Objective To investigate the effective dose of dexmedetomidine on reducing agitation after sevoflurane anesthesia in patients undergoing repair of indirect inguinal hernia .Methods 105 patients ( ASAⅠ-Ⅱ) were randomly assigned into three groups ,35 cases in each group .In the observation group 1 and observation group 2, the patients received intravenous injection of dexmedetomidine 0.15μg/kg and 0.30μg/kg respectively.In the control group,the patients received intravenous injection of 0.9% normal saline solution 2mL before surgery.All patients were induced by 3%sevoflurane and maitained by 1.2%sevoflurane and hiatus sacralis block .During the operation, the BP,HR,SpO2,RR were recorded.At the end of anesthesia,the time to eyes opening (TEO) and agitation of emer-gence were recorded.Results The TEO of the control group,observation group 1,observation group 2 was (8.45 ± 4.02)min,(9.23 ±5.03)min,(10.81 ±4.06)min,respectively,and there were no significant differences among the three groups(all P>0.05).The incidence rate of agitation of the observation group 1 was 20.00%,which was signifi-cantly lower than that in the control group (42.86%) (χ2 =31.42,P<0.05 ),and that of the observation group 2(8.57%) was significantly lower than the control group and observation group 1(χ2 =24.37,7.53,all P<0.05). Conclusion The dose of dexmedetomidine 0.3μg/kg administered after induction of anesthesia can reduce the post-sevoflurane agitation in children and with no adverse effects .

The sorts of harms brought by medical equipment are introduced and the importance of preventing these harms is emphasized.The relationship between the usability and safety of medical equipment is discussed.It is pointed out that the research of usability is necessary to improve equipment safety.Meanwhile,from the perspective of government and industry regulation,it shows that it is crucial to set up the laws and regulations for safety of medical equipment.Finally,it concludes that only if the operation training and day-to-day maintenance and management are strengthened,would the equipment's safety and reliability be ensured.

Objective:To test the reliability and validity of the Behavior Rating Scale of Executive Function(BRIEF) teacher form for school age in China.Methods:A total of 185 children with attention deficit hyperactivity disorder(ADHD),post-tramatic stress disorder(PTSD) or conduct disorder(CD),and 324 normal children were enrolled in this research.Parents of the subjects completed the BRIEF parent form,while teachers of the subjects filled in the BRIEF teacher form and the teacher form of Achenbach child behavior checklist(TRF).Performance-based tests of executive function,including the Stroop,trail-making,digit span and Tower of Hanoi(TOH) were carried out in some controls(n=57) and ADHD subjects(n=32).Results:Test-retest reliability coefficients were 0.65~0.86 and Cronbach ? coefficients were 0.73~0.98.The inhibition subscale and monitor subscale of BRIEF teacher form were significantly correlated with subscale of TRF(r=0.47~0.88,Ps

The status quo of China's Clinical Medical Engineering is analyzed in detail using SWOT,which shows its strength and weakness sufficiently,and forecasts the latent threat from outside.Based on the analysis above,some measures are brought forward for rapid progress of China's Clinical Medical Engineering.

Child ; Consensus ; Disease Management ; Humans ; Pediatrics ; Shock, Septic ; therapy

Antibodies, Viral ; analysis ; Cerebrospinal Fluid ; virology ; Child ; Child, Preschool ; Feces ; virology ; Genotype ; Humans ; Infant ; Meningoencephalitis ; diagnosis ; virology ; Parechovirus ; classification ; genetics ; isolation & purification ; Picornaviridae Infections ; diagnosis ; epidemiology ; virology ; RNA, Viral ; genetics ; Respiratory Tract Infections ; diagnosis ; virology ; Sepsis ; diagnosis ; virology ; Sequence Analysis, DNA

Acute Coronary Syndrome ; diagnostic imaging ; pathology ; Adult ; Aged ; Aged, 80 and over ; Angina Pectoris ; diagnostic imaging ; pathology ; Atherosclerosis ; diagnostic imaging ; pathology ; Female ; Humans ; Male ; Middle Aged ; Ultrasonography, Interventional ; methods ; Young Adult

Although acute respiratory distress syndrome (ARDS) has been the focus of extensive basic science and clinical research over the past 40 years,its pathogenesis is not clear.The therapies for ARDS have been not consensus.In addition to the lung-protective ventilatory strategies,effective pharmacologic therapy for ARDS remains extremely limited and still continue to explore and study.This paper reviews the cunent pharmacotherapies to treat ARDS,including neuromuscular blockers,corticosteroids,neutrophil elastase inhibitor,antioxidants,granulocyte macrophage-colony stimulating factor,β2 adrenergic receptor agonists,pulmonary vasodilators.

The distribution and numbers of SRIF-immunoreactive cell bodies and fibers in normal and castrated rats hypothalamus were studied by PAP immunocytochemistry. The results showed that the positive cell bodies and fibers in periventricular nucleus (PV), suprachiasmatic nucleus (SCN) and paraventricular nucleus (PVN) were more numerous in male than in female. Another marked sexual dimorphism was found in medial preoptic area (MPO) which was filled with dense plexus of varicose immunoreactive fibers in male, while there were low density of stained fibers in female. Orchiectomized rats had fewer number of positive neurons in PV, PVN, SCN and arcuate nucleus (ARN), and lower density of fiber in SCN, ARN, MPO and median eminence than the normal rats. On the contrary, in the ovariectomized rats could find more numerous cell bodies and fibers in these areas. When gonadal steroid was given after gonadectomy, the SRIF neurons became similar to the normal.

This paper is a literature review of impact of comorbidity on the executive function(EF) of patients with attention deficit hyperactivity disorder(ADHD).Over 80% of children and adolescents and 65%-89% of adults with ADHD suffer from one or more additional psychiatric disorders.EF deficits in ADHD of all ages can be demonstrated to be independent of psychiatric comorbidity.The presence of comorbid learning disorder(LD) and mood disorder(MD) appears to increase the EF deficits in ADHD which seems to be decreased by the the presence of comorbid anxiety disorder and oppositional defiant disorder and conduct disorder(ODD/CD).However,the comorbidity of LD,MD,ODD/CD and Tourette syndrome may have no impact on the EF deficits in ADHD.