Objective To investigate the consultative status of patients with Alzheimer Disease (AD), and to evaluate the efficacy and safety of donepezil (Aricept) in the treatment of AD.Methods This survey was initiated by Chinese society of Geriatrics, and was sponsored by Eisai (China) Inc. It was conducted in 60 hospitals of 40 cities in China. The diagnosis of dementia was made according to ICD-10 and DSM-Ⅳ criteria. The cognition, behavior and ability of daily living of the patients were compared before and after 3-month treatment with donepezil. Results A total of 808 dementia patients were recruited. The main reasons for patients' seeing doctors included memory problem (n= 703, 87%), behavioral and psychological symptoms (n= 250, 31%), impairment of ability of daily living (n= 388, 48% ). The disease course was from 9 months to 16 months, and mean disease course was (13.0 ±0. 2) months. Patients mainly sought treatment from neurologist (74 % ),psychiatrist (6 % ) and geriatrics ( 19 %). They received dementia diagnosis at ( 14.4 ± 0.3) months after their dementia symptoms appeared. Treatment with donepezil for three months improved their cognition, ability of daily living and mental condtion (all P＜0.05). The main adverse effects were nausea, vomiting etc. Conclusions In China, the percentage of people with dementia seeking treatment is low. Most people with dementia see doctors when they reach moderate and severe stages,which affects the efficacy of treatment and daily activity of the patients. Treatment with donepezil for 3 months is effective in improving cognition, behavior and activity of daily living.

At present, about 50 million people worldwide suffer from sarcopenia, and the number is expected to reach 500 million by 2050.Sarcopenia in the elderly will be one of the major global health problems in the future.In this article, current research status and progress of the pathogenesis, diagnosis, its correlation with other diseases and treatment of sarcopenia were analyzed.

Objective Geriatric medicine has become an important medical subspecialty,and will have broad prospects for development.By reviewing the brief history of geriatric medicine,it displays its emergence,birth,concept and scope under different background of social civilization and culture between western and eastern countries.Moreover,it presents the development courses of geriatric medicine in terms of clinical medicine,nursing,education,disciplinary development,academic organization,management and innovation among different countries.As the world's population ages,geriatric medicine is facing both great challenges and opportunities.Only by learning the knowledge and experience from the history and renewing ideas,healthcare professionals can promote the comprehensive development of geriatric medicine,which will be full of vigor and vitality.

Objective To analyze the literature distribution and research status of depression in the elderly published in Chinese Medical Association journals.Methods The literatures of elderly depression published in 85 kinds of Chinese Medical Association journals from 2003 to 2012 were collected.The publication year,distribution,content,author,institution and region of these literatures were analyzed.Results From 2003 to 2012,there were 85 articles on depression in the elderly published in 15 kinds of journals of the Chinese Medical Association.These literatures were published mostly in 2011 (18 articles,21.2％),secondly in 2010 (13 articles,15.3％) and 2012 (12 articles,14.1％),which were published mostly in Chinese Journal of Geriatrics (29,34.1％).These articles mainly included basic science,inventory survey,diagnostic methods and clinical treatment strategy,and the most published form was treatise (77 articles,90.6％).The author who published the most articles was YUAN Gui yong from Nanjing (3 articles,3.5％),the institution which published the most articles was People's Hospital of Hainan Province (4 articles,4.7％),and the provinces or cities which published the most articles were Beijing (15 articles,17.6％),Shandong (9 articles,10.6％) and Zhejiang (7 articles,8.2％) by turns.Among the 85 articles,31 articles (36.5％) were supported by foundations.The definition,epidemiology,mechanism,influence factors,clinical characteristics,diagnosis and treatment strategy of elderly depression,and especially secondary depression were well discussed in these literatures.Conclusions The literatures of elderly depression published in Chinese Medical Association journals are insufficient in quantity,and more than half of the literatures are published from 2010 to 2012.The distribution of journals is relatively concentrated,but the distribution of author,institution and region in these articles is dispersed.Secondary depression in the elderly is concerned especially.

Objective To investigate the situation and development of international literatures on geriatrics and gerontology in mainland China.Methods The literatures on geriatrics and gerontology written by mainland Chinese scholars as the first author were selected from Thomson Scientific database in 1979-2011 period.Researches on basic theory,summary reports of clinical practice and reviews were collected.The quantity of published articles,article types,international cooperation research and funding programs,hospital rankings,as well as the 2011 geriatrics professional journals,thesis topic disciplines distribution and high-performance papers were analyzed by Thomson Data Analyzer software.Results From 1979 to 2011,the quantity of literatures written by Chinese scholars as the first author (not including Hong Kong,Macao and Taiwan regions) was 1927,including 1769 research articles,86 reviews,18 editorials,54 letters.Average paper was cited 7.6 times and the average number of article citation was 30.6.International cooperation research articles occupied 379 (19.7 ％).Articles with research sponsorship were 734 (38.1 ％),in which most subject discipline was geriatric and gerontology.Conclusions The development of geriatric medicine in China is rapid.The international scientific and technological cooperation is very extensive.It is important to further improve the world impact of geriatric medicine from China.The development of geriatric medicine in a large,cooperative,comprehensive,interdisciplinary,interagency direction,and the prospective,multicenter,cooperative study need to promote.It is extremely urgent to establish the English version of Chinese journals of geriatrics with a international influence.

Objective To explore the distribution and research status of literatures on Alzheimer disease (AD) published recently,to compare the differences in the research papers on AD between China and foreign countries,and to provide bibliometrics data for Alzheimer disease research.Methods Using bibliometrics methods,the characteristics and contents of Alzheimer disease research documents were analyzed in Pubmed database and Wanfang web by analysis tools.Research status of Alzheimer disease including the type of literatures and journal distribution from 2008 to 2012 was analyzed.Currently hot topics or top high frequency words were emphatically analyzed.Results There were 646 matched literatures for Alzheimer disease retrieved in Chinese core periodicals,and 19 423 literatures in Pubmed database.The articles for clinical study of Alzheimer disease were more than experimental and epidemiologic study among the 646 literatures.The disciplines distribution of AD in Chinese core journals was similar to international journals,mainly including nerves,brain,and geriatrics journals.The domestic research papers on Alzheimer disease were less than 5％ in Pubmed database,and the articles from Chinese journals in Chinese or English edition accounted for only a small proportion of Pubmed database.The recent research direction of Alzheimer disease in China was similar to foreign countries such as amyloid proteins,diagnosis and gene,but foreign research paid more attention to the metabolism,image and the aging mechanism in AD,while in China there were quite a lot of reports in the literatures on cholinergic drugs,tau protein,hippocampus and Chinese herbal treatments.Conclusions The AD-related disciplines distribution in China and foreign country is relatively fixed in recent 5 years.The AD researches carried out in China are close to those in foreign country,but researches on some areas still lag behind.The experimental and epidemiologic study on AD should be strengthen in China.

Objective To analyze the structural,content and language characteristics of English abstract in domestic versus international geriatrics journals in order to promote international exchange in geriatric medicine research in our country.Methods In this paper,we analyzed the characteristics and contents of original articles published in 5 foreign journals (IF＞3.0) from Pubmed database (n=60) and 5 core (the source of statistics) domestic geriatric journals from Wanfang web during recent 3 years (n=61).Results Our survey showed that in the domestic geriatrics journals,the structured abstracts were used with inflexible four-heading and fixed leading words.In foreign geriatrics journals,however,non-structured abstracts were mostly applied in articles on basic research,and structured abstracts primarily appeared in clinical or survey research papers.Compared with foreign geriatrics journals,the shortages or some problems in English abstracts of the domestic geriatrics journals included a short writing,repetition of objective with title,lack of description of research background,improper description of results data,more passive voice,improper use of modal verbs.Conclusions The domestic geriatrics journals should learn the diverse forms of abstracts and content structure from foreign geriatrics journals,strengthen the elaboration of background and highlights,and use active voice in concordance with the international mainstream.

Objective To evaluate the patient's health care demands in communication,diagnosis,treatment and medical counseling of geriatric BPH outpatients in China.Methods A survey study was carried out in 33 medical centers from 11 different cities in China (North:Lanzhou,Beijing,Shenyang; South:Chengdu,Changsha,Wuhan,Jinan,Nanjing,Hangzhou,Shanghai,Guangzhou).2027 BPH outpatients aged (60 years participated in the survey to measure their health care demands using a questionnaire.Results There were 955 cases (47.1％) thinking communication is necessary before inspection items by a doctor,807 (39.8 ％)thinking communication is necessary before determining the treatment program,389 cases(19.2％) thinking respection items by a doctor is necessary,730 cases(36.0％)the treatment program by a doctor is necessary,849 cases (41.9 ％)thinking health guidance on BPH dignosis is necessary,934 cases (46.1 ％)thinking health guidance on BPH treatment is necessary,The multilevel model showed the demands scores data is similarity among the north and the south.And the patients with more severe lower urinary tract symptoms have more demands on communication and medical counseling.Conclusions It is to get better therapy,considering the patient's health care demands.

Objective To analyze the articles published in Chinese Journal of Geriatrics from 2008 to 2012 so as to understand the characteristics of published papers and research progress in geriatric medicine.Methods Based on Wanfang database,bibliometric analysis was conducted to analyze the quantity,types,authors,affiliations,fund support of all the articles published from 2008 to 2012 in Chinese Journal of Geriatrics.Results A total of 1567 papers were published in the journal from 2008 to 2012.The column with the most published papers was clinical research (1008 papers,64.3 ％),followed by experimental researches,reviews and lectures,investigations etc.The discipline with the most articles published in the journal was cardiovascular medicine,followed by surgery,neurology; respiratory etc.1356 authors from 506 affiliations published paper as the first author in the journal during this five years,with the maximal number being 7 papers and the major affiliation being affiliated hospitals of medical colleges (733 papers,49.3 ％).Authors from Beijing,Zhejiang,Jiangsu,Shanghai published more papers than those from other provinces.29.0％ (455papers) of the total papers were supported by fund,among which the majority was provincial fund,followed by national fund,municipal fund,ministry fund and military fund.Conclusions A relatively stable core author group has formed for Chinese Journal of Geriatrics,and the articles are of high quality.Chinese Journal of Geriatrics is one of the highest academic journals in geriatric medicine.