1.Clinical Observation of Acupuncture plus Electromyographic Biofeedback Therapy for Cerebral Stroke Hemiplegia
Shanghai Journal of Acupuncture and Moxibustion 2016;35(10):1178-1180
Objective To observe the effect of acupuncture plus electromyographic biofeedback therapy (EMGBFT) on the nerve function, activities of daily life (ADL), biochemical indexes, and lower-limb function in cerebral stroke patients. Method Totally 102 cerebral stroke patients in recovery stage were recruited and allocated to an observation group and a control group by using the random number table, 51 cases in each group. The two groups were both given conventional treatment, based on which, the control group was given EMGBFT, while the observation group was given acupuncture plus EMGBFT. The treatment duration was 8 weeks in both groups. The changes of National Institute of Health Stroke Scale (NIHSS), ADL, endothelin 1 (ET-1), calcitonin gene-related peptide (CGRP), and Fugl-Meyer Assessment (FMA) of the lower-limb motor function were compared. Result The NIHSS scores dropped and ADL scores increased significantly in the two groups after the intervention (P<0.05);after the intervention, the NIHSS score of the observation group was lower than that of the control group and the ADL score was higher than that of the control group (P<0.05);in the observation group, the plasma ET-1 level decreased significantly and CGRP level increased significantly after the intervention (P<0.05);after the treatment, the plasma ET-1 level in the observation group was lower than that in the control group and the CGRP level was higher than that in the control group (P<0.05);the FMA scores increased markedly in both groups after the intervention (P<0.05);the FMA score of the observation group was higher than that of the control group after the treatment (P<0.05). Conclusion Acupuncture plus EMGBFT can significantly improve the nerve function and ADL, promote the recovery of lower-limb function, down-regulate the ET-1 level, and up-regulate the CGRP level in cerebral stroke patients.
2.The effects of resuscitation with limited fluid on rabbits with uncontrolled hemorrhagic shock
Zhenjie WANG ; Shiyou ZHENG ; Fei WANG ; Qianfen CHEN
Chinese Journal of Emergency Medicine 2009;18(2):154-157
Objective To investigate the effects of resuscitation with limited fluid on rabbits with uncon-trolled hemordaagic shock. Method Uncontrolled hemorrhagic shock was produced in 40 rabbits. When the mean arterial pressure dropped to 40 manI-Ig and maintained for 30 minutes, resuscitation was initiated with Ringer solu-tion infusion into rabbits in large volume for group N3 (125 mL/kg) ,moderate volume for group N2 (92 mL/kg) and small amount for group N1 (57 mL/kg), and a drop of fluid was not given to rabbits of group N4. Besides, rob-bits of group N5 were controls without shock. MAP, fatality, volume of blood loss, SOD and Her were observed for 120 minutes or until death. Data were analyzed using SNK-q test and rank test. Results MAP, SOD and Het were higher, and fatality and blood loss were lower in group N5 than those in groups N1, N2,and N3 (P<0.01 ). MAP,fatality,blood loss and Het of group N4 were worse than those of groups N1,N2 and N3 (P<0.01). The blood loss and fatality in group N3 were significantly higher than those in groups N1 and N2 (P<0.01 ). SOD of kidney in group N3 was significantly lower than that in group N1 and N2(P<0.01). As the volume of fluid in-creased during resuscitation, Het of all animals was gradually becoming lower. As MAPS in groups N2, N3 and N4 were gradually becoming lower and lower, death increased. Conclusions Limited fluid resuscitation (57~92mL/kg) should be recommended to the therapeutic strategy for uncontrolled hemorrhagic shock.