Objective To study effects of hydrated rate on compressed deformation properties of natural articular cartilage.Methods The mass losses of pure cartilage,subchondral bone and cartilage sample were measured under different volatilization time with constant vacuum temperature container of 40 ℃,and confined compressed deformation of different hydrated rates was measured using UMT-2 multi-specimen test system.Combined with cartilage structural equation originated by Mow,the aggregated modulus and permeability of cartilage tissue were obtained.Results The mass losses of pure cartilage,subchondral bone and cartilage sample functioned with a non-linear ascending relation with volatilization time in the environmental temperature of 40 ℃.The volatilization time for different hydrated rates of 75%,50%,25%and 0% was 17 min,35 min,54 min and 100 min,respectively.Higher hydrated rate produced more compressed deformation,lower aggregated modulus and higher permeability.Conclusion The viscoelastic mechanisms of flow-dependence and flow-independence are manifested by compressed deformations while the aggregated modulus and permeability could quantitatively depict the mutual relation between hydrated rate and compressed deformation.

Benzene ; Benzene Derivatives ; Bile ; Chromatography, Gas ; Gallbladder ; Gas Chromatography-Mass Spectrometry ; Humans ; Toluene

Objective To develop a system achieving automated real-time tracking and localizing of tumor center in radiotherapy. Methods High-accuracy infrared tracking cameras' coordinate system was calibrated with the treatment machine. A kind of passive marker was introduced, which can be imaged by computed tomography and can be localized by the infrared cameras during radiotherapy. Several markers on the surface of the thermal-shaped film were fixed, and then the real-time co-ordinates of the markers was compared with those obtained from the computed tomography. With subsequent space registration, the position biases could be shown finally, which could help achieving the real-time tracking and localizing of the tumor center. Results With infrared tracking cameras and appropriate software, the system can achieve automated and real-time localization in radiotherapy. Conclusion The system is more automated, accurate and speedy than the traditional localization method.

Background Hypertension and dyslipidemia are the 2 important risk factors of cardiovascular affecting the prognosis of cardiovascular disease. However paucity data of characteristics of lipid metabolism and prognosis of cardiovascular diseases in high-risk groups with hypertension are available. Objective To analyze the lipid metabolism level and the relevant risk factors of inpatients with essential hypertension (EH) from 2000 to 2007. Methods Retrospective study was performed based on the clinical characteristic and the relationship between different kinds of hyperlipidemia and target organ damages in inpatient with EH. Results For the level of triglyceride (TG) and the prevalence of hypertriglyceridemia,males(n=3056) were significantly higher than females(n=1932)(P

Objective To evaluate the incidence of contrast-induced nephropathy(CIN)in non-selected patients undergoing coronary angiography and intervention,and to investigate,the clinic risk factors of CIN as well as the renal safety of isosmolar iodixanol.Methods A total of 532 patients undergoing diagnostic coronary angiography or percutaneous coronary intervention were enrolled.Serum creatinine(SCr)was measured at any time within a week before the procedure and 2 days(48 hours)post procedure.The definition of CIN is the increase of serum creatinine of 44.2 ?mol/L(0.5 mg/dL)or 25% of the baseline at 48 hours after the use of contrast media.The effects of contrast media on renal function in patients undergoing coronary intervention were investigated and predictors of CIN were determined using logistic regression test.Results(1)Among the 532 patients,CIN occurred in 29 patients and the incidence of CIN in non-selected patients was 5.5%.(2)The incidence of CIN was significantly higher in patients with baseline eGFR

Objective To establish an influencing factors system for the implementation effect of the vertical integration of services between the hospitals and community health service institutions.Methods Primary data related to influencing indicators were collected by literature review,questionnaire method and in-depth interview,and then the analytic hierarchy process (AHP) and Delphi method were used for the construction of final influencing factors indicator system.Results An influencing factors indicator system which coincides with the status of the vertical integration between hospitals and community health service institutions in Nanjing,Wuhan and Zhenjiang was established,including 4 firstlevel indicators,10 second-level indicators and 36 third-level indicators.Conclusion This study can provide a basis for hospitals and community health centers to improve the integration service system,and fill the gap of research on the influencing factors of the vertical integration of the domestic health care system,which are meaningful for the vertical integration of health care system in other districts and patterns.

Objective To investigate the clinical significance of intra-abdominal pressure measure in patients with liver transplantation by summarizing the data of 143 cases.Methods Intra-abdominal pressure was indirectly measured by urinary bladder pressure.Intra-abdominal pressure over 10 cm H2O (1 cm H2O=0.098 kPa) was regarded as intra-abdominal hypertension (IAH),and 10

Objective Through preliminary clinical use of stereotactically guided wire localization biopsy for nonpalpable breast lesions, we discussed the diagnostic accuracy of the technique and its value in early detection of breast carcinomas. Methods Stereotactically guided wire localization biopsy was performed on 26 lesions. The distance between the needle tip and disease center (D) was calculated and compared to that directly obtained from measurement of the localization between wire tip and center of the lesion. Localization was rated as excellent, good, and bad when D values were ≤2.5 mm, =2.6-4.9 mm, and ≥5.0 mm, respectively. Results Excellent, good, and bad localization results were achieved in 20, 5, and 1 procedures, respectively. These data correlated well with the direct measurements of the localization between wire tip and center of the lesion. Resection of 26 lesions on single operation was achieved and the median volume of the resected specimens was 10 5 cm 3. The breast carcinoma detection rate of 6/26 was achieved. Conclusion Our initial application of the technique showed that stereotactically guided wire localization biopsy for nonpalpable breast lesions was an effective tool for the localization and specification of breast lesions. It could avoid false negativity and help excise the entire lesion without excessive excision of the surrounding normal tissues. The technique was one of those that was worthy of more widely application for the preoperative diagnosis of nonpalpable breast lesions.

10 mm) treated by CBA or BA were retrospectively analyzed. CBA was used in 74 patients and BA in 43 patients. Results Initial success (residual restenosis ≤30% with no major complications) was achieved in 99% of cases in CBA group and 100% in cases of BA group. Follow-up angiography was performed in all patients at (5.8?1.6) months. The diameter stenosis percent after CBA was lower and the instant gain after CBA was larger than that after BA (11.81%?9.17% versus 26.33%?10.04% and 1.96?0.51 mm versus 1.51? 0.54 mm, respectively; P

0.05), but did inhibit activity of iNOS (P