1.The significance of DNA content measurement in clinical diagnose of lacrimal epithelial turnout
Ophthalmology in China 1993;0(03):-
A study the quantitative measurement of DNA content in 3 normal lacrimal glands, 18 pleo-morphie adcnomas and 21 lacrimal gland carcinomas was carried out by flow eytometry. The results showed that pleomorphie adenomas still had the characteristics of DNA content of the normal diploid lacrimal gland cells. The significant increase of DNA index (DI) in pleomorphie adenomas might mean malignant transformation. DNA content of malignant tumor increased evidently and its aneuploid ratio was higher than in pleomorphic adenomas (76.2% VS 16.8%) (P
2.Significance of urine hydroxyproline and urine fluorine of workers exposure to fluorides.
Chinese Journal of Industrial Hygiene and Occupational Diseases 2008;26(8):464-464
Adult
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Female
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Fluorides
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adverse effects
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Fluorine
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urine
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Humans
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Hydroxyproline
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urine
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Male
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Middle Aged
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Occupational Exposure
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adverse effects
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Young Adult
5.Thrombospondin-1 in cancer
Journal of International Oncology 2011;38(11):823-826
Thrombospondin-1 expresses in a variety of tumors and induces endothelial cell apoptosis,thus inhibits tumor angiogenesis and prevents tumor growth.It function domain ( Type I sequence):3TSR,retaines the function of inhibit angiogenesis,has the certain practical significance in clinical cancer treatment.
6.Analysis of Anion Gap in Premature Suffered from Hyperbilirubinemia
Chinese Journal of Primary Medicine and Pharmacy 2012;(22):3379-3380
Objective To investigate the changes of the anion gap(AG)in the premature suffered from hyperbilirubinemia,to provide the basis for treatment.Methods The serum electrolyte,the renal function and the liver function in 94 premature babies suffered from hyperbilirubinemia were tested,and then calculated the value of AG,while the arterial blood gas analyses were done in 36 cases.Results 44 cases had high AG(46.81%),44 cases had normal AG(46.81%)and 6 cases had low AG(6.38%).The increase of AG was directly proportional to the concentration of Na+in blood,while was inversely proportion to the concentration of HCO3-.There was no close relationship between the AG and BUN,Scr in the serum.Conclusion The incidence rate of metabolic acidosis poisoning was high in premature suffered from hyperbilirubinemia with high AG,so the routine test of blood electrolyte,renal function and arterial blood gas should be done.Calculate the value of AG to guide the treatment,and to avoid correcting the acid by the alkali blindly.
7.The influence of perioperative fluid therapy on coagulation
Chinese Journal of Primary Medicine and Pharmacy 2016;23(9):1428-1431
Objective Perioperative fluid therapy has always been the most basic and important measure to maintain the stability of patients'cyclic system.Colloid and crystalloid,as common perioperative fluid,play different roles in clinical application due to the different molecular sizes.In the recent years,besides their contribution to maintain the stability of cyclic system,scientists have begun to pay attention to the effect on coagulation,especially their comparison.This paper mainly discusses the study status of the influence on coagulation produced by different liquids.
8.Research progress on early diagnosis of primary open angle glaucoma
International Eye Science 2016;16(7):1287-1290
Glaucoma is a progressive optic nerve disease, it can cause structural changes of the optic nerve, resulting in irreversible damage of visual function. Early diagnosis is the key to treat the disease at an early stage to stop or delay the progression of visual functional defects. New technologies, including optic nerve and nerve fiber layer structural tests and visual functional tests, increased the diagnosis rate of primary open angle glaucoma (POAG) at an early stage.
9.New progress in the study of anti influenza drugs in the study of influenza virus infection
Chinese Journal of Biochemical Pharmaceutics 2017;37(5):444-448
The antiviral drugs can quickly and directly inhibit influenza virus infection, at present, for influenza virus and replication proteins conserved sites of drugs is the main methods of influenza virus resistance;secondly, traditional Chinese medicine treatment of influenza virus also has an important role;in addition, new technology especially small RNAs mediated RNA interference (RNAi), because of its is efficient, specific and rapid, has become one of the candidate methods for antiviral therapy.
10.Analysis of dynamic change of the blood electrolyte in 343 cases with asphyixtal neonates
Chinese Journal of Primary Medicine and Pharmacy 2010;17(1):40-41
Objective To analyse the change of the blood serum electrolyte in asphyxial neonates.Methods To test the concentration of blood serum K~+、Na~+、Cl~-、Ca~(2+) in enzyme linked immunosorbhent assay.In 343 cases,there were 297 cases of slight asphyxial neonates and 46 eases of serious neonates.In control group,there were 41 cases.Results The concentration of blood serum K~+、C~l-、Ca~(2+) in asphyxial neonates were significamly less than control group(all P<0.01) and the concentration after birth 24h~48h were significantly less than within 24h(all P<0.01).The incidence of hyponatremia,hypochloremia and hypocalcemia after birth 24h~48h were significantly hisher than within 24h(all P<0.01),There were no significant differences in the concentration of blood serum K~+、Na~+、Cl~-、Ca~(2+) between the slight asphyxial group and the serious asphyxial group(P>0.05).Conclusions The concentration of blood serum K~+、Na~+、Cl~-、Ca~(2+) in asphyxial neonates gradually reduced after birth 48h and tbe incidence of electrolyte disturbance gradually increased.The change of blood electrolyte should be dynamically routinely monitored.