A study the quantitative measurement of DNA content in 3 normal lacrimal glands, 18 pleo-morphie adcnomas and 21 lacrimal gland carcinomas was carried out by flow eytometry. The results showed that pleomorphie adenomas still had the characteristics of DNA content of the normal diploid lacrimal gland cells. The significant increase of DNA index (DI) in pleomorphie adenomas might mean malignant transformation. DNA content of malignant tumor increased evidently and its aneuploid ratio was higher than in pleomorphic adenomas (76.2% VS 16.8%) (P

Adult ; Female ; Fluorides ; adverse effects ; Fluorine ; urine ; Humans ; Hydroxyproline ; urine ; Male ; Middle Aged ; Occupational Exposure ; adverse effects ; Young Adult

Osteopontin (OPN), a phosphorylated and glycosylated protein, is a prominent matricellular component of the extracellular matrix of mineralized tissues of bones and teeth, in which they can regulate the formation and growth of hydroxyapatite crystals and influence a variety of cell activities. Recent studies have reported that the expression of OPN is not only correlated with bone formation and bone resorption but also with tumor aggression and metastasis in several types of human cancer, and OPN is even considered to be an index for the diagnosis and prognosis of tumor. The roles of OPN in angiogenesis were also reviewed.

Objective To investigate the effect of small interfering RNA(siRNA)-expressing plasmid targeting connective tissue growth factor(CTGF) on the expressions of its mRNA and protein in cultured human keloid fibroblasts(hKFs).Methods Constructed siRNA-expressing plasmids targeting CTGF were transfected into hKFs by Dosper package.Then the transfected cells were treated with transforming growth factor 1(TGF-?1,10 ng/ml).Normal hKFs cells and those with TGF-?1 treatment served as normal control and control groups respectively.The expression level of CTGF mRNA and protein were detected by real-time fluorescent quantitative PCR(RQ-PCR) and Western blotting respectively.Results The expression level of CTGF mRNA was only 56.6% of that of the normal control(P

This paper introduces the structure, components, function and technical design of the multi -physiological information system, which can not only collect but also register and check parameters. The parameters acquired by the system include electrocardiogram, blood pressure, oxygen saturation and pulse.

Objective To provide scientific basis for formulating National Standard Method for determination of 1,1_dichloroethene in water. Methods The method of head space gas chromatography was established in this assay. Results This method revealed good seperating efficiency and good linear relationship (r=0.9995,n=6). The detection limit was 0.2 ?g/L. The recovery rates of the blank drinking water samples to which was added standard solution containing 10, 20 and 40 ?g/L 1,1_dichloroethene respectively were 108%, 101% and 97% respectively, their related standard deviations were 4.6%, 4.2% and 2.8% respectively. Under the similar procedure as above, the recovery rates of the blank source water samples, added with standard solution containing 10, 20 and 40 ?g/L respectively, were 92%, 94% and 97%, their related standard deviations were 7.0%, 5.0% and 3.3% respectively. Conclusion This method was simple, convenient and effective. The levels of recovery rates and precision of this method all accorded with the requirements of the determination of 1,1_dichloroethene in water.

Small cell lung cancer ( SCLC ) is one common type of lung cancer in China. No remarkable progress has been made in systemic therapy for SCLC since the 90’ s. However, there are some advances in radiotherapy ( RT) for SCLC, which make it possible to improve treatment outcomes of SCLC. Those advances are mainly made in thoracic RT and prophylactic cranial irradiation for extensive?stage SCLC, radiation dose and technology of thoracic RT for limited?stage SCLC, and significance of prophylactic cranial irradiation for early?stage SCLC. The paper reviews the research advances in the East and West to provide some help and references for readers.

Objective Perioperative fluid therapy has always been the most basic and important measure to maintain the stability of patients'cyclic system.Colloid and crystalloid,as common perioperative fluid,play different roles in clinical application due to the different molecular sizes.In the recent years,besides their contribution to maintain the stability of cyclic system,scientists have begun to pay attention to the effect on coagulation,especially their comparison.This paper mainly discusses the study status of the influence on coagulation produced by different liquids.

Early detection and timely treatment hold the key to cure retinopathy of prematurity (ROP).ROP screening is carried out unevenly in China.Examination equipments and personnel experiences are the major factors to constraint ROP screening.In addition to strengthening personnel training,it is necessary to establish a standard guideline and pipeline for ROP consultation and referral. Laser photocoagulation and cryotherapy are the first options for the threshold ROP and Type 1 pre-threshold ROP.Scleral buckling or vitrectomy is needed for advanced ROP when retinal detachment occurs. The clinical efficacy of intravitreal injection of bevacizumab (an anti-vascular endothelial growth factor monoclonal antibody) for severe ROP is encouraging,but needs further verification.Genetic interference and stem cell therapy will be the prosperous futures in the treatment of ROP.The screening and treatment of ROP in China is becoming more common and improved,but it is still a long way to go considering the huge population of China.