By synthesizing and analysing poisoning analyses from 1996 to 2000 at Hai Phong Viet Tiep Hospital found an increasing incidence of insecticide and raticide poisons. Incidence of insecticide and raticide was 21.18% in 1996, in which raticide rate was 5.08%, raticide rate was 20.11% in 2000, there were a noticeable rate of raticide poisons without knowing the origin of the raticide in chinese (called chinese raticide). The poisoning analyses played a considerable role in giving first aid for poisons in general and for insecticide and raticide poisons in particilar
Insecticides ; Poisons ; Epidemiology

Naturenz, a mixture of plant oxydase, protease, natural anti-oxydants, aminoacids and vitamins has been used for treating dioxin exposed patients. This preparation can improve the patients status. An icrease of SH-group, of total hem content and of anilin hydroxylase acitivty in blood, a decreasing of urine urobilinogen was notified on patients after administration
Dioxins ; Chemistry ; Poisons

There was no acute toxic on rabbit's bodies after ingested activated charcoal suspension (1g/kg and 1,2g/kg body weight). Circulating blood cells and the function of kidney and liver were not changed after 7 days ingested activated charcoals
Animal Experimentation ; Poisoning ; Poisons

From 1997 to 2000, 22 children aged 5-15 (11 boys, 11 girls) were admitted in emergency department of Pediatric Institute due to intoxincation of Moc dieu. Only 9/17 (52.9%) of subjects described exactly the toxic plant. The most significant clinical signs are vomit and fatigue (100%), jaundice (100%). Hemorrhage of various degree around the orbit (17/17) and the sclera, 15/17 cases of edema and aliogourine. This is a life threatening intoxication in mild and mode rate cases, the prognos is of treatment at the institute is good, only 1 death
Child ; Poisoning ; Poisons

Beta-fluoroethylacetate has been extensively used as the rodenticide in Korea. In some patients with acute poisoning, beta-fluoroethylacetate caused cerebellar dysfunction as a single and persistent neurologic sequela after a period of an acute neurological disorder which is characterized by mental deterioration, seizures, and respiratory failure. But there has been no report of pathological findings to explain neurological deficit. We tried to verify the histologic changes of the central nervous systems in beta-fluoroethylacetate poisoned rats. Silver staining(Gallyas) was used to evaluate the histology. In acute intoxication experiment with LD50(7mg/Kg), beta-fluoroethylacetate elicited acute onset of consciousness deterioration, generalized tonic-clonic seizures and large amplitude tremulous activity involving whole body with full recovery after 24 hours. There was no discernible pathologic change in CNS in acutely poisoned rats. However, when poisoned with sublethal dose(5mg/Kg) daily for five days, a moderate degree of nerve cell degeneration was found selectively in dentate nucleus, Purkinie cell layer, vestibulo-cochlear nucleus and striatum. This change was not seen in hippocampus, cerebral cortex or cerebellar cortex. These findings were well correlated with the previous reports of selective pathology in human 5-FU intoxication cases. Our preliminary results suggest that beta-fluoroethylacetate, a kind of cellular metabolism inhibitor may induce selective neuropathology mainly involving cerebellar output pathway in rats.
Humans ; Rats ; Animals ; Poisons

Calibration ; Humans ; Poisons ; urine

The exact of Zingiber officinale Rosc (ZO) and ZO-Typhonium divaricatum Decne (TD) complex were used to evaluate its antiemetic effect and acute toxicity on young dogs and mice. The results showed that the extract of ZO in dose of 0.1 g/kg body weigh, ZO 0.1 g and TD 0.12 g complex/kg body weigh per oral route have antiemetic effect in comparison with control one. Both of raw and pure TD extracts have equal effect. ZO and TD have a quite low acute toxicity
Animal Experimentation ; Poisons ; Pharmaceutical Preparations

Herbicides ; poisoning ; Humans ; Occupational Exposure ; Poisons

OBJECTIVES: To retrospectively analyze homicide cases of death after injection and provide reference for forensic identification. METHODS: Six homicide cases of death after injection which were investigated by the Criminal Investigation Team of Shanghai Public Security Bureau were collected and analyzed, including case situation, scene investigation, autopsy and other materials. RESULTS: The 6 cases were premeditated crimes, 5 cases took place in private spaces, and 5 cases involved the victims approached by suspects' decoy. There were no obvious abnormalities at the scene of the 6 cases. In 6 cases, the victim's body surface injury was mild or no, lividity color was abnormal, and the needlestick injury showed different manifestations from conventional medical measures. CONCLUSIONS Death after injection is a highly concealed crime and easy to be ignored. For the suspected injection injury found in autopsy, it is necessary to carefully examine, identify and analyze, be alert to the situation of injecting poison (drug) and do a good job in evidence fixation and material extraction.
Autopsy ; China/epidemiology* ; Homicide ; Poisons ; Retrospective Studies

OBJECTIVETo investigate the characteristics of acute poisonings caused by various poisons in Guangxi, China.

METHODSA retrospective investigation was performed in 5859 cases of acute poisonings who were admitted to 63 hospitals in 11 cities, as well as 531 types of poisons involved. The poisons were categorized into 6 groups; each group of cases was stratified by the rural or urban settings, frequency of poisoning, and cause of poisoning to analyze the numbers of cases and constituent ratios.

RESULTSMost types of poisons (68.74%) belonged to drugs (217 types) and pesticides (148 types). Most cases of poisonings (61.63%) were caused by pesticides (n = 2547) and chemicals (n = 1064). Pesticides, poisons of plant origins, and poisons of animal origins were responsible for most of the cases in rural settings; 88.46%, 79.10%, and 66.74% of the cases of these poison categories happened in rural settings. Chemicals, drugs, and other poisons were responsible for most of the cases in urban settings; 70.20%, 61.74%, and 63.73% of the cases of these poison categories happened in urban settings. The numbers of cases in 5-year-poisoning groups were the highest in all categories of poisons, accounting for 85.24%, 88.57%, 55.16%, 70.79%, 68.36%, and 66.44%of cases of respective categories. Most cases of poisonings by chemicals, poisons of animal origin, and other poisons were accident-related (86.24%, 72.66%, and 46.71%of the poison categories). Most cases of poisonings by pesticides and drugs were suicide-related (59.39% and 33.52% of the poison categories). Most cases by poisons of plant origin were caused by accidental ingestion (70.36% of the poison category).

CONCLUSIONMost of the acute poisonings in Guangxi area are caused by pesticides and chemicals; the most common causes of poisoning are accidents, accidental ingestion, and suicide. There are significant differences in the causes of acute poisonings between the urban and rural settings.

Accidents ; China ; epidemiology ; Humans ; Pesticides ; poisoning ; Poisoning ; epidemiology ; Poisons ; analysis ; Retrospective Studies