No abstract available.
Poliomyelitis*

The results of the basic immunization of 3 doses of oral poliomyelitis vaccines for infant and boost immunization of 2 doses of oral poliomyelitis vaccine during 1993-1997 have shown that the poliomyelitis was significant reduced from 152 cases in 1993 to no case in 1998. The last case of poliomyelitis occurred in Phu yen province in 19th January 1997. In 2000, the poliomyelitis was eradicated in Vietnam. However, in order to prevent from returning the disease
Poliomyelitis ; Achievement

Our study is aimed to access polio situation and the surveillance activities of AFP/polio cases in Northern Vietnam from 1992 to 1997. Results showed that due to the quality of the regular and sentinel surveillance improved and the polio vaccination coverage sustained (over 90% for several years), the morbidity of polio has been decreased. There were 146 confirmed cases and 35 wild polio cases in 1992 and up to 1997, there were only 3 confirmed polio cases, none of wild polio cases have been reported since 1994.
Poliomyelitis ; Epidemiology

Data were collected from the Enlarged Immunization Program and the Poliomyelitis Eradication Program (1992-1999), also including inquiry forms and guidelines for detecting, investigating, and processing by Epi-Info. Results shown the epidemic was spread in prevailing of rural population (79.3%), under 5 years old children accounted for 87.9% of cases of poliomyelitis. The outbreaks occurred all around the year with the peak on March, April, May and September, October. Wild virus of the type 1 plays the main role in 97.8% of cases
Poliomyelitis ; Epidemiology

No Abstract Available.
Humans ; Poliomyelitis*

Non - RIMAPREC test carried on 14 single harvests of polyomyelitis vaccine type 3 produced in the year 2002 in Hanoi Centre of Sabin vaccine showed that no DNA mutant was detected. WHO criteria on safety were met
Poliomyelitis ; Vaccines ; standards

In 2004, 10 poliovirus strains were isolated from 4 acute flaccid paralytic cases (AFP). All these poliovirus strains were confirmed as Sabin-like strains. 66 other non-polio enterovirus strains were also isolated including 29 echoviruses, coxsackie B viruses and 30 untyped enteroviruses. These virus strains were isolated from 489 stool specimens of 245 AFP cases. The results confirmed the free status of the stable sustaining poliomyelitis in Viet nam.
Viruses ; Enterovirus ; Poliomyelitis, Patients

In the period from 2000 to 2004, 393 non-polio enterovirus strains were isolated containing 140 Echoviruses, 35 coxsackie viruses and 218 untyped enteroviruses. These viral strains were isolated from 2,232 stool specimens of 1,116 patients with acute flaccid paralysis. 32 poliovirus isolates were all Sabin viruses. The result confirmed the free status of the sustaining of poliomyelitis between 2000 and 2004 in Vietnam.
Enterovirus ; Poliomyelitis, Patients

A study on the establishment of the effective standard for the national standard samples of vaccine of single vaccine type 1, 2 and 3 and triple vaccine (Sabin) produced in Vietnam was carried out. The sesults have shown that the National standard sample had a high unified and stable properties that meet the requirement of the world health organization (WHO). The National standard sample were used to evaluate the quality of sabin vaccine produced in Vietnam which showed that 450 batches (100%) sabin vaccine produced in the scientific center for the vaccine production during 1995-1999 obtained the standard of WHO.
Poliomyelitis ; Poliovirus Vaccine, Oral

During the period from 1993 to 1997, 126 poliovirus positive cases from samples of 1.098 acute flaccid paralysis patients of all provinces in the Northern region and 5 others in the Central region of Viet Nam have been identified. Among them 97 cases were caused by poliovirus type 1, 5 by type 2, 10 by type 3, 11 were identified as a multitype infection and 3 cases were the combination of poliovirus and enteroviruses. The antigenic properties of the poliovirus strains isolated have been studied using monoclonal antibody and polymerase chain reaction. The results showed that, 53 strains of poliovirus type 1 were identified as the wild-type virus, the rest were of Sabin-type virus. The wild poliovirus strains were then classified in to 2 groups by polymerase chain reaction - restriction fragment length polymorphism and sequencing methods. No case of wild type virus was isolated since 1994.
Poliomyelitis ; Polioviruses ; Paralysis