No abstract available.
Dermatitis, Atopic ; Pyroglyphidae

In this study, the authors attempted to investigate distribution of the house dust mites in Korea on a nationwide scale. Mites were isolated and classified from 211 house dust samples which were collected from 7 urban areas and 3 rural areas. The result were as follows: 1) Nineteen species of mites were identified in this study including 4 new species which were not recorded in Korea. 2) The most frequent house dust mites were Pyroglyphid mites. Among then, Derntatophagoides farinae was found to be dominant species in Korea since this species was more widely distributed and more frequently found than D. pteronyssinus, 3) The occurence rates of Dermatophagoides sp. in the urban areas were higher than that in the rural areas, but vice versa in the occurence rates of other mites accidently found in the dust samples.
Dust* ; Korea ; Mites ; Pyroglyphidae*

No abstract available.
Child* ; Dust* ; Humans ; Lymphocytes* ; Pyroglyphidae*

No abstract available.
Antibody Formation* ; Dust* ; Immunotherapy* ; Pyroglyphidae*

No abstract available.
Humans ; Pyroglyphidae* ; Rhinitis* ; Sublingual Immunotherapy*

PURPOSE: The objective of this research is to provide the indoor environment management education program for the asthma patients and their families and then analyze the effectiveness in education preventing allergic asthma. METHODS: A pre-post single group quasi-experimental design was used to provide an education program about correct indoor environment management to a total of 58 households (29 patient households and 29 normal households). The performance rate of correct indoor environment management procedure, amount of house dust mite antigen, allergy subjective symptoms score and knowledge score about indoor environment management were compared before and after the education to test the effectiveness of the education. RESULTS: Home-visit education in this research had effects in improving subject households' performance rate of indoor environment management procedures, reducing the amount of house dust mite antigen - an important inducing factor of allergy, and reducing perceived subjective symptoms of allergy.
Asthma* ; Education* ; Family Characteristics ; Humans ; Hypersensitivity ; Pyroglyphidae

Studied group includes 42 patients with allergic rhinitis in whole the year by house dust mite. Control group includes 14 healthy, no allergic subjects. In normal person serum specific IgE level was nearly none. The most of allergic rhinitis patients had serum IgE with variois levels. The assay gave the same sensivity and specificity of 85.71%. In 6 patients non-consistent result of the assays was 14.29%. There is a correlation of these 2 assays with a coefficient of r = 6.12
Rhinitis, Allergic, Perennial ; Immunoglobulin E ; Pyroglyphidae

This study was conducted to investigate distribution of the house dust mites in the bedroom of allergic rhinitis patients in Pusan. From July to December 1995, 51 dust samples were drawn from the bedroom of the patients by using electronic vaccum cleaner. House dust mites were isolated from 50mg dust by applying the modified wet sieving method. The results were as follows: 1 Out of a total 49 dust samples(96.1%) were isolated house mites. 2 Total 977 mites were collected and identified the most prevalent house mites was Pyroglypidae mite with 92.2%. Among them D.pteronyssinus was predominant species. 3 In 1gm of the house dust, 100-499 mites were found in 17 samples(33.3%), more then 500 mites in 12 samples (23.6%). 4 The density of Pyoglypidae mite was close associated with the month. 5 The density of house dust mite was not affected by the type of house, region and the relative humidity of the bed room
Busan* ; Dust* ; Humans ; Humidity ; Mites ; Pyroglyphidae* ; Rhinitis*

BACKGROUND: The skin prick test and in vitro allergen-specific IgE assays are commonly used to diagnose atopic diseases. However, there is still a need for comparison of their diagnostic efficiency. Objective and METHOD: To evaluate their clinical efficiency, the results of UniCAP and multiple antigen simultaneous test (MAST) were compared with skin prick test results. After 51 allergic patients completed skin prick test (SPT), serum sample was collected and UniCAP and MAST were performed to determine specific IgE to house dust mite (Dermatophagoides pteronyssinus : Dp and D. farinae. Df). Result : When SPT was used as a reference standard, UniCAP depicted higher sensitivity of 88.8% to Dp IgE and 91.4% to Df - IgE, but lower specificity of 73.3% to Dp IgE and 75.0% to Df - IgE. However, MAST had lower sensitivity of 75.1% to Dp-IgE and 71.4% to Df - IgE, higher specificity of 93.3% to Dp-IgE and 93.7% to Df - IgE. The values of UniCAP and MAST were significantly correlated with the reactivity grade of skin prick test, respectively. Additionally, the response of SPT was not apparently associated with ECP levels. CONCLUSION: These study results may suggest that both UniCAP and MAST are generally feasible for measuring house dust mite - specific IgE and that they are both replicable.
Dust* ; Humans ; Immunoglobulin E* ; Pyroglyphidae* ; Sensitivity and Specificity ; Skin*

PURPOSE: The clinical usefulness of subcutaneous allergen immunotherapy (SCIT) in the treatment of atopic dermatitis (AD) is still controversial. We analyzed the clinical efficacy of SCIT in patients with AD and the clinical characteristics of patients showing a favorable clinical response to the treatment. MATERIALS AND METHODS: Two hundred and fifty one patients with AD sensitized to house dust mite (HDM) were treated by SCIT using HDM extract. The clinical severity of AD was measured using the standardized clinical severity scoring system for AD (SCORAD) at baseline and 12 months. A favorable clinical response to SCIT was defined as a decrease in SCORAD value at 12 months greater than 50% compared to baseline value. Severe AD was defined as a baseline SCORAD value above 50. RESULTS: A favorable clinical response to SCIT was observed in 73.6% of patients. The proportion of patients showing a favorable clinical response to SCIT was significantly higher in patients with severe AD (90.6%) than patients with mild to moderated AD (63.7%) (p<0.001). Patients with severe AD showing a favorable clinical response had a significantly shorter duration of AD (12.3±8.5 years; mean±SD) than patients with severe AD showing no significant clinical response (20.6±10.9 years) (p<0.05) at baseline. CONCLUSION: SCIT could be a clinically useful therapeutic option for patients with severe AD sensitized to HDM. Early initiation of SCIT might provide a favorable clinical outcome in patients with severe AD sensitized to HDM.
Allergens ; Dermatitis, Atopic* ; Desensitization, Immunologic* ; Humans ; Pyroglyphidae ; Treatment Outcome*