No abstract available.
Poliomyelitis*

The results of the basic immunization of 3 doses of oral poliomyelitis vaccines for infant and boost immunization of 2 doses of oral poliomyelitis vaccine during 1993-1997 have shown that the poliomyelitis was significant reduced from 152 cases in 1993 to no case in 1998. The last case of poliomyelitis occurred in Phu yen province in 19th January 1997. In 2000, the poliomyelitis was eradicated in Vietnam. However, in order to prevent from returning the disease
Poliomyelitis ; Achievement

Our study is aimed to access polio situation and the surveillance activities of AFP/polio cases in Northern Vietnam from 1992 to 1997. Results showed that due to the quality of the regular and sentinel surveillance improved and the polio vaccination coverage sustained (over 90% for several years), the morbidity of polio has been decreased. There were 146 confirmed cases and 35 wild polio cases in 1992 and up to 1997, there were only 3 confirmed polio cases, none of wild polio cases have been reported since 1994.
Poliomyelitis ; Epidemiology

Data were collected from the Enlarged Immunization Program and the Poliomyelitis Eradication Program (1992-1999), also including inquiry forms and guidelines for detecting, investigating, and processing by Epi-Info. Results shown the epidemic was spread in prevailing of rural population (79.3%), under 5 years old children accounted for 87.9% of cases of poliomyelitis. The outbreaks occurred all around the year with the peak on March, April, May and September, October. Wild virus of the type 1 plays the main role in 97.8% of cases
Poliomyelitis ; Epidemiology

No Abstract Available.
Humans ; Poliomyelitis*

A study was conducted to test the sterility of 416 final lots of OPV produced by POLIOVAC, Vietnam from 1994 to 2003 in thioglycolate and soybean casein digest media under the standard operating procedure. The study results showed that all the tested lots (461/461 = 100%) had met the requirements for sterility
Infertility ; Poliomyelitis ; Antigens, Bacterial

Non - RIMAPREC test carried on 14 single harvests of polyomyelitis vaccine type 3 produced in the year 2002 in Hanoi Centre of Sabin vaccine showed that no DNA mutant was detected. WHO criteria on safety were met
Poliomyelitis ; Vaccines ; standards

A study on the establishment of the effective standard for the national standard samples of vaccine of single vaccine type 1, 2 and 3 and triple vaccine (Sabin) produced in Vietnam was carried out. The sesults have shown that the National standard sample had a high unified and stable properties that meet the requirement of the world health organization (WHO). The National standard sample were used to evaluate the quality of sabin vaccine produced in Vietnam which showed that 450 batches (100%) sabin vaccine produced in the scientific center for the vaccine production during 1995-1999 obtained the standard of WHO.
Poliomyelitis ; Poliovirus Vaccine, Oral

During the period from 1993 to 1997, 126 poliovirus positive cases from samples of 1.098 acute flaccid paralysis patients of all provinces in the Northern region and 5 others in the Central region of Viet Nam have been identified. Among them 97 cases were caused by poliovirus type 1, 5 by type 2, 10 by type 3, 11 were identified as a multitype infection and 3 cases were the combination of poliovirus and enteroviruses. The antigenic properties of the poliovirus strains isolated have been studied using monoclonal antibody and polymerase chain reaction. The results showed that, 53 strains of poliovirus type 1 were identified as the wild-type virus, the rest were of Sabin-type virus. The wild poliovirus strains were then classified in to 2 groups by polymerase chain reaction - restriction fragment length polymorphism and sequencing methods. No case of wild type virus was isolated since 1994.
Poliomyelitis ; Polioviruses ; Paralysis

After 5 years, since 1993, the strategies for polio eradication have been well implemented. Coverage of routine immunization with 3 doses of OPV to children under 1 year of age has always been maintained higher than 90%. Coverage of supplementary immunization with 2 doses of OPV to children under 5 years of age during the NIDs has been achieved greater than 98%, surveillance of all the acute flaccid paralysis cases with collection of 2 adequate stool specimens for the identification of wild poliovirus. The results of the surveillance show that wild poliovirus cases have disappeared, decreasing from 152 cases in 1993 to 0 cases in 1998. The last cases of wild poliovirus identified in Phu Yen province of Central region had the date of onset on the 29th January 1997.
Poliomyelitis ; Child ; Poliovirus