No abstract available.
Animals ; Mice* ; Plaque, Atherosclerotic*

Humans ; PPAR gamma ; Plaque, Atherosclerotic

Cytophagocytosis ; Humans ; Plaque, Atherosclerotic ; physiopathology

Diagnostic Imaging ; trends ; Humans ; Plaque, Atherosclerotic ; diagnosis

To solve the problem of stent malapposition of intravascular stents, explore the design method of intravascular body-fitted stent structure and to establish an objective apposition evaluation method, the support and apposition performance of body-fitted stent in the stenotic vessels with different degrees of calcified plaque were simulated and analyzed. The traditional tube-mesh-like stent model was constructed by using computational aided design tool SolidWorks, and based on this model, the body-fitted stent model was designed by means of projection algorithm. Abaqus was used to simulate the crimping-expansion-recoil process of the two stents in the stenotic vessel with incompletely calcified plaque and completely calcified plaque respectively. A comprehensive method for apposition evaluation was proposed considering three aspects such as separation distance, fraction of non-contact area and residual volume. Compared with the traditional stent, the separation distances of the body-fitted stent in the incompletely calcified plaque model and the completely calcified plaque model were decreased by 21.5% and 22.0% respectively, the fractions of non-contact areas were decreased by 11.3% and 11.1% respectively, and the residual volumes were decreased by 93.1% and 92.5% respectively. The body-fitted stent improved the apposition performance and was effective in both incompletely and completely calcified plaque models. The established apposition performance evaluation method of stent considered more geometric factors, and the results were more comprehensive and objective.
Constriction, Pathologic/surgery* ; Humans ; Plaque, Atherosclerotic ; Stents

Endothelium ; Epithelial-Mesenchymal Transition ; Humans ; Plaque, Atherosclerotic

The cerebral aneurysm 'clip scissoring' phenomenon resulting from clip blade twisting is an unpredictable surgical complication. Additionally, incomplete clipping resulting from the presence of an atherosclerotic wall in the neck of the aneurysm can also cause unforeseen problems. Here, the authors present an unusual case of incomplete clipping of a large, atheromatous aneurysm resulting from clip scissoring, which was treated with additional endovascular coiling.
Aneurysm* ; Intracranial Aneurysm ; Neck ; Plaque, Atherosclerotic ; Surgical Instruments ; Treatment Failure

An embolus is a detached intravasclar solid, liquid, or gaseous mass that is carried by the blood to a site distant from its point of origin. Virtually 90% of all emboli arise in thrombi (thromboembolism). Rare forms of emboli include fragments of bone or bone marrow, atheromatous debris from ruptured atherosclerotic plaques, droplets of fat, bits of tumor, foreign bodies such as bullets, and bubbles of air of nitrogen. Lung embolism is the disease condition caused by pulmonary vasculature obstruction with various kinds of material mentioned above.
Bone Marrow ; Embolism* ; Foreign Bodies ; Lung* ; Nitrogen ; Plaque, Atherosclerotic

Humans ; Microvessels ; Neovascularization, Pathologic ; Neovascularization, Physiologic ; Plaque, Atherosclerotic ; pathology

Animals ; Atherosclerosis ; diet therapy ; physiopathology ; Humans ; Plaque, Atherosclerotic ; drug therapy