ObjectiveTo discuss the relationship between serum homocysteine (Hcy) level and severity of acute coronary syndrome(ACS) through measuring the level of serum Hey in the patients with ACS.Methods95 patients who were diagnosed ACS were divided into two groups:40 cases of unstable angina(UA) and 55 cases of a cute myocardial infarction(AMI).30 individuals were chosen as normal control(NC).In addition,according to the results of coronary angiography,the same 95 patients were further divided into three subgroups which were single-vessel disease( 28cases),double-vessel disease ( 36cases ) and multi-vessel disease ( 31 cases ).Level of serum Hcy was measured in all groups.ResultsSerum Hcy level of ACS patients was significantly higher than NC group( P ＜ 0.01 ).The level of serum Hcy in AMI group was significantly higher than that in UA group( P ＜ 0.05 ).The Hcy level in the multi-vessel disease group,double-vessel disease group and single-vessel disease group were increased in turn,and the difference of pairwise comparison was statistically significant ( P ＜ 0.05 ).ConclusionThe serum Hcy level has rela tionship with the severity of coronary lesions and is directly proportional to the number of coronary artery lesions.The result suggests that the level of serum Hcy maybe play an important role in the prevention,diagnosis,treatment and monitoring of ACS.

Diagnosis, Differential ; Drugs, Chinese Herbal ; therapeutic use ; Humans ; Medicine, Chinese Traditional ; Neoplasms ; diagnosis ; drug therapy ; Phytotherapy ; Quality of Life ; Treatment Outcome

Child, Preschool ; Facial Paralysis ; etiology ; Female ; Hand, Foot and Mouth Disease ; complications ; drug therapy ; Humans

Objective To investigate the effect of intensive nursing intervention on the secondary infection in chemotherapy of elderly patients with lung cancer.Methods 168 cases of elderly lung cancer patients whose neutrophil ≤ 1.0×109/L during chemotherapy were randomly divided into two groups,namely,the intensive care group and the control group,with 84 cases in each group.The control group was given routine nursing of infection prevention,while the intensive care group was given intensified nursing for infection prevention.A contrastive analysis was conducted in terms of the incidence,clinical characteristics and the duration of antibiotic treatment of the two groups of patients with secondary infection.Results The secondary infection rate of the intensive care group was lower than that of the control group during chemotherapy.What's more,the duration of fever and treatment of the intensive care group was shorter than that of the control group,hence the patients were safe during infection period.The difference was statistically significant.Conclusions Strengthening the nursing intervention can reduce the incidence rate of secondary infection in aged patients with lung cancer,increase the tolerance of patients to chemotherapy and ensure the successful completion of the chemotherapy cycle,prolong the life span of the patients with an improved quality of life.

Humans ; Liver Cirrhosis

Anal Canal ; surgery ; Humans ; Postoperative Complications ; Rectal Neoplasms ; surgery

Bladder cancer is the most common malignant tumor in urogenital system. Bladder carcinoma has the biological characteristics of easy recurrence and metastasis. The cancer stem cells theory explained the mechanisms of bladder cancer recurrence and metastasis. Epithelial-mesenchymal transition ( EMT) could promote tumor cells to acquire stem cell characteristics, while the tumor cells with stem cell characteristics have correspondingly high expression of EMT biomarkers. Long noncoding RNA ( lncRNA) promotes tumor cells to acquire and maintain stem cell characteristics through regulating EMT process. CSCs, EMT and lncRNA are closely related to the genesis and development of tumors, and participate in the regulation process of tumor proliferation, invasion, me-tastasis and so on. It will provide new insights in targeting therapy of tumor metastasis and recurrence through illuminating the correla-tion between lncRNA on EMT of bladder cancer stem cells ( BCSCs) This article makes a review on the latest research progress about the mechanism of lncRNA regulating EMT of BCSCs.

OBJECTIVE　To prepare the piroxicam films and study its characteristics of transdermal delivery.METHODS　Different high polymers were employed to prepare piroxicam films.Rat abdomen skin and modified Franz diffusion cells were used in the drug penetration tests and release tests.The percutaneous penetration rate was investigated.RESULTS　The release rate of piroxicam films was 64.31 μg*cm-2*h-1.The in vitro permeation rate was 14.86 μg*cm-2*h-1.The percutaneous penetration rate was 11.94 μg*cm-2*h-1.CONCLUSION　Piroxicam films was developed.

The concept of autoinflammatory diseases and autoimmune diseases is different but similar.With the genetic background and inflammation pathways of many autoimmune diseases elucidated,some kinds of diseases are facing a new partition.The explaination of immunological disease continuum update the concept of some diseases and benefit from the treatment.

Anaerobic ammonia oxidation (Anammox) is one of the important discoveries in the field of environmental microbiology, and it plays an indispensible role in the nitrogen removal from wastewaters and the biogeochemical nitrogen cycle. Through review research progress in anaerobic ammonia oxidation, an Anammox special issue is published so as to find problems, explore applications and outlook developments. The special issue consists of reviews and original papers, mainly involving in the following aspects: i) enrichment of Anaerobic ammonia oxidation bacteria (AnAOB); ii) community analysis of AnAOB; iii) preservation of granular AnAOB sludge; iv) effect of organic matter on Anammox; v) application of Anammox process, etc.
Ammonia ; chemistry ; Bacteria, Anaerobic ; metabolism ; Environmental Microbiology ; Nitrogen ; chemistry ; Nitrogen Cycle ; Oxidation-Reduction ; Sewage ; microbiology ; Waste Disposal, Fluid ; Waste Water ; chemistry