Hydatidiform mole (H mole) is a rare complication of pregnancy, characterized by an atypical trophoblastic proliferation and swelling of the chorionic villi, with or without a live fetus. A clinical diagnosis of H mole is confirmed by significantly high serum beta-hCG levels and/or the presence of characteristic sonographic and histopathologic findings. Differentiation between the two types—complete or partial—is important, since complete moles pose a higher risk for malignancy. An H mole can be further complicated by the presence of a coexisting live fetus. Complete molar pregnancy with a coexisting live fetus has an incidence of only 1 in 22,000 to 100,000 pregnancies. Termination of pregnancy is usually considered, especially when a high risk of choriocarcinoma and maternal prenatal complications are present. We present the case of a 27-year-old female diagnosed as having a complete H mole with a coexisting live fetus. We terminated the pregnancy due to profuse vaginal bleeding that could cause maternal and fetal compromise.
Choriocarcinoma ; Placental mesenchymal dysplasia ; Methotrexate ; Gestational Trophoblastic Disease ; Hydatidiform mole