Objective To evaluate the safety and feasibility of totally laparoscopic radical distal gastrectomy (TLDG)and intracorporeal gastroduodenostomy using laparoscopic linear staplers in gastric cancer patients.Methods Clinical data were reviewed on the perioperative outcomes of 17 gastric cancer patients who received totally laparoscopic distal gastrectomy and intracorporeal gastroduodenostomy using endoscopic linear staplers from June 2012 to June 2013 at Department of General Surgery,Lishui Central Hospital.Results The mean operation time were (2.6 ± 0.4) h,TLDG with deltashaped anastomosis was successfully carried out in all the patients except for 1 case who was converted to open surgery.There was no serious complication and no death in this series.The postoperative pain in TLDG was less than laparoscopy assisted distal gastrectomy.Conclusions Totally laparoscopic distal gastrectomy and intracorporeal gastroduodenostomy using endoscopic linear staplers is a new method with high safety and feasibility.

Objective:To explore the association between serum 25-hydroxyvitamin D [25-(OH)D] and high-sensitivity C reactive protein (hs-CRP) levels in health check-ups population.Methods:A total of 746 patients who underwent health check-ups at an enterprise unit in Hefei city were selected as the study subjects with an average age of (47.2±15.6) years and 489 males, accounting for 65.5%. Demographical and disease information was collected through questionnaires. Serum 25-(OH)D and hs-CRP levels were measured. The subjects were divided into three groups according to the 25-(OH)D level: non-deficient group (≥50 nmol/L), deficient group (25 nmol/L to 49.9 nmol/L), severely deficient group (<25 nmol/L). C-reactive protein was divided into normal group and high value group by 75% percentile. Multivariate logistic regression was used to analyze the relationship between 25-(OH)D and hs-CRP levels.Results:The proportions of high CRP levels in the severely deficient, deficient, and non-deficient groups were 29.8%, 26.4%, and 17.0%, respectively, and the difference was statistically significant (χ2=6.471， P<0.05). Logistic regression analysis showed that, compared with the non-deficient group of 25-(OH)D, the odds ratios values (95% CI) of the high values of hs-CRP in the deficient group and the severely deficient group of 25-(OH)D were 1.851(1.122 to 3.053) and 2.369(1.227 to 4.573), respectively. Conclusions:Serum 25-(OH)D level is a risk factor for hs-CRP in adults. Nutritional intervention in vitamin D deficient population may be beneficial to reduce the level of inflammation.

Animals ; Mice ; Chlamydia muridarum ; Mice, Inbred BALB C ; Antigens, Bacterial ; Chlamydia Infections