Objective: To establish a method of HPLC for determination of chlorogenic acid and baicalin in Yinhuang Oral Liquid (Flos lonicerae, Radix Scutellariae). Methods: LUNA C18(2) column was used. The acetonitrile 0.1% phosphoric acid solution was used as the mobile phase. The flow rate was 1.0mL?min -1 . The detection wavelength was set as 318nm. Results: For chlorogenic acid, the linear range was 0.2568 ～ 2.0544 ?g, and the average recovery rate was 97.7% with RSD =0.8%. For baicalin, the linear range was 0.9896 ～7.9168?g, and the average recovery rate was 98.0% with RSD =0.9%. Conclusion: The method is simple, reliable, accurate and can be applied to the quality control of the preparation.

Customized management based on chemotherapy initiated a new era in the treatment of retinoblastoma(RB).Many domestic ophthalmic centers are making beneficial attempts in this domain.However,the understanding of the trend needs to be improved throughout the country.In this article,a brief comment in five aspects is done in order to break the obsolete opinion and generalize the international classification of RB;correct some misunderstandings;promote an awareness campaign for early diagnosis;enhance the multi-center cooperation to improve the quality of clinical studies and start clinical and experimental research on RB.

Female ; Fertility ; drug effects ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive ; drug therapy ; physiopathology ; Pregnancy ; Protein Kinase Inhibitors ; pharmacology ; therapeutic use

Objective To investigate the changes of brain angiography in patients with virus encephalitis.Methods Examining 5 patients with herpes simplex virus encephalitis and 2 patients with Epstein-Barr(EB)virus encephalitis by digital subtractiona angiography(DSA)system and compares the results with control group(including 10 headache patients).Results The results of DSA of virus encephalitis patients were all abnormal,the outcome was accelerating blood circle like irritation.The average of the whole time of brain artery and vein circle was 6.71 seconds,while the results of DSA examination of the control group were all normal,the whole time of brain circle was 10.25 seconds.There was significant difference between the two groups(P

Retinoblastoma is the most common intraoeular malignant tumor in children.In its treatment,drug therapy is one of the most effective and irreplaceable methods.To reduce the toxicity of drugs,enhance the therapeutic effect and lessen drug resistance, some new drug deliver systems and new medicines for retinoblastoma are coming into being.Ophthalmic arterial infusion,fibrin sealant and iontophoresis are newly-found drug deliver systems.And the latest drugs under research include nutlins,phenoxazine derivative Phx-1,combretastatin A4 phosphate,2-deoxy-d-glucose and histone deacetylase inhibitors,etc.The following text is focused on the two aspects of the drug therapy for retinoblastoma.

OBJECTIVE To evaluate the present condition of bacteriological infection caused by drainage tube after modified radical mastectomy(MRM) and the prevention measure.METHODS Atotal of152 patients with drainage tube after MRM during 2005-2007 were analyzed,bacteria culture of drainage fluid from breast wound or axillary wound were taken in 24 hours after operation.The bacteria or fungi were identified with ATB bacterial analysis apparatus.RESULTS Seventy specimens from 52 patients were positive(positive rate 34.2%).Of 70 strains,40 were Gram-positive cocci,24 were Gram-negative bacilli and the other 6 were fungi.The reasons of infection included subsided immunity defense system,drainage tube application,incorrect aseptic processing or disinfection procedure,and obstruction of drainage tube.CONCLUSIONS The important prevention measures of bacteria infection through drainage tube after MRM include maintenance of aseptic environment in operating room,strict aseptic processing,fluent drainage,and proper indwelling time of drainage tube.

Combined with the routine work of preventing and treating diseases, the construction of a clean and honest administration in stomatological hospital would be beneficial to raise the administrative staff's awareness of the constructive characteristics of a clean and honest administration in their work belief and methods to enhance the work initiative and effectiveness.

Being one of the most important complications and also one of the leading cavses of death, venous thromboembolism ( VTE) could significantly increase the morbidity and mortality of patients with tumor.Therefore, accurate assessment of VTE risk and early prophylaxis according to the risk level are important to reduce the incidence of VTE, as well as to improve the quality of life and disease prognosisin patients with cancer.In this paper, we introduced the laboratory indicators that could be used for risk assessment of tumor-associated VTE and monitoring of prophylaxis and treatment in tumor patients with VTE.We aimed to strengthen the awareness of tumor-associated VTE and expected to provide help for clinical practice.

Acute poisoning occurs in age of children and threatens children's life.In developed country,monitoring network about children's poisoning showed related risk factors,which helped preventing and managing poisoning quickly.The fatality rate of children's poisoning is high in China.There is no monitoring network in our country.We summarized the influencing factors and treatment of acute poisoning in children.

BACKGROUND:Soft tissue releasing is a major means of correcting knee flexion contracture, and the soft tissue releasing methods are different for different knee joint diseases and degrees of deformity. Ideal soft tissue balance can gain a clear functional recovery and deformity correction from severe knee flexion contracture after total knee arthroplasty.
OBJECTIVE:To study the proper handling of knee flexion contracture and soft tissue releasing in total knee arthroplasty.
METHODS:Twenty-six cases of knee deformity in 20 ° to 60 ° receiving primary total knee arthroplasty were retrospectively studies. Steps of soft tissue releasing and residue deformity after each step were recorded. Postoperative fol ow-up was 12 months on average.
RESULTS AND CONCLUSION:The 26 cases were recovered from knee flexion deformity after soft tissue release. Posterior capsular release was carried out in al cases to different extents, and the flexion deformity and postoperative range were corrected and greatly improved, respectively. These indicate that the posterior capsular release and lateral col ateral ligament release can correct most of the flexion deformity, but increasing the distal femoral osteotomy is not necessary.