Objective:To study the effects and mechanisms of Hongqi formular combined with exercise preconditioning against myocardial ischemic reperfusion injury in rats.Method:Fifty health male SD rats were randomly divided into sham,IR,EP,HP and EHP group.After establishing of EP animal model,the rats were ligated ramus descendens coronary artery to induce myocardial ischemic reperfusion model.The serum cardiac troponin Ⅰ (cTn Ⅰ),myocardium IL-6,TNF-α were detected by enzyme linked immunosorbent assay (ELISA).The myocardium MDA was detected by chemical colorimetry method.The myocardium SOD was detected by xanthine hydrocarbonylation.The serum ET,6-k-PGF1α,TXB2 density were detected by radioimmunoassay,and the myocardium Ca2+ density was detected by atom absorption spectrophotometry.Result:①As compared with the group IR,the serum cTn Ⅰ decreased significantly in groups EP,HP and EHP;As compared with the group EHP,the cTn Ⅰ level in serum was increased in groups EP and HP.②As compared with the group IR,the Ca2+ level in myocardial sarcoplasmic reticulum was decreased significantly in groups EP,HP and EHP;As compared with the group EHP,the Ca2+ level in myocardial sarcoplasmic reticulum was decreased significantly in group EP.③As compared with the group IR,the ET in serum were decreased significantly in groups EP,HP and EHP;As compared with the group EHP,the ET,TXB2 in serum were increased significantly in groups EP and the 6-k-PGF1αin serum were decreased significantly in groups EP.④As compared with the group IR,the IL-6 and TNF-α in cardiac muscle were decreased in groups EP,HP and EHP;As compared with the group EHP,the IL-6 and TNF-α in cardiac muscle were increased in groups EP and HP.⑤As compared with the group IR,the SOD in cardiac muscle was increased significantly in groups EP,HP and EHP and the MDA in cardiac muscle was decreased significantly in groups EP,HP and EHP;As compared with the group EHP,the SOD in cardiac muscle was decreased significantly in groups EP and the MDA in cardiac muscle was decreased significantly in group EP.Conclusion:Hongqi formular combined with exercise preconditioning produces cardio-protective effect during myocardial ischemic reperfusion,which may be related with the enhanced anti-oxidant ability,the decreased blood cell damage,the maintainace of vascular endothelium function,the improved microcirculation and the decreased calcium overloading.

Objective To analyze the relationship between alexithymia and patients' satisfaction under the condition of good quality in the esthetic characters. Methods 211 patients requiring single anterior tooth restoration were treated with all ceramic crowns which were assessed by the good and moderate degrees. Patients received 20-item Toronto Alexithymia Scale (TAS-20) and a visual analogue scale assessing patients' satisfaction (VAS). Chi-squared analysis, correlation analysis and the general linear modeling procedure were calculated for TAS total and factors scores according to age, gender and dichotomized satisfaction. Results 85. 3% patients belonged to the high satisfaction group(VAS scores 80 or higher) and 7.1% reported alexithymia ( total score 61 or higher). No difference across gender was observed in the prevalence of alexithymia and satisfaction. Age was correlated with the TAS scores ( r=0.629) and satisfaction scores ( r= -0.429). According to dichotomized satisfaction,TAS total and factor 1&2 scores were significantly different. When adjusting for the effect of age,the association was existed between TAS scores and san'sfaction( r= -0.68). Conclusion Alexithymia has effect on dental satisfaction.

Idiopathic scoliosis is a common disorder in spinal surgery, and operative intervention with three-dimensional interfixation is an effective treatment for it. Postoperative evaluation of spinal balance is an important index to evaluate the efficacy of the operative intervention. The radiologic parameters for evaluating postoperative spinal balance in coronal, sagittal and axial view were reviewed in this article.

Evolution, Molecular ; Humans ; Influenza A virus ; genetics ; Influenza, Human ; epidemiology

Cytomegalovirus(CMV) is an important pathogen of congenital and postnatal infections in children,which causes a series of acute and chronic infectious diseases and nervous system sequelaes.Early and accurate diagnosis of pediatric CMV infection is an effective way to improve health in children.This paper will introduce the types,laboratory techniques and diagnostic strategies of CMV infection based on the diagnostic standards at home and abroad,and also focus on current progress in diagnosis of pediatric CMV infection.

Humans ; Infant, Newborn ; Intermittent Positive-Pressure Ventilation

Objective To investigate the correlation between the unilateral middle cerebral artery (MCA)stenosis ratio and cerebrovascular reserve(CVR) using computed tomography perfusion (CTP) and CO2 inhalation test in patients with unilateral middle cerebral artery stenosis.Methods CTP were performed in 31 patients who were diagnosed as unilateral middle cerebral stenosis before and after CO2 inhalation.The basal ganglia and radial dimension were selected as interested regions (thickness 8 mm).The value of cerebral blood flow (CBF) was measured and the mean CBF values of all interested regions in each MCA territory were harvested separately.Then the CVR of each MCA territory was calculated according to the following formula:CVR =(CBF after CO2 inhalation test-CBF before CO2 inhalation test)/ CBF before CO2 inhalation test × 100％.Patients were divided into two groups:the severe stenosis group and the moderate stenosis group.The association between the MCA stenosis ratio and the CVR values was investigated.Results In 31 patients,different changes of CBF were found in affected MCA territory after CO2 inhalation.CBF increased in 17 cases,unchanged in 2 cases and decreased in 12 cases.A decreased CVR was detected in 51.6％ of the patients(16/31) and more likely found in the severe stenosis group (13/19) than that in the moderate stenosis group(3/12,P =0.029).The degree of stenosis in MCA was also significantly correlated with the changes of CVR(r =0.423,P =0.018).Conclusions CVR is decreased in some patients with unilateral MCA stenosis and significantly correlates with the severity of stenosis in MCA.

Child ; Humans ; Karyotyping ; Male ; Osteochondrodysplasias ; classification ; diagnosis ; genetics

Congresses as Topic ; Otolaryngology