Objective To explore the difference between the results of the cross-disciplinary joint teaching method and the traditional teaching method in medical humanity courses.Method 128 students in one military medical university were selected to be randomly assigned to the study group and the control group,using the cross-disciplinary joint teaching mode (study group,n=64) and traditional teaching mode (control group,n=64) in medical humanity courses.For the joint teaching mode,we compiled the teaching materials of medical humanities,formed the teaching team and organized the academic communication after class by social media.After all courses were finished,the subject cognition and approval of whole students were evaluated by the unified arranged examination and questionnaire.Then the data was processed by SPSS 18.0.Results On the aspect of subject cognition,the total scores of the study group were higher than control group in health law [(76.2 ± 3.34) vs.(72.5 ± 4.76);t=3.32,P=0.000] and medical ethics [(75.3 ±2.93) vs.(68.3 ± 3.10);t=4.01,P=0.000].On the aspect of subject approval,the recognition of the students of the study group in these three subjects were more than those of the control group except the selfevaluation of medical psychology (P=0.000).Conclusion The application of cross-disciplinary joint teaching method on medical humanity courses contributes evidently to the promotion of the medical humanity quality of clinical medical students.To implement this model,however,multi-sided resources are needed for colleges to coor-dinate,for perfect results require more practical exploration.

Objective To study the effects of ceftriaxone sodium(Cef) on the seizures and the expression of glutamate transporter (GLT-1) in kainic acid (KA) epilepsy model.Methods Firstly, a chronic spontaneous seizure mouse model was established by unilateral hippocampal injection of KA and monitored by vEEG technique to record seizures.The experimental group received intraperitoneal injection of Cef 200 mg/(kg·d) and the control group received normal saline.Seizure frequency, interictal spike waves and histological phenotypes were recorded to evaluate the function of Cef.Then we use the Western blot to detect the effect of expression for GLT-1.Results Unilateral hippocampal injection of KA 200 ng successfully established the mesial temporal lobe epilepsy model.Cef can reduce the seizures from 2.145 times/day to 1.597 times/day, decreased by 31.2% with a statistical significance(P<0.05).Cef treatment did not significantly enhance the expression of GLT-1.Conclusions Intraperitoneal injection of Cef partially inhibites the seizures of KA model, but the expression of GLT-1 in hippocampus is not enhanced.It is suggested that ceftriaxone may inhibit seizures through other mechanisms.

The procedure of occlusal treatment involves improving the morphology and the stomatognathic function.Several practical methods and morphological endpoints have been described in occlusal rehabilitation.We made a selection of these (mandibular position,oc-clusal plane,occlusal guidance,occlusal contact,face-bow transfer,use of an adjustable articulator and occlusal support)and performed a literature review to verify the existence of compelling scientific evidence for each of these.A literature search was conducted using Medline /PubMed in March 2011.Over 400 abstracts were reviewed,and more than 50 manuscripts selected.An additional hand search was also con-ducted.Of the many studies investigating stomatognathic function in relation to specific occlusal schemes,most studies were poorly designed and of low quality,thus yielding ambiguous results.Overall,there is no scientific evidence that supports any specific occlusal scheme being superior to others in terms of improving stomatognathic function,nor that sophisticated methods are superior to simpler ones in terms of clini-cal outcomes.However,it is obvious that the art of occlusal rehabilitation requires accurate,reproducible,easy and quick procedures to re-duce unnecessary technical failures and /or the requirement for compensatory adjustments.Therefore,despite the lack of scientific evidence for specific treatments,the acquisition of these general skills by dentists and attaining profound knowledge and skills in postgraduate training will be necessary for specialists in charge of complicated cases.

Objective To observe the influence of cervical traction and manipulation on hemorheology of cervical vertigo patients.Methods 59 patients in outpatients of our hospital from January 2012 to August 2013 were recruited and divided into a control group(29 patients)and a treatment group(30 patients)randomly. The control group was treated with flunarizine, and the treatment group was additionally treated with cervical traction and manipulation on the basis of the control group. After 4 therapeutic causes, evaluation of cervical vertigo symptoms and functions(ESOV)were performed and hemorheological changes were observed in both groups.Results① ESOV comparison: ESOV sores in both groupswere obviously improved after the treatment than the same group before the treatment(t=11.028, 5.825,all P<0.01)the treatment group were significantly lower than that in the control group after treatment(t=3.6057,P<0.01).② hemorheology changes comparison: whole blood viscosity(high-, medium- , low shear), whole blood reduction viscosity, erythrocyte aggregation index, hematocrit in the treatment group were improved obviously after the treatment than before(t=3.356, 13.245, 3.650, 7.443, 9.912, 3.113,P<0.05 orP<0.01). The whole blood viscosity(high-, medium-shea), blood reduction viscosity, erythrocyte aggregation index in the control group were obviously improved than the before(t=2.144, 4.216, 3.287, 3.039, 6.442,P<0.05 orP<0.01). The difference between the two groups were also obvious after the treatment(P<0.05 orP<0.01).Conclusions Cervical traction and manipulation combined with flunarizine can elevate ESOV score, improve hemorheology and therapeutic effect in patients with cervical vertigo.

This paper focuses on the requirements of joint operations under informationization in the future,and system-atically analyzes the characteristics of medical protection with regard to epidemic causes and surveillance,prevention meas-ures,mental health,and nuclear,chemical and biological protection.This paper elaborates on the basic principles of medical protection and raise proposals about health and epidemic protection so as to provide references for health support of PLA during joint operations.

Objective of electroacupuncture(EA) of Alzheimer′s disease(AD) rat learning and memory ability and plasma SOD , MDA content in brain P53 ,P21 expression .Methods The normal 36 SD rats ,were randomly divided into sham operation group , model group and EA group .EA group acupuncture “Baihui” ,“Taixi” ,“Zusanli” treatment ,through the Morris water maze test in rats behavioral changes ,spectrophotometric observation of SOD and MDA in rat plasma levels ;observation of rat brain P53 ,P21 ex-pression by immunofluorescence .Results Compared With the model group ,group EA escape latency ,longer in the third quadrant of the activities of the time ,the number of crossing platform position increased ,decreased the elevated plasma SOD level ,MDA lev-el ,reduce the expression of brain P53 ,P21 ,and the difference was statistically significant (P<0 .01) .Conclusion electro-acupunc-ture treatment can improve the Aβ1-42-induced AD rat spatial learning and memory ability ,may be lowered P53 ,P21 protein ex-pression increase SOD activity and MDA .

Objective To study the effects of miR-130b on the neuronal migration in the developing embryonic mice cortex.Methods Pregnancy E15.5 mice were selected and plasmid of miR-130b was injected into the lateral ventricle of the embryonic brain.Two days after eletroporation,murine embryos were collected and cut into frozon coronal slices,then surveyed the neuronal migration under the fluorescence microscope.Results The neuronal migration rates were higher in miR-130b overexpression embryonic cortex,of which 75.1％ eletroporated neurons migrated into MZ,compared with the 22.1％ in control group.On the contrary,only 7.9％ eletroporated neurons stayed in the VZ/ SVZ in the experimental group,compared with the 69.3％ in control group.Conclusions miR-130b accelerates the neuronal migration in the developing embryonic mice cortex,its regulational role is worth studying.

Objective: To study the effect of volatile oils from Foeniculum Vulgare Mill, anisaldehyde, anethole and water extracts on the percutaneous penetration of 5 fluorouracil. Methods: With Valia Chien horizontal diffusion cell and HPLC method to observe the effect of volatile oils of Foeniculum Vulgare Mill, anisaldehyde, anethole on the percutaneous penetration of 5 fluorouracil. Results: The volatile oils of Foeniculum Vulgare Mill, anethole, anisaldehyde possessed the high promoting action on percutaneous absorption of 5 fluorouracil, and their enhancement ratio are 7.14, 4.17, 9.54, respectively. Conclusion: The volatile oils of Foeniculum Vulgare Mill, anethole, anisaldehyde enhance the skin permeation of 5 fluorouracil effectively.

Microinjoction of thy-rotropin-releasing hormone (TRH) into par-avemricular nucleus (PVN ) obiviously increased gastric motility: frequency of gastric motility change from 3~1 times ? min-1 to 6 ~ 8 times ? min-1. intergastric pressure (IGP) rose from 0. 49 ? 0. 01kPa to 1. 9 1 ? 0. 5kPa. (P

Objective To observe the effects of Donepezil on cognitive function of delyed ephalophthy after acute carbon monoxide poisoning ( DEACMP) .Methods Eighty patients with DEACMP were randomly divided into control group ( 40 cases ) and treatment group ( 40 cases ) .The control group was given treatment of regular medicine, placebo and hyperbaric oxygenation.The treatment group was given treatment of regular medicine, Donepezil and hyperbaric oxygenation.The dose of Donepezil was 5.0 mg per night, and 90 d was a period of treatment.The cognitive function of patients was evaluated respectively by MMSE and Barthel Index rating scale ( BI) .And the results were compared between the two groups.Results Compared with before treatment, the MMSE and BI scores of the two groups after treatment were significantly increased (P<0.05 -0.01).And after the treatment, the MMSE and BI scores of the treatment group were significantly higher than those in the control group (P<0.05-0.01).Conclusion Donepezil can greatly improve the cognitive function of DEACMP patients, it is worthy to be clinical promoted.