Nine compounds derivated from 2-mercaptobezothiazole were synthesized. Their structure have been identified by MS-, IR-, and UV- spectroscopy. Antimicrobial activities of some compounds have been tested. Hydrazide BT6 and substituted hydrazides BT7, BT8, BT9 were found to have significant inhibitory activity on P. aeruginosa, S. aureus, Asp. niger and F. oxysporum at concentration 50mcg/ml.
Pharmaceutical Preparations

Realtime xCELLigence analysis (RTCA) is a new cell detection technology to continuously monitor, record and analyze a variety of information generated by cell activity. In drug research, it plays an important role in assessing myocardial toxicity and cell biological activity. Here, we first introduce the underlying mechanisms and characteristics of RTCA. Then we review the applications of RTCA in the research of myocardial toxicity and cell biological activity, to provides the fundamental baseline for understanding and exploiting RTCA. With the real-time, unlabeled, non-invasive, high throughput, and high accuracy features, RTCA not only promotes drug research and development, but also has a broad and good application prospect in other fields.
Pharmaceutical Preparations

According to the results of an investigation on 270 households in May 1999 carried out in Tien Son district, Bac Ninh province, 56 (20.79%) purchasing households came to commune health centre, 195 (72.22%) came to private clinic, 8 (2.96%) came to public pharmacy and 11 (4.03%) came to private pharmacy. Quality of the drug, easiness to access, reasonable price, good counseling... are the favorable factors to promote the purchaser's choice
Pharmaceutical Preparations ; Pharmaceutical Services

Sustained release dosage forms belong to new forms with innovative bioavailability, in which drug was released in tailored design. If physicians haven't a firm grasp on nature, composition of dosage form and give incorrect instruction for use, model of release dosage of drug will be changed, and drug is not only less effective but also harmful. Author introduced technical rules of preparing sustained release drugs, sustained release dosage forms and pathways of administration
Pharmaceutical Preparations ; Dosage Forms

to build formula of captopril sustained release matrix tablets with EC and HPMC, survey the affects of formulation components and optimization of formula by using D- Optimal. Subject: captopril, EC, HPMC, lactose, and starch. Method: prepare tablet, assess the quality of captopril sustained release matrix tablets. Conclusions: From the experiment design, captopril sustained release oral tablets with half life of 12h can be prepared, and by optimized method, the proper formula was found. To produce captopril tablets, it's necessary to further study in large scale, to perform test of bio-equivalence and stability of tablet
Captopril ; Tablets ; Pharmaceutical Preparations

The retail price of some domestic produced medicines had the tendency to increase in line with the increase rate of consumption commodities from 2001 to April 2004. Some kinds of medicines had surveyed as follow: antibiotics; vitamines; reliever; antifebrile; anti- inflamatory; digestion drug, and other medicines. The variation of price of those medicines at that time compared with the rate of consumption commodities, the variation of rate of USA and EURO. The price of consumption commodities increased rate of 3.61% in 2002 compared with 2001. the price increased rate of 3.03% compared with 2003 and during 3 months of 2004 the price of consumption commodities increased 5.40% compared with 2003
Pharmaceutical Preparations ; Commerce ;

Labour induced effect of misoprostol in comparing with oxytoxin on the ending 3rd trimestre of pregnancy was studied in 180 subjects at the Central Hospital of Gynecology and Obstetrics from January 1997 to January 2003. In 89.89% of misoprostol applicants and 67.78% of oxytoxine applicant success were reached. Labour induced meantime of misoprostol applicants 6.25  2.07 hours, oxitoxine 4.31  2.29 hours. Vaginal tract delivery in 88.3% of misoprostol applicant group and 70% of oxytoxine. Caesarian section 27.78% in misoprostol group, lower than oxytoxine group 44.44%.
Misoprostol ; Oxytocin ; Pharmaceutical Preparations

Study on 70 patients with chronic inflamagingival at the age of 17-34 and 35-55. These patients have treatment with tooth-ointmently by ultra in the Institute No103, from October 2002 to October 2003. The results showed that: the cause of chronic inflamgingival was tooth-ointmently. In 2 studied groups, each patient have averagely 4 areas having tooth-ointmently, mainly inside of large molar tooth of lower jaw and outside of large molar tooth of upper jaw. The good results have achieved after one week and maintained after 3 months of treatment with tooth-ointmently by ultra combined with guiding dental hygiene. After 6 months, the good results have decreased highly. The patients need to take tooth-ointments again, to be guidlined and practised well dental hygiene
Gingivitis ; Pharmaceutical Preparations ; Tooth

A theoretical study on eight extra channels includes: the Du channel, the Ren channel, the Chong channel, the Dai channel, the Yinwei channel, the Yangwei channel, the Yinqiao channel and Yangqiao channel. They doesn’t look like 12 main channels depend on viscera and there is no relation of internal-external. They tied closely with the extra-fu organs (the brain and uterus). A clinical application often use single point therapy, the application of stimulation at one point of the superficial of the body, the correlative leg-hand therapy to feel the point, the internal-external combining therapy, lower point for upper disease, upper point for lower disease, feeling right-left point, yin-yang co-point. Their application can be used in treatment for several conditions such as lose consciousness due to high fever, stroke, angina pectoris, cardiac arrhythmia, non-palpable pulse, hypertension and nervous depression
Pharmaceutical Preparations ; Therapeutics

Using the full quadratic model in drug dissolution optimization, the authors built up the sustained release of diclofenac tablet formulation with hydrophilic matrix excipient. The sustained excipient releases xanthan gum which has good features such as controlling medical substance regularly, rubbing seed easily, covering tablet easily and compressed force with a little affect to the rate of medical substance release. This formulation can be applied in making up medicines with a wider scale. It is being tested its stability and evaluated its availability to apply in manufacture
Diclofenac, Pharmaceutical Preparations , Tablets