According to the results of an investigation on 270 households in May 1999 carried out in Tien Son district, Bac Ninh province, 56 (20.79%) purchasing households came to commune health centre, 195 (72.22%) came to private clinic, 8 (2.96%) came to public pharmacy and 11 (4.03%) came to private pharmacy. Quality of the drug, easiness to access, reasonable price, good counseling... are the favorable factors to promote the purchaser's choice
Pharmaceutical Preparations ; Pharmaceutical Services

Nine compounds derivated from 2-mercaptobezothiazole were synthesized. Their structure have been identified by MS-, IR-, and UV- spectroscopy. Antimicrobial activities of some compounds have been tested. Hydrazide BT6 and substituted hydrazides BT7, BT8, BT9 were found to have significant inhibitory activity on P. aeruginosa, S. aureus, Asp. niger and F. oxysporum at concentration 50mcg/ml.
Pharmaceutical Preparations

Realtime xCELLigence analysis (RTCA) is a new cell detection technology to continuously monitor, record and analyze a variety of information generated by cell activity. In drug research, it plays an important role in assessing myocardial toxicity and cell biological activity. Here, we first introduce the underlying mechanisms and characteristics of RTCA. Then we review the applications of RTCA in the research of myocardial toxicity and cell biological activity, to provides the fundamental baseline for understanding and exploiting RTCA. With the real-time, unlabeled, non-invasive, high throughput, and high accuracy features, RTCA not only promotes drug research and development, but also has a broad and good application prospect in other fields.
Pharmaceutical Preparations

Study was performed on the preparation of taurine and some taurate salts in the bile of cow/ox from vissan but chery firm. Average weight of bile adder get 80 g for each. From ethamlanin and die thylcarbonate, 2- oxzolidinon was prepared, after the heating with hydrogene sulphide, taurine was obtained with a productivity of 67,15%. The investigation and extraction of taurine in laboratory scale gave a productivity of 64,5%. From taurine, calcium taurate was prepared at a productivity of 90% and magnesium taurate- 83,5%
Taurine ; Salts ; Pharmaceutical Preparations

From androst- 4,9(11)-dien-3,17-dion the synthesis of ethynylsteroid 17 alpha-pregn-11beta, 17-beta-diol-4-en-3-on20-yn was performed with a productivity of 68%. The 17 alpha-ethynylzition gave a productivity of 90%. The by product is 4% of 17 beta- ethynylization product. The product was identified by melting point, IR spectrum, proton magnetic resonance spectrum and mass spectrum
Pharmaceutical Preparations ; Pharmacology ; Androstenedione

The chemical composition of Rhizoma Polygonati (RP) after processing was investigated. The result: All 4 process methods also procedure products no causing itch, black, sweet, soft, plastic. The chemical composition of unrefined Rhizoma Polygonati contained Alcaloid, Flavonoid, Sterol, Sugar, Iridoid glycosid, Amino acid and Fat. On the thin layer chromatograph, total alcaloid of Rhizoma Polygonati processed by a way had 4 spots, total flanoid had 4 spots, 1 spots of them cleare blue. The total sugar content of Rhizoma Polygonati processed by a way is 33,4% and of unrefined Rhizoma Polygonati is 12,63%. Both unrefined RP and processed RP also have 17 acid amin, among 7 essential acid amin for the body. The content of this acid amin of processed sample is usually higher than of unrefined sample
Chemistry ; Pharmacology ; Pharmaceutical Preparations

Compounding pellet chlorpheniramin TDKT and builing its formulary from pellet were studied. The result: the optimal formule of memberance prolonging release of chlorpheniramin from pellet was selected. This memberance could quicktly release a part of primary subtance in order to immediately solve alergic symptoms. The rest release constantly prolong in 8 hours
Chlorpheniramine ; Pharmaceutical Preparations ; Membranes

From 2000-2004, the authors examined medicament were imported and delivered in Lao Cai province to investigate quality of them. Results showed that: the rate of bad quality medicament was 4.9%, among which the rate of injection drugs was higher than tablet drugs. The domestic medicament had a bad quality was higher than imported medicament (5.3% vs. 3.2%, respectively). The bad quality rates of vitamins and tonic drugs were the highest (6.7%), antibiotics 2.6%. This rate in the mountain and rural areas was higher than that in the city.
Pharmaceutical Preparations ; Epidemiology

Study on 41 pharmaceutical companies in Hanoi city from March 1999 to February 2000. The results: there was an average of 46 pharmaceutical companies of sixteen countries bought the biding documents and about 43% of those companies submitted the bid documents. At each International Competitive Bids, the average of prices of pharmaceutical drugs were correlative with that announced by UNICEF, however, there was still a case of the mean prices of pharmaceutical drugs were higher than that announced by UNICEF. The prices of pharmaceutical drugs were considered lowest, lower than the average of prices of similar products, which were imported into the Vietnam market and announced by UNICEF
Pharmacy ; Pharmaceutical Preparations

Antimalarial drug samples were collected from different parts of the country for quality investigation in 2004. A total of 129 samples of different batches were collected at three rounds and cross-checked at local, central level and abroad. At the round one, three out of 49 collected samples were found substandard. One of 40 samples of the second round was determined counterfeit (2.5%). The re-analysis of 51 samples at NIDQC revealed two from the first round were substandard and one from the second round was counterfeit
Malaria ; Therapeutics ; Pharmaceutical Preparations