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Female
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Humans
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Meningocele
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surgery
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Middle Aged
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Pterygopalatine Fossa
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surgery
8.Type of adenoidal hypertrophy by nasal endoscopic and clinical significance.
Qing-quan ZHANG ; Qiang WANG ; Xiu-mei CHEN
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(10):859-860
Adenoids
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diagnostic imaging
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pathology
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surgery
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Adolescent
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Child
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Child, Preschool
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Endoscopy
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Female
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Humans
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Hypertrophy
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diagnostic imaging
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pathology
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surgery
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Male
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Nasopharyngeal Diseases
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diagnostic imaging
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pathology
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surgery
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Nose
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surgery
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Radiography
10.Analysis of human papillomavirus 16 subtypes E2 gene and long control region sequence in Chengdu
Gangyi CHEN ; Xianping DING ; Lin CHEN ; Qiang QUAN ; Shuangshuang NIE
Chinese Journal of Infectious Diseases 2013;(5):290-294
Objective To explore the relevance between sequence variation of human papillomavirus (HPV)16 subtypes E2 gene or long control region (LCR) and cervical lesions.Methods Fifty specimens from HPV16 infected people in Chengdu were collected,including cervical exfoliated cells from 38 HPV carriers,papilloma tissues from 8 cases of genital warts,2 with cervical intraepithelial neoplasia (CIN) Ⅱ and 2 with CIN Ⅲ in this study.Polymerase chain reaction was used to amplify E2 gene and LCR,then an evolutionary tree was constructed.Results In all the 50 specimens,there were 12 mutation sites in E2 gene,among which,C→A existed in one specimen of genital warts,and ≥2 mutation sites existed in all the other 48 specimens.There were 28 mutation sites of LCR sequence of all the specimens.Ten specimens were chosen to construct evolutionary tree and were sequenced.The data showed that 8 specimens were Asian variants,E2 gene mutation existed in all the specimens while the LCR 7867 G→A only existed in the four CIN.Conclusion LCR 7867G→A is a correlative mutation site of cervical lesions in Chengdu.