1.ТОЛГОЙ ХҮЗҮҮНИЙ БАЙРЛАЛТАЙ ХОРТОЙ ХАВДРЫН МЭС ЗАСАЛ ЭМЧИЛГЭЭНИЙ ДАРААХ БИЧИЛ СУДАС ЗАЛГАН ЧӨЛӨӨТ ДАЛБАН ШИЛЖҮҮЛЭН СУУЛГАСАН ЭРТ ҮЕИЙН ТУРШЛАГА
Denis S ; Gan-Erdene B ; Battsengel B ; Enkhtuul M ; Ariunbaatar G ; Purevdorj G
Innovation 2017;3(3):26-27
BACKGROUND. Head and neck cancers are related group of cancers that involve the oral cavity, pharynx (oropharynx, nasopharynx, hypopharynx), and larynx. Early-stage tumors of the upper aerodigestive tract can be cured; for late-stage disease, prognosis is poor. Nowadays microvascular free tissue transfer surgery performed at high level. Worldwide, this particular kind of operation in head and neck surgical field has become “golden standard” of treatment. Seemingly, plastic and reconstructive surgeons of developed countries widely perform forearm free flap, anteriolateral thigh free flap, fibula free flap, rectus abdominal free flap, latissimusdorsi free flap. We purpose to report our first 121 cases of Microvascular Free Tissue Transfer which had been performed at the head and neck surgical department, NCC of Mongolia.
METHODS. The clinical records of first 121 cases patients who had microvascular reconstruction done between 2011 and 2017 were reviewed. The indications for surgery, choice of flap, duration of surgery and flap survival were noted.
RESULTS. Our study were performed on 121 cases, among them 84.3% flaps were survived, most of defects occurred following cancer resection. Anterolateral thigh and radial forearm flaps were performed commonly for our reconstruction surgery.
CONCLUSION. 84.3% free flap recorded success rate indicates our early experiences. Although the National Medical University do not have postgraduate reconstructive and plastic surgical training, we believe that meticulous planning, careful vessel selection, close flap monitoring as well as improved infrastructural support can lead us to much better success rates of microvascular reconstruction in our country.
2.Genetic variants within the genus echinococcus identified by restriction fragments length polymorphism
Narankhajid M ; Gurbadam A ; Giimaa N ; Purevdorj I ; Munkhtogoo S ; Ouyn-Erdene B ; Tsendjav A ; Ganzorig B ; Sugar S
Mongolian Medical Sciences 2010;153(3):19-23
Background:Echinococcosis is from animals to humans and cause cestode zoonoses. Genetic variations within of echonoccocus and their genotypes may cause a disease as well as can indicate transmission dynamics to human and pets. At present, there are no available data for the typing of echinococcosis isolated in MongoliaMaterials and Methods:A total of 50 human hydatid samples from collected from State Centre on Maternal and Child Health, Oncology Centre of Mongolia. All samples were examined by PCR using cox1. The PCR products with a molecular size of 578 bp were amplified from human hydatid samples. Also we used RFLP method.Results:Genotype and strains of E. multilocularis and Е. granulosus were identified by RFLP. PCR products were digested using Ssp I, Hind III, Bgl II endonucleases. PCR products were digested by Ssp I endonuclease we found E. multilocularis. PCR products were digested by Bgl II endonuclease. Two major bands were seen in human hydatid sample. The bands have molecular weight of 420 and 158 bp respectively. It was infected by E. granulosus G6. Digestion with Hind III revealed two major bands within samples from human hydatids. These bands have molecular weight of 168, 410 bp respectively. These samples were infected by E. granulosus G1. Most of E. granulosus materials obtained from human patients by surgery confirmed the presence of sheep strain G1 (Bowles and McManus, 1993 a & c). In 24 cases of human hydatid echinococcosis in Mongolia sheep strain was found to be infective to humans.Conclusions:1. Echinococcosis caused by E. granulosus, E. multilocularis in human.2. G1, G6 genotypes of E. granulosus found in human hydatids.
3.Determining the prevalence and incidence of the congenital anomalies among infants’ with 0-7 days registered in Mongolia, 2006-2016
Altanzul B ; Davaajargal S ; Purevdorj B ; Bolorchimeg B
Mongolian Medical Sciences 2017;181(3):25-29
Background:
Approximately, 3.2 millions of children are born with congenital anomalies in worldwide annually
which is equal to one case per each 33 live births. As for Mongolia, there are 2.7 congenital
anomalies cases for each 1000 live births on average between 2005 and 2007, however, this
number is increased up to 5.04 or doubled up for each 1000 live births in 2012 urging us to concern more on this public health issue.
Objective:
To determine the prevalence and incidence of the congenital anomalies among infants’ with 0-7
days registered in Mongolia.
Materials and Methods:
This study is conducted through descriptive analyses. Statistical analyses were conducted by using Stata13, MS excel, and ArcGIS software.
Results:
Total 669,579 women who gave a birth and 2,376 children with congenital anomalies data were used in this study between 2006 and 2016 in Mongolia. In 2006, there were 3.88 cases of congenital anomalies for each 1000 live births and this increased up to 6.44 cases by 2016.
Taking into account the incidence of congenital anomalies by the organ systems, abnormality of circulatory systems were 24.5%, cleft lip and palate were 18.1% of the total cases, respectively. By its geographical patterns, the incidence of congenital anomalies were mostly reported in Orkhon, Gobi-Altai, Gobisumber and Tuv provinces while the least cases reported province was Bayan-Ulgii.
Mean maternal age who gave a birth children with congenital anomalies was 28±6.3 which was statistically significant different (p=0.001) than maternal age who gave a normal birth. In addition, there was high incidence of congenital anomalies among the maternal age groups of 35-44 and above 45 years old.
Conclusion
1. Between 2006 and 2016, the incidence of congenital anomalies was increased around 1.7 times it is tended to increase steadily. Particularly, cases of congenital anomalies were occurred in cardiovascular, circulatory system, cleft lip and palates, skeletomuscular system, digestive and nervous systems.
2. Orkhon province had the highest incidence of congenital anomalies in our study. There was significant association (12% more than live births with normal weight) between congenital
anomalies and child live birth with less than 2500 gr in weights. By gender, congenital anomalies were reported dominantly in boys and it was statistically significant. Case of congenital anomalies increases as the age of mother increases.
4. EPIDEMIOLOGIC STUDY OF ORAL AND MAXILLOFACIAL SURGERY PATIENTS IN MONGOLIA
Davaadorj P ; Otgonbileg E ; Bold M ; Odkhuu J ; Purevdorj G ; Denis S ; Ayanga G ; Khuderchuluun CH ; Batbayar B ; Baasanjav N ; Oyunaa CH ; Budmaa S ; Khentii L
Innovation 2015;9(Dentistry):16-20
The purpose of this study was to analyze the epidemiology of oral and maxillofacial surgery patients in Mongolia and advocate guidelines and programs to promote optimal oral health care. A fact-finding epidemiologic study on the patients who visited at Departments of Oral and Maxillofacial Surgery, at National Hospitals at Ulaanbaatar city and Province and other Central hospitals of Mongolian, from Jan to Dec, 2013.Total 12957 patients treated at inpatients care center at the above mentioned national hospitals. From Ulaanbaatar city were 4284 (36%) and from province were 7673 (64%). Patients from province were treated at FCH 69%, NTORC 6.4%, NCC 11.3%, NCMCH 27% and CMAFH 1.8%. Zero to 16 years, 17 to 36 years, 37 to 56 years and 57 or more years old patients were3072 (27.1%), 4224 (34.2%), 3218 (26.9%) and 1412 (11.8%), respectively. Males and females were 6841 (53%), 6090 (47%). Cases of the inpatients were as follows: infectious disease 5971 (49.88), benign tumor 1039 (8.01%), trauma & injury 1799 (15%), salivary gland disease 2.41%, TMJ disease 2.8%, neuralgia and muscle pain 0.8% and others. 5 provinces have no Oral and Maxillofacial Surgeon and patients were referred to other central hospitals or to the Ulaanbaatar city. This study gives a topic of conversation about undergraduate dental education, continuing education and enough specialists in the region.
5.Case report: Kaposi's sarcoma of the larynx and pharynx
Nyamdulam L ; Tamir L ; Tsend-Ayuush A ; Dolgortseren P ; Purevdorj S ; Bilguntur Kh ; Jargalkhuu E ; Bazarmaa Ts ; Munkhbaatar P ; Sayamaa L ; Shijirtuya B ; Khulan Kh ; Amina G ; Bayarmaa T
Mongolian Journal of Health Sciences 2025;87(3):29-34
Background:
A rare angioproliferative condition of the larynx, Kaposhi sarcoma
typically affects the skin. Immunosuppressive treatment following organ
transplantation and human immunodeficiency virus infection are the causes.
Every type of Kaposi sarcoma has human herpesvirus-8. Laryngeal kaposi
sarcoma is uncommon in immunocompromised patients; since its initial identification
in 1965, 18 cases have been documented globally. A CO2 laser-assisted
laryngeal microsurgery is performed through the mouth cavity to remove
tumor when kaposi sarcoma of the larynx obstructs the airway. Case report: A
77-year-old woman complained of hoarseness, dry mouth, odynophagia, and
dysphagia three months prior when she arrived at the Mongolian-Japan Hospital.
Two years ago, she acquired hard, sensitive lumps that were palpable
on her right arm, left ankle, and right thigh. At that time, she was diagnosed
with Kaposiform hemangiodermatitis and treated at the National Center for
Dermatology. HIV test results were negative. Immunohistochemistry: CD31
+/-, CD34 /+/. Using flexible nasopharyngeal endoscopy to get the diagnosis:
There was a mass that was about 1.5–2–5 cm in diameter, bluish in color,
smooth and movable, and spongy and vascular on the larynx, on the nasopharynx,
behind the palatine tonsills, and supraglottic. Surgery: Through the
use of Kleinsasser laryngoscopy and a 0-degree endoscope, pathological tissues
were extracted under general anesthesia using a laryngeal microsurgical
instrument and a laparoscopic bipolar coagulator. The tissues were then sent
for histological evaluation, which revealed Kaposi sarcoma, sarcoma grade 1.
Results of treatment
Pain decreased and quality of life increased following
surgery. Upon nasopharyngeal endoscopy, the vocal cord mobility was normal
and the surgical incision was clean. Conclusion: Kaposi sarcoma is an
extremely uncommon illness. A lower quality of life and further issues can be
avoided with an early diagnosis and suitable therapy. It also needs to be continuously
monitored because it is a potentially repeatable disease.