No abstract available.
Hepatitis* ; Polymyositis*

No abstract available.
Anesthesia* ; Humans ; Polymyositis*

No abstract available.
Hepatitis C* ; Interferons* ; Polymyositis*

No abstract available.
Colon, Ascending* ; Polymyositis*

Cardiomyopathies ; etiology ; Humans ; Polymyositis ; complications

No abstract available.
Eosinophils* ; Glomerulonephritis, IGA* ; Humans ; Immunoglobulin A* ; Polymyositis*

Dermatomyositis ; classification ; Humans ; Myositis ; classification ; Polymyositis ; classification

Idiopathic inflammatory myopathy (IIM) is a rare group of autoimmune diseases, characterized by chronic muscle weakness, muscle fatigue and infiltration of single nuclear cells in skeletal muscle. Its subtypes include dermatomyositis (DM), polymyositis (PM), inclusion body myositis (IBM) and immune-mediated necrotizing myositis (IMNM), and the most common subtypes are DM and PM. PM is an autoimmune disease mainly manifested by muscle damage. When the skin is involved, it is called DM. The incidence of IIM was relatively low, which was 1.16-19 per million people/year, but the mortality was high and the prognosis was poor. The pathogenesis of IIM is still unclear. Previous studies suggest that both immune and non-immune mechanisms are involved in its pathogenesis, especially cellular and humoral immunity. In recent years, researchers have conducted a number of studies on the pathogenesis of IIM, especially in the study of DM/PM with the application of high-throughput biometrics. Epigenetics is a discipline that refers to the genetic phenomena of DNA methylation spectrum, chromatin structure state and gene expression spectrum transferred between cells without any changes in DNA sequence, including DNA methylation, chromatin modification and non-coding RNA changes. A large number of studies have shown that epigenetic modification plays an important role in many diseases, especially in cancer. Recent studies have also found a series of epigenetic markers related to the occurrence and development of DM/PM, mainly in the aspect of non-coding RNA changes, such as miR-10a, miR-206, etc. And there has also been some research on DNA methylation. However, no studies have been reported on whether chromatin modification is involved in the pathogenesis of DM/PM. The pathogenesis of DM/PM is complex and diverse. With the development of research, certain microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) may become biological markers for the early diagnosis of DM/PM. Therefore, this paper mainly expounds the research progress of the biomarkers of DM/PM from the aspect of epigenetics.
Biomarkers ; Dermatomyositis ; Humans ; MicroRNAs ; Muscle, Skeletal ; Polymyositis

Ataxic sensory neuropathy combined with proximal skeletal myopathy is a rare neurologic manifestation in Sjogren's syndrome. The myopathy may be either a form of polymyositis or an immune-mediated neuropathy with muscle involvement. We report a case of primary Sjogren's syndrome with ataxic sensory neuropathy and proximal skeletal myopathy that was proven to be polymyositis with immunohistochemical staining using a mononoclonal antibody.
Muscles ; Muscular Diseases ; Neurologic Manifestations ; Polymyositis ; Sjogren's Syndrome

Dematomyositis is an inflammatory cutaneo-muscular disease of unknown etiology, characterized by symmetrical proximal muscle weakness and typical dermatologic manifestation. Association with systemic maligmancy has been reported in many literatures, but the relationship of dermatomyositis to internal malignancy remains controversial. In Korea, several cases of dermatomyositis or polymyositis associated with malignant neoplasm were reported. Dermatomyositis or polymyositis associated with primary hepatoma has not been reported, Recently authors experienced a patient with dermatomyositis associated with primary hepatoma, and present the case with review of literatures. This may be the first report in Korea.
Carcinoma, Hepatocellular* ; Dermatomyositis ; Humans ; Korea ; Muscle Weakness ; Polymyositis