Alzheimer Disease ; pathology ; Drugs, Chinese Herbal ; pharmacology ; Humans ; Rhodiola

This article reviewed the diagnosis and treatment of the main vascular diseases with surgical approach, especially the advance and challenge of endovascular therapy. Highlight of the basic studies on vascular surgery was briefly introduced. Also, the author proposes his recommendation on vascular surgeons training as well as the design and performance of multi-center prospective studies.
China ; Humans ; Vascular Surgical Procedures ; trends

Acupuncture Therapy ; Aged ; Female ; Hiccup ; etiology ; physiopathology ; therapy ; Humans ; Liver ; physiopathology ; Male ; Middle Aged ; Spleen ; physiopathology ; Stroke ; complications

Objective To explore effect of clinical pathway in turnout gene therapy's health education,to promote turnout sufferer's acknowledge of gene therapy,thus to better cooperate the treatment.Methods To apply the clinical pathway to the in-patient health education,to explain and evaluate to the turnout gene therapy's sufferer.Resuits The sufferers'acknowledge of tumour gene therapy promoted and their cognition of the therapy's side effect promoted,so they can better regard gene therapy.Simultaneously the relationship of nurse-sufferer improve and the nurse's ability of health education improved.Conclusion Clinical pathway has good using value in the health educadon of promoting turnout gene therapy's sufferer's acknowledge.

The rate of bone turnover in postmenopausal women accelerates and the newly formed osteoid is poorly mineralized, resulting in the loss of bone mineral content. Meanwhile, the requirement for calcium increases as more bone matrix needs to be mineralized. On the other hand, the reduction of serum estrogen level impairs the absorption of calcium in intestinal tract and the reabsorption in kidney, resulting in the decreased absorption and increased excretion of calcium. Therefore, sufficient calcium intake is critical for maintaining the bone structure in postmenopausal women. The reference intake of calcium differs greatly among different countries. In 2000, China established the adequate intake of calcium for Chinese women aged 50 years and older as 1000 mg/d. Diets provide the optimal source of calcium to prevent osteoporosis. Although calcium supplements have been demonstrated to be beneficial for the bone mineral density in postmenopausal women, its impact on fracture risk and cardiovascular diseases remains controversial. Available evidences suggest that calcium supplements combined with vitamin D are unlikely to increase the risk of cardiovascular diseases.

Objective To investigate the effects of noisy pressure support ventilation (Noisy PSV) in patients of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with respiratory failure, and to provide basic support for the new weaning mode for AECOPD. Methods A single-center, prospective, randomized, crossover clinical research was conducted. A total of forty-six AECOPD combined with respiratory failure patients who mechanically ventilated more than 24 hours in intensive care unit (ICU) of Tianjin Haihe Hospital from November 2014 to October 2015 were enrolled in this study. When the respiratory failure improved through conventional treatment, patients were mechanically ventilated with conventional PSV and Noisy PSV for two hours respectively in random sequence during spontaneous breathing recovery phase. The pressure support (PS) level was titrated to reach tidal volumes (Vt) about 8 mL/kg in both modes. The level of positive end-expiratory pressure (PEEP) and fraction of inspired oxygen were kept unchanged in both modes. The coefficient of variation of PS during Noisy PSV was set at 30%. Data of gas exchange, hemodynamics, lung functional parameters, breathing patterns and patient-ventilator synchrony were analyzed. Results All of the patients were well tolerated with the two modes, and no adverse reactions were found. The changes of gas exchange, hemodynamics, respiratory mechanics in PSV and Noisy PSV showed a clinical acceptable range. The variability of Vt was significantly increased in Noisy PSV mode than that in conventional PSV mode. While the number of asynchrony events was decreased in Noisy PSV mode than that in conventional PSV mode. Conclusion The Noisy PSV is safe and feasible for patients of AECOPD with respiratory failure, which may be a new weaning mode for AECOPD.

Digital construction and network service are the inevitable trend of the development of TCM literature modernization, and the model based on App Store has become the trend of electronic publications. This article analyzed the current status and existing main problems of the platform of TCM literature electronic publication. In view of the above problems, combined with the development of TCM literature electronic publication, this article proposed a transformation platform based on App Store, and further elaborated the function, design and technology of the platform.

Objective To investigate the potential mechanism of POD in the elder rat model in different depths of anesthesia. Method 120 elderly rats were randomly divided into the A1,A2,A3,B1,B2 and B3 groups. The incidence of POD in the elderly rats was assessed in different depths of anesthesia ,and then the death of neurons,and the expressions of Bid,Bim,Puma and Caspase?3 were detected by Annexin/PI ,real?time PCR and Western blot assay ,respectively. Results Compared with the A1 and A3 group ,the incidence of POD in the elderly rats was decreased and the death of neurons ,and the expressions of Bid ,Bim ,Puma and Caspase?3 were decreased in Group A2(P<0.05). Compared with the preoperative condition,the incidence of POD in the elder?ly rats was increased and the death of neurons,and the expressions of Bid,Bim,Puma and Caspase?3 were in?creased in all groups (P < 0.05). Additionally,similar results were found in the group of inhalational anesthesia. Conclusion The depth of BIS 60 ~ 75/BIS 30 ~ 45 in the elderly rats lead to the increase in the incidence of POD,and that might result from the apoptosis of neurons and the increases of Bid,Bim,Puma and Caspase?3.

Objective To study the effect of milrinone(Mil) and prostaglandin E1(PGE1) on postoperative right ventricular failure(RVF). Methods 28 patients with congenital heart diseases and pulmonary hypertension undergoing cardiopulmonary bypass (CPB) were randomly divided into four groups: control group (group I), receiving Mil (Group II), receiving PGE1 (Group III), and receiving both Mil and PGE1(group IV). The hemodynamic indexes of all the patients, including mean pulmonary artery pressure (PAP), mean arterial blood pressure (MAP), cardiac index(CI), systemic vascular resistance (SVR) and pulmonary vascular resistance(PVR), were measured and compared. Intubation time and side effects were observed. Results Compared with the other three groups, postoperative PAP、PVR and SVR in group IV deceased and CI increased significantly. The intubation time was also shorter in group IV. Conclusion Postoperative RVF can be treated efficiently by using Mil and PGE1.

0.05).Conclusion The rat model of liver-Qi stagnation can be induced by chronic stress,which is different from the syndromes of deficiency of both heart and spleen and the interior disturbance of phlegm-heat.