1.The application of CT cerebral perfusion imaging in patients with hyperacute stroke
Chinese Journal of Primary Medicine and Pharmacy 2011;18(6):745-746
Objective To explore the application of multislice computed tomographyic ( MSCT) perfusion imaging in the assessment of acute cerebral infarction. Methods 50 patients who initially diagnosed as acute cerebral infarction in 6 hours after their outbreak of infarction were selected. The Siemens semsation 4 MSCT was used to scan the patients and form time versus concentration curve analysis, including the comparision of region cerebral blood flow (CBF) between the necrosis region and the normal region, region cerebral blood volume (CBV), mean transit time ( MTT). Each case had to be examined by computed tomography at least once a week after infarction. Results 50 patients were found having a lower CBF and CBV in their necrosis region compared with the other side(P<0.05) ,and had a longer MTT in their necrosis region compared with the other side( P <0.05) ,45 patients were observed a shrink of the size of the infarction region compared with the perfusion image in first 6 hours when they were reexamined by CT a week later(P <0.05) ,which proved the exist of ischemic penumbra area around the infarction center. Conclusion The multislice computed tomographyic perfusion imaging technology could define the infarction region and size at the early stage of acute cerebral infarction. It also provided clues to indicate the exist of a vascular area around the necrosis centre. It could diagnose acute cerebral infarction at hyperacute period and provide image proof for the thrombolysis in early period and treatment in individual manner.
2.Practice and exploration on bilingual teaching for ophthalmology
Chinese Journal of Medical Education Research 2012;11(7):712-714
Bilingual teaching is a hot issue in the current medical education reform.This paper discussed the practice of bilingual teaching in ophthalmology education and explored the improvement of teaching materials,enhancement of teaching staff training and promotion of multimedia-based,web-based and PBL-based bilingual teaching in order to provide references for improving the quality of ophthalmology teaching.
3.Advances of Tei index in accessment of children's right ventricular in congenital heart disease
International Journal of Pediatrics 2013;(1):74-76
The value and detection of right ventricular in circulation have been paid more attention,.Because of the defects in traditional method,Tei index is the method in right ventricular measurement.The Tei index is sensitive in assessing RV function of patients with congenital heart disease.It is not affected by valve regurgitation and RV geometry.The Tei index is accurate and simple in estimating right ventricular function in congenital heart disease and is valuable and invasive index in estimating right ventricular functions.
4.The application of evidence-based nursing in standardized nursing of elderly hypertensive intracerebral hemorrhage patients with minimally invasive treatment
Chinese Journal of Practical Nursing 2014;30(18):35-37
Objective To investigate the effect of applying the evidence-based nursing in elderly hypertensive cerebral hemorrhage patients with minimally invasive therapy.Methods 78 cases of hypertensive cerebral hemorrhage patients with minimally invasive treatment were recruited from May 2010 to May 2011.According to the conventional method of random numbers,they were divided into the evidencebased group and the conventional group with 39 cases in each group.The evidence-based group received evidence-based nursing,while the conventional group received conventional clinical nursing.The nursing effect of the two groups was observed.Results The satisfaction degree of the evidence-based group and conventional nursing group was respectively 94.9% and 79.5 %.There was statistically significant differences.The score of SDS,SAS and BI before treatment between two groups showed no significant difference,while it showed statistically significant differences after treatment between two groups.The complication rate of the evidence-based group and the conventional nursing group was respectively 10.2% and 35.9%.There was statistically significant differences.Conclusions It is feasible to implement evidence-based nursing in the elderly hypertensive cerebral hemorrhage patients with minimally invasive therapy.It can effectively improve the patients' negative emotions,enhance daily living and quality of life.It is simple and can effectively reduce the incidence of complications.Thus,it is worthy of clinical application.
5.The expression and significance of ERα,ERβ,PR,and Bcl-2 of endometrial polyps
Chinese Journal of Primary Medicine and Pharmacy 2014;21(18):2781-2782
Objective To investigate the expression and significance of ERα (estrogen receptorα),ERβ(estrogen receptorβ),PR,and Bcl-2 of endometrial polyps.Methods 50 cases of endometrial polyp patients were studied.And 45 cases of endometrial normal subjects were selected as the control group.The enzyme-linked immunosorbent assay was used to detected the FSH,LH,E2,P,T and PRL six levels of the two groups.And endometrial ERα two groups of patients,ERβ,PR and Bcl-2 expression was studied.Results The FSH,LH,E2,P,T and PRL six levels of the two groups were no significant difference(P >0.05).Polyps in patients with proliferative phase of ERα,ERβ expression levels of the normal group had no significant difference (P > 0.05),the expression level of PR(0.47 ± 0.02) point was significantly lower than that of the normal group(0.53 ± 0.02) point (t =10.383,P =0.000),Bcl-2 expression levels(0.53 ± 0.04) point was significantly higher than that of the normal group (0.49 ± 0.02) point (t =4.322,P =0.000).Polyps in patients with secretory phase of ERα,Bcl-2 expression levels (0.46 ± 0.07;0.43 ±0.04)point were significantly higher than that of the normal group (0.37 ± 0.05 ;0.39 ± 0.03) point (t =5.007,P =0.000; t =3.834,P =0.000),the expression level of PR (0.42 ± 0.02) point was significantly lower than that of the normal group (0.46 ± 0.01)point(t =8.486,P =0.000),there was no significant difference in expression levels between the two groups ERβ(P >0.05).Between the two groups displayed,ERα,PR proliferative phase of the normal group and the polyp group,the expression levels of Bcl-2 were significantly higher than that of the secretory phase (P < 0.05).Conclusion The increase of the ERα,Bcl-2 expression levels,and the reduction of the level of PR expression in patients with endometrial polyps are closely related.
6.The value of procalcitonin in diagnosis of neonatal infection
International Journal of Pediatrics 2012;39(1):34-36
Neonatal infection is one of the important reasons for newborns mortality.The current diagnosis indicators of neonatal infection have differences in the sensitivity and specificity,respectively.In recent years,procalcitonin (PCT) is widely used in the diagnosis of various infectious diseases.Studies showed that the PCT had higher sensitivity and specificity in the early diagnosis of neonatal infection.Serum PCT level is associated with the severity of neonatal infection,the development and the prognosis of the disease.It can be used to evaluate the effect of treatment and the prognosis.During the period of neonatal,the serum PCT is not affected by the level of maternal and the acute inflammatory response which caused by injuries and asphyxia,and it is associated with the severity of newborn bacterial infection.PCT has special significance to the diagnosis of neonatal infection.
7.Study on intervention of impaired glucose tolerance patients in community with Chinese medicine
International Journal of Traditional Chinese Medicine 2012;34(10):879-881
ObjectiveTo observe the turnover of impaired glucose tolerance(IGT)patients intervened with different measures.MethodsIGT 158 patients found by physical examination in the community residents were randomly divided into health education group,Chinese medicine group,and western medicine group,and treated with health education,traditional Chinese medicine and western medicine respectively.The fasting blood glucose,oral glucose after 2hour blood glucose (2hPG),serum lipid,glycosylated hemoglobin index were observed.ResultsThe efficiency of patients with IGT was 48.0%,70.3% and 75.0% in health education group,Chinese medicine and western medicine respectively.There was significant difference of therapeutic effect between the western medicine group and health education group (x2=7.96,P<0.05),and between the traditional Chinese medicine group and health education group (x2=5.46,P<0.05),while there was no significant difference between the traditional Chinese medicine group and Western medicine group (x2 =2.31,P>0.05).ConclusionTraditional Chinese medicine and Western Medicine both have good effects on patients with IGT.But due to its good tolerability and few side effect,TCM may be more easily accepted by patients.
8.Effects of high dosage of atorvastatin in acute coronary syndrome patients on hsCRP and carotid atherosclerosis
Chinese Journal of Primary Medicine and Pharmacy 2012;19(5):703-705
Objective To study effects of high dosage of atorvastatin in acute coronary syndrome(ACS)patients on high sensitive creactive protein(hsCRP)and atherosclerosis.Methods 126 cases with ACS were divided into A,B and C group.30 patients in A group were given atorvastatin 20mg per night,41 cases in B group were given atorvastatin 40mg per night,while the other 55 patients in C group were taken atorvastatin 40mg per night and tirofiban in the first 24 to 48 hours.The patients were followed 6 months by evaluating serum hsCRP concentration,measuring the intimal thickness in the carotid artery with color Doppler.Results After treatment for 6 months,the patients in the three groups showed significant decrease in hsCRP,however,the therapeutic group showed significant difference amony the three groups.Additionally,the B and C groups further showed significant decrease in intimal thickness.Conclusion Using high-dose atorvastatin and tirofiban not only lowers hsCRP significantly,but also benefit stability of atherosclerotic plaque in carotid artery,and to reduce cardiovascular events.
9.Appilication of the CR low dose radiography in diagnosis for chronic obstructive pulmonary disease
Chinese Journal of Primary Medicine and Pharmacy 2013;20(6):806-807
Objective To investigate the CR low dose radiography to COPD in patients with pseudo normal phenomenon.Methods 160 cases of COPD diagnosed,stratified random dividing method according to the pulmonary function test values were divided into A,B,C and D group.Each group had 32 cases,at the same time,the increase in lung function in patients with mild to moderate pulmonary emphysema in 32 cases was E group,wich was treated with normal dose as a control group,in the normal dose and low dose CR photography failed to clear the diagnosis of emphysema,causing false normalization,statistical the case number,and verify the pulmonary function classification criteria,identify false normalization of lesions in such a case,the general rule to judge the feasibility analysis and prevention.Results There was no significant chifference among 5 groups of pseudo normal comparison (x2 =4.56,P >0.05).Conclusion Chronic obstructive pulmonary disease with low dose CR photography on severe and extremely severe patients is deteded by emphysema detection with rate high.Moderate,mild COPD detection rate is extremely low.
10.Analysis of a new model in nursing care ward round in the hand surgery department
Chinese Journal of Practical Nursing 2013;(15):53-55
Objective To analyze the effect of a new model in the nursing care ward round in the hand surgery department.Methods The implementation of nursing care ward round in the hand surgery department was retrospectively analyzed.Results The comprehensive quality of nurses were increased obviously when the new model ward round was implemented.Patients were more satisfied with the work of nursing care.The evaluation of new model ward round by nurses was higher than before.Conclusions The new model of nursing ward round showed a great help for increasing the comprehensive quality of nurses,the responsibility awareness of nurses and the nursing quality.It presented an significant application value by developing new nursing care technique and helping establish harmonious relationship between the nursing staff and patients.