[Objective]To evaluate the surgical results of posterior hemivertebra resection in the treatment of congenital kyphoscoliosis caused by hemivertebra.[Method]From May 2000 to November 2005,14 cases with hemivertebra treated with one stage posterior hemivertebra resection were reviewed,which included males and females.All the cases underwent one stage posterior hemivertebra resection,fusion and correction with instrumentation.The mean age at time of surgery was 7.4 years old.Location of the hemivertebra included 7 cases at thoracic spine and 7 cases at lumbar spine.[Result]The mean operation time was 4.7 hours,the mean blood loss and blood transfusion during operation was 500 ml and 560 ml respectively.The fusion level was 2 to 8 segments,average 3.5 segments.Scoliosis was corrected from 46.2? to 17.3?with a correction rate of 62.6%.Kyphosis was corrected from 48.3? to 16.2? with a correction rate of 68.7%.At the final follow-up,the coronal Cobb's angle was 21.7? with a 4.4? loss of correction;the sagittal Cobb's angle was 18.7 with a 2.50 loss.Peri-operative complication included two of implant malposion,delayed wound healing.No reoperation due to the progressive deformititie was need.[Conclusion]One stage posterior hemivertebra resection has a good capability of correcting congenital kyphoscoliosis caused by a singe hemivertebra.It can save operation time and is less invasive compared to combined approach,and is indicated to thoracic and lumbar hemi-vertebra with fewer complications.

Objective:To investigate the curative effect and safety of Stoppa approach combined with iliac fossa approach in the treatment of the patients with coxafossa anterior column or coxafossa dual column bone fracture, and to provide a scientific evidence for its application in the treatment of the patients with coxafossa anterior column or coxafossa dual column bone fracture.Methods:Sixty-three patients with coxafossa anterior column or coxafossa dual column bone fracture were selected;among them 32 cases were treated with stoppa approach combined iliac fossa approach(Stoppa group),and 31 patients were treated with ilioinguinal approach(control group).The intraoperative blood loss volume,the operaton time,the reset quality of fracture and hip joint function after operation of the patients in two groups were evaluated.Results:The intraoperative blood loss volume of the patients in Stoppa group was lower than that in control group, and the difference was statistically significant (P<0.05).The operation time of the patients in Stoppa group was shorter than that in control group, and the difference was statistically significant (P<0.05).The reset quality of fracture of the patients in stoppa group was higher than that in control group, and the difference was statistically significant (P<0.05).The hip joint function of the patients in Stoppa group was higher than that in control group, and the difference was statistically significant (P<0.05).Conclusion:Stoppa approach combined with iliac fossa approach is an effective method in the treatment of the patients with coxafossa anterior column or coxafossa dual column bone fracture with sufficient exposure and tiny tissue damage.Stoppa approach combined with iliac fossa approach in the treatment of the patients with coxafossa anterior column or coxafossa dual column bone fracture has the advantages of shorter operative time,less blood loss, higher rate of anatomic reduction,and good joint function.

AIM: To determine the effect of promoting cellular cholesterol efflux on the apoptosis of foam cells derived from monocytes. METHODS: RAW264.7 cells were incubated with 50 mg/L ox-LDL as a foam cell mode. The apoptosis rate of RAW264.7 cells was assayed by flow cytometry. Cellular lipid droplet was assayed by oil red staining. The rate of cellular cholesterol efflux was assayed with [~3H] label cholesterol, and the content of cellular cholesterol were assayed by high performance liquid chromatography. RESULTS: After incubation with 50 mg/L ox-LDL for 48 h, the content of cellular cholesterol ester increased from (6.8?3.6) mg/g to (101.7?4.5) mg/g (P