1.Effect of Kidney nourishing decoction in the treatment of reproduce patients in serum hormone
Chinese Journal of Biochemical Pharmaceutics 2017;37(2):46-48,51
Objective To investigate the effects of Kidney nourishing decoction in the treatment of reproduce patients in serum hormone .Methods 120 cases with reproduce patients from June 2014 to June 2016 in hangzhou traditional chinese medical hospital were selected,and divided into control group and experiment group, 60 cases in each group.The control group was given artificial cycle treatment, the experiment group was treated with Kidney nourishing decoction, two groups were treated for three months.Serum sex hormone and AMH content, clinical effect and pregnancy rate were compared before and after treatment.Results Compared with before treatment, levels of FSH, LH, E2 and FSH/LH in two groups decreased, AMH content increased after treatment,the thickness of endometrium and ovarian antral follicle number increased,symptom scores decreased after treatment (P <0.05);Compared with the control group, levels of FSH, LH, E2 and FSH/LH in the experiment group were lower, AMH content were higher, the thickness of endometrium and ovarian antral follicle number in the experiment group were higher,and the symptom scores were lower (P<0.05).The total effective rate of the study group was 90.00% higher than the total effective rate of the control group 73.33% (P<0.05).There was no significant difference in adverse reaction rate between the two groups, the pregnancy rate in the experiment group 30.00% was higher than the control group 11.67% ( P <0.05 ) .Conclusion Kidney nourishing decoction can reduce the sex hormone and increase the content of AMH , and increase the pregnancy rate in the treatment of reproduce patients.
2.From microdosimetry to nanodosimetry--the link between radiobiology and radiation physics.
Journal of Biomedical Engineering 2014;31(3):703-707
The link between micro- and macro-parameters for radiation interactions that take place in living biological systems is described in this paper. Meanwhile recent progress and development in microdosimetry and nanodosimetry are introduced, including the methods to measure and calculate these micro- or nano-parameters. The relationship between radiobiology and physical quantities in microdosimetry and nanodosimetry was presented. Both the current problems on their applications in radiation protection and radiotherapy and the future development direction are proposed.
Humans
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Physics
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Radiation Protection
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Radiobiology
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Radiometry
3.On the compensation mechanism for urban medical services
Chinese Journal of Hospital Administration 2009;25(5):297-301
Reform on medial service compensation mechanism,as a key point in the heahhcare system reform,runs through the entire reform process.It plays a key role for the establishment and improvement of urban medical care system,medical service system,medical management system and operating system,for its guidance and regulation effects.Such a refonn to build a scientific and perfect compensation model and mechanism will be highly significant for the smooth progress of the new round of healthcare reform and its success in the end.
4.Study and management for issues about patients with lupus nephritis after pregnancy
Chinese Journal of Practical Internal Medicine 2001;0(06):-
Systemic lupus erythematosus(SLE)is an autoimmune disease that affects primarily women,commonly in their reproductive years but does not influence fertility.More recent prospective studies indicate that pregnancy is safe for the majority of mothers if it is planned when SLE is quiescent.In pregnant women with lupus nephritis,the outcome of the fetal and maternal is strongly correlated with lupus activity,kidney function and the presence of aPL at the time of conception.To prevent renal complications,prednisone is given after conception,and reinforcement for a few days before the estimated delivery and for a week after delivery or miscarriage with rapid tapering to maintenance levels may be suggested.Treatment of flares includes corticosteroids,hydroxychloroquine,azothioprine and cyclosporin A.Blood pressure is controlled with methyldopa,labetalol nifedipine or hydralazine.
5.The Test of Xuejiejiawei Granule Acute Toxicity The Largest Dose (MTD) of the Determination
Journal of Zhejiang Chinese Medical University 2006;0(05):-
[Objective]Modify Xuejiejiawei Granule judgment toxic particles to guide its clinical drug safety.[Method]Make different dosages,give the mouse to fill stomach,from the observing mouse's physiological condition to judging the medicine toxic.[Result]36 mice after given the medicine observation period do not have an example to die,after the dissection the internal organs have non-pathological changes.[Conclusion] Looking at Xuejiejiawei Granule from the medicine toxic effect,the Xuejie adding the taste pellet is a safe medicine.
6.Drug induced radiation recall dermatitis
China Oncology 2006;0(12):-
Multiple modality treatment has been adapted for the treatment of various cancers,the outcome has been dramatically improved,but some of unique side effects due to the modalities like chemotherapy combined with radiotherapy have been observed in the clinic. Radiation recall dermatitis(RRD) is one of the side effects. In this paper,the etiology,clinical features,diagnosis,treatment and related factors of the radiation recall dermatitis are discussed.
7.Analysis on the Utilization of Blood Lipid-lowering Drugs in 2 Hospitals of Haikou from 2007 to 2009
China Pharmacy 2007;0(30):-
OBJECTIVE:To evaluate the utilization of blood lipid-lowering drugs in Haikou area.METHODS:The consumption sum,DDDs and DDC of blood lipid-lowering drugs in 2 hospitals of Haikou area from 2007 to 2009 were analyzed retrospectively.RESULTS:The consumption sum of blood lipid-lowering drugs in Haikou area increased year by year,up by 41.25% in 2008 than in 2007 and 28.96% in 2009 than in 2008.Blood lipid-lowering drugs were mainly atorvastatin,pravastatin,fluvastatin,simvastatin,bezafibrate.Atorvastatin took up the first place of the list of consumption sum and DDDs in past 3 years.CONCLUSION:Statins occupy the predominate place among blood lipid-lowering drugs and show potential in the market.
8.Clinical Observtion to 30 Cases of Mild and Moderate Ovarian Hyperstimulation Syndrome Treated with Resvised Wupi Decoction
Journal of Zhejiang Chinese Medical University 2013;(10):1201-1203
[Objective] To observe the clinical effects of resvised wu pi decoction on mild and moderate ovarian hyperstimulation syndrome. [Method]To 30 of such cases ,take resvised wu pi decoction to strengthen spleen and tonify kidney, remove dampness and prevent miscarriage, observe patient chest dis-tress, abdominal distension and liquid intake and output volume of 24 hours etc.;Then estimate the clinical effect,and analyze one typical case.[Result]The marked effective rate was 60.00%, with total effective rate 96.67%. [Conclusion] The clinical application of resvised wu pi decoction treating mild and moderate OHSS by strengthening spleen and tonifying kidney,removing dampness and preventing miscarriage has excellent curative effect.
9.Detection of serum osteopontin in patients with pemphigus vulgaris
Chinese Journal of Dermatology 2015;48(1):53-54
Objective To investigate the role of serum osteopontin in the occurrence of pemphigus vulgaris (PV).Methods Enzyme-linked immunosorbent assay was conducted to determine serum levels of osteopontin in 31 patients with PV and 35 healthy human controls.Statistical analysis was carried out by t test and Spearman rank correlation analysis with the SPSS 17.0 software and Excel.Results Serum levels of osteopontin were significandy higher in patients with PV than in healthy controls (P < 0.01),in patients with mucocutaneous involvement than in those with only cutaneous involvement (P < 0.05),and in patients with complicated infections than in those without (P < 0.01).There was a positive correlation between serum levels of osteopontin and anti-Dsg3 antibody in patients with PV (rs =0.489,P < 0.01).Conclusions Serum levels of osteopontin are increased in patients with PV,especially in those with mucocutaneous involvement,and positively correlated with PV-related antibody titers.
10.The effect of aerobic exercise on serum IL-4 and TNF-alpha of patients with allergic rhinitis.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(23):1321-1323
OBJECTIVE:
To investigate the effect of aerobic exercise on immune factor IL-4, TNF-alpha in patients with allergic rhinitis, which provide a theoretical basis for the treatment of allergic rhinitis.
METHOD:
Thirty-two allergic rhinitis patients were selected and divided into a control group (14 people) and the experimental group (18 people). During the treatment, both groups receive conventional symptomatic treatment. Meanwhile, aerobic exercise therapy is applied to the experimental group for 40 - 60 minutes a day, 3 - 4 days a week. Serum IL-4, TNF-alpha and allergic rhinitis symptoms graded scoring were tested before and after 6 month therapy.
RESULT:
After six months of exercise intervention, the 11-4, and TNF-alpha levels of experimental group were significantly lower than the level of control group. The symptoms score is also significantly decreased in experimental group.
CONCLUSION
Aerobic exercise had good therapeutic effect in patients with allergic rhinitis. The mechanism may be that aerobic exercise can reduce the level of IL-4 and TNF-alpha, which can relieve infiltration and activation of inflammatory cells.
Adolescent
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Adult
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Exercise
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Exercise Therapy
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Female
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Humans
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Interleukin-4
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blood
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Male
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Rhinitis, Allergic
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Rhinitis, Allergic, Perennial
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blood
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therapy
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Tumor Necrosis Factor-alpha
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blood
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Young Adult