Objective: To investigate the antibacterial activity and phytochemical screening of the hexane, chloroform, ethyl acetate, ethanol and aqueous stem extract of Dalbergia coromandeliana (D.coromandeliana ). Methods: The antibacterial activity of stem extracts of D. coromandeliana were evaluated by agar well diffusion method against four selected bacterial species. Results:The presence of alkaloids, saponins, coumarins, tannins, steroids, flavonoids, quinones, proteins and carbohydrates in the different stem extracts was established. Conclusions: The results in the present study suggest that D. coromandeliana stems can be used in treating diseases caused by the tested organisms.