1.Clinical Observation on Scapulohumeral Periarthritis Treated by Tuina and SSP Meridian Therapeutic Apparatus
Journal of Acupuncture and Tuina Science 2004;2(3):37-39
Purpose: To observe the therapeutic effect of Tuina plus meridian therapeutic apparatus on scapulohumeral periarthritis. Methods: Thirty-five cases of scapulohumeral periarthritis were treated by Tuina plus Japan-made SSP meridian therapeutic apparatus in the observation group, and 30 cases were treated by single meridian therapeutic apparatus in the control group. Results: Certain therapeutic effects had been achieved in the treatment of scapulohumeral periarthritis in the two groups. But, there is an obvious difference (P<0.01) in the curative rate between the observation group and control group,and the curative rated was remarkably higher in the observation group than in the control group.Conclusion: Tuina plus meridian therapeutic apparatus is an effective method for scapulohumeral periarthritis.
2.Experimental Study on Anti-inflammatory, Diuretic Effect and Acute Toxicity of Herb of Lanceolate Sedge
Chaoyun ZHANG ; Xianzhang HUANG ; Pengfei HAO
World Science and Technology-Modernization of Traditional Chinese Medicine 2014;(5):1201-1204
This study was aimed to investigate the anti-inflammatory, diuretic effect and acute toxicity of Herb of Lanceolate Sedge. The mice were randomly divided into 5 groups, which were the physiological saline group, aspirin group (0.05 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of water extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medication was given to mice once a day for 3 days. Auricular swelling induced by dimethyl benzene was used in the model establishment to calculate the swollen ear degree and the swollen inhibiting rate. And rats were randomly divided into 5 groups, which were the physiological saline group, aspirin group (0.05 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of wa-ter extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medi-cation was given to rats once a day for 5 days. Carrageenan induced paw edema was used in the model establishment to calculate the paw swollen rate. And rats were randomly divided into 5 groups, which were the physiological saline group, Furosemide tablets group (0.01 g·kg-1), high dose (HD), middle dose (MD) and low dose (LD) of water extract of Herb of Lanceolate Sedge (10, 5, 2.5 g crude drug per kg) group. Intragastric administration of medication was giv-en to rats once a day for 5 days. Water-loaded was used in the model establishment to calculate the 5-hour urine amount. The maximum tolerance dose (MTD) was used in the determination of the acute toxicity. The results showed that the three groups of HD, MD and LD of water extract of Herb of Lanceolate Sedge had obvious inhibiting effects on the swollen ear degree and the swollen inhibiting rate among mice, and the paw swollen rate of rats. It had signif-icant increasing effect on the 5-hour urine amount. The MTD of intragastric administration of water extract of Herb of Lanceolate Sedge was 640 g crude drug per kg for mice. It was concluded that Herb of Lanceolate Sedge dis-played obvious effects on anti-inflammatory and dieresis with low acute toxicity.
3.Optimization on Microwave Extraction Crafts for Polysaccharide from Radix Platycodonis Based on Orthogonal Test
Chaoyun ZHANG ; Pengfei HAO ; Xianzhang HUANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2013;(7):1644-1648
This study was aimed to select the best microwave extraction craft conditions of polysaccharide from Radix platycodonis. The composite scores of polysaccharide content and yield rate were used as evaluation indexes. By ex-amining the impact of microwave power, microwave time, extraction times and solid-liquid ratio on crafts, the best craft conditions were optimized by orthogonal test. The orthogonal test showed that when the microwave power was 1800 W, microwave time was 8 min, extraction times were 3, solid-liquid ratio was 1:15, the composite scores were the highest and the extraction craft conditions were the best. It was concluded that the crafts are efficient and stable. It had laid a foundation for the further study on polysaccharide from R adix p latyc odonis .
4.Clinical Efficacy of Xuebijing Injection for Severe Acute Pancreatitis
Kai LENG ; Zhengtao HUANG ; Pengfei ZENG
China Pharmacy 2007;0(27):-
OBJECTIVE:To observe the clinical efficacy of Xuebijing injection in the treatment of severe acute pancreatitis(SAP).METHODS:65 patients with severe acute pancreatitis were enrolled:30 patients in the control group were randomly as-signed to receive standard combined therapy of west medicines,and 35 in the treatment group to receive Xuebijing injection 100 mL qd by iv gtt plus the combined therapy as in the control group.The course of treatment in both groups was 7 days.RESUL-TS:The total efficiency in the treatment group was 94.3% and that in the control group was 83.4%,showing significant differences between the two groups(P
5.Integrin ?2 and ?3 expression and its clinical value in bladder transitional cell carcinoma
Fanghu SUN ; Pengfei SHEN ; Jiangbo HUANG
Chinese Journal of Urology 2001;0(11):-
50%).RT-PCR results were classified as positive and negative according to the presence or absence of corresponding electrophoretic bands. Results Immunohistochemically,integrin ?2 and ?3 subunits were all expressed strongly in 12 cases of normal bladder tissues (100%).In 53 cases of BTCC tissues,?2 was strongly positive in 10 cases (19%),positive in 22(42%),negative in 21(40%);?3 was strongly positive in 16 (30%),positive in 24 (45%),negative in 13(25%).The expressions of ?2 and ?3 were significantly different between normal and BTCC tissues ( P 0.05).RT-PCR results showed that ?3 expression was positive in all normal tissues (100%) and in 36 (68%) out of the 53 cases of BTCC tissues;the difference was significant ( P 0.05),but ?3 mRNA positive expression was significantly related to clinical stages [T is ~T 1:83%(19/23),T 2~T 4:57%(17/30); P
6.A study on ego identity and mental health of students in athletes and their relationship
Yuanbing GUO ; Chaoyun HUANG ; Pengfei SUN
Chinese Journal of Behavioral Medicine and Brain Science 2008;17(11):1031-1033
Objective To study the ego identity,mental health and their relationship among students in athletes.Methods 110 students in athletes and 122 athletes in students were measured with identity status scale and athletes' symptom checklist.Results ①Students in athletes have higher "present serf-commitment" (5.09±1.07)and lower "crisis in the past"(2.19±1.12)than athletes in students.The two demonstrate the obvious difference on the distribution of identity status.The percentage of students in athletes obtaining A is lower than that of athletes in students ,while the percentage of students in athletes obtaining D and MD is higher. ②Comparing with the norm,students in athletes have higher level on the factors of sematizafion (1.98±0.42),compulsion (2.21±0.51),interpersonal sensitivity(2.09±0.53),depression (1.85±0.53),anxiety ( 2.47 ~0.58 ),paranoid (1.98±0.21),psychoticism (1.79±0.22) and total average marks (2.00±0.34),lower level on the factors of hostility (1.43±0.48)and cognitive(1.64±0.31). ③Three domains of ego identity exit obvious negative correlation with the sores of psychological symptoms.ANOVA confined that the more advanced ego identity is,the better mental health is.Conclusion Ego identity and mental health of students in athletes have their own features,and ego i-dentity will influence mental health.
7.The clinical, endoscopic and pathologic features of Crohn's disease in the differentiation from intestinal tuberculosis
Li CHENG ; Meifang HUANG ; Pengfei MEI ; Wenhui BO ; Changsheng DENG
Chinese Journal of Internal Medicine 2013;52(11):940-944
Objective To investigate the clinical,endoscopic and pathologic features in the differential diagnosis between Crohn' s disease (CD) and intestinal tuberculosis (ITB).Methods The complete clinical data of 107 patients with CD and 69 patients with ITB in our hospital from January 2011 to January 2012 were retrospectively analyzed.The diagnostic value of the clinical and endoscopic scoring system was evaluated.Results CD occurred mainly in male.The salient features of CD included long duration of disease high incidence of colectomy.Comparing with patients with ITB,patients with CD have more cases of diarrhea,hematochezia,abdominal mass,intestinal obstruction,intestinal hemorrhage,perianal lesions,and extraintestinal manifestations (all P < 0.05).It's more frequent to have positive results of anti-Saccharomyces cerevisiae antibody (ASCA),perinuclear antineutrophil cytoplasmic antibody (pANCA) and fecal occult blood in CD patients,as well as low albumin,high C-reactive protein (CRP),elevated platelet count and hematocrit (P < 0.05 or P < 0.01).The salient features of ITB included low fever,night sweats,active parenteral tuberculosis,increased erythrocyte sedimentation rate (ESR),chest X-ray abnormalities,the positive PPD (purified protein derivatives tuberculin) and T-SPOT (P < 0.05 or P <0.01).Based on the imaging,CD often involved the small intestine,such as the intestinal stricture and abdominal abscess (P < 0.05),while mesenteric lymphadenopathy was more common in ITB (P < 0.05).The endoscopic examination showed that some patterns of disease involvement such as fissure-shape ulcer [41.12% (44/107) vs 5.80% (4/69)],cobblestone sign [15.89% (17/107) vs 4.35% (3/69)],lesions over four segment [24.30% (26/107) vs 7.25% (5/69)],rectum involvement [17.76% (19/107) vs 5.80% (4/69)],ileocecal valve stenosis [21.50% (23/107) vs 8.70% (6/69)] and mucosal bridge [5.61% (6/107) vs 0(0/69)] were more frequent in CD patients than those in ITB patients(P < 0.01 or P <0.05).However circular ulcers[37.68% (26/69) vs 9.35% (10/107)],rat-bite-like ulcers[24.64% (17/69) vs 12.15% (13/107)],persistent open ileocecal valves [39.13% (27/69) vs 19.63% (21/107)],tuberous and polypoid lesions [36.23% (25/69) vs 20.56% (22/107),37.68% (26/69) vs 22.43% (24/107)] were more common in ITB (P < 0.01 or P < 0.05).In terms of pathological findings,certain characteristic features such as transmural inflammation [5.61% (6/107) vs 0 (0/69)],fissure-liked ulcers [14.02% (15/107) vs 4.35% (3/69)],non-caseous granulomas [5.61% (6/107) vs 0(0/69)],lymphoid hyperplasia [16.82% (18/107) vs 5.80% (4/69)] and crypt abscess [9.35% (10/107) vs 1.45% (1/69)] were more common in CD than those in ITB(P < 0.05).According to the clinical and endoscopic scoring system,the positive diagnostic rate of CD was 50.47 % (54/107)and of ITB was 66.67 % (46/69) (P < 0.05).Conclusions The differential diagnosis between CD and ITB should be considered carefully based on clinical,endoscopic,pathological characteristics.The clinical and endoscopic scoring system may contribute to distinguish CD and ITB.
8.Ultrasonic Extraction Process Research and Mathematic Simulation of Tyrosol in Rhodiolae Crenulatae Radix et Rhizoma
Yufang HUANG ; Xiaofeng SHI ; Juli YUAN ; Pengfei XIA
Chinese Journal of Information on Traditional Chinese Medicine 2015;22(11):89-91
Objective To study the ultrasonic extraction technology of tyrosol in Rhodiolae Crenulatae Radix et Rhizoma;To mathematically simulate the extraction process.Methods The content of tyrosol was set as index;HPLC was used;the ultrasonic extraction process of tyrosol in Rhodiolae Crenulatae Radix et Rhizoma was optimized by an orhogonal experiment and mathematic simulation.Results The optimum ultrasonic extraction conditions were as follows:80%ethanol was used as extraction solvent, the ratio of material to liquid was 1:35 (g:mL), with the extraction time of 30 min and ultrasonic power of 240 W. In these conditions, the extracting rate of tyrosol was 0.150 1%. Compared with the heating reflux method, the extraction time should be shortened by 66.7% and the extracting rate should be increased by 12%.Conclusion The extraction method is simple and the extraction rate of effective components is high. Mathematical simulation values based on ultrasonic extraction are consistent with experiment values.
9.Clinical study of the influence of continuous hemofiltration on gastrointestinal dysfunction of the patients with intra-abdominal hypertension
Xin XU ; Man HUANG ; Pengfei WANG ; Qiuping XU
Chinese Journal of Emergency Medicine 2014;23(10):1138-1142
Objective To investigate the effects of continuous hemofihration on gastrointestinal dysfunction for treating patients with intra-abdominal hypertension.Methods A total of 37 patients were divided into two groups randomly (random number),namely control group (n =17) and continuous blood filtration (CBF) group (n =20).The patients of control group were treated with routine treatment,and the patients of CBF group were given CBF for 72 hours in addition to the routine treatment.The intra-abdominal pressure (IAP),gastrointestinal (GI) symptoms,and SOFA score were documented at 0 hour,24 hours,72 hours and 7 days after treatment.Results The MAP of patients in the CBF group was not significantly changed (P =0.218),while the IAP was decreased significantly (P =0.001) and the abdominal perfusion pressure (APP) increased significantly after CBF (P =0.036).Compared with the control group,there were more than 2 GI symptoms markedly relieved after CBF for 24 hours (P =0.049).The SOFA score of CBF group decreased significantly (P =0.037).There were no differences in 28-day and 60-day mortality between two groups.Conclusions The CBF can decrease IAP,increase APP,improve splanchnic blood circulation,and ameliorate gastrointestinal dysfunction.But CBF does not reduce the mortality in comparison with routine treatment.
10.Expression of microRNA-210 in gastric cancer and its relationship with clinicopathological factors and prognosis
Pengfei YU ; Yian DU ; Litao YANG ; Gaiguo DAI ; Ling HUANG
China Oncology 2017;27(3):197-200
Background and purpose: miR-210 was closely related to the occurrence and development of gastric cancer, but its mechanism and clinical significance were still not clear. The purpose of this study was to explore the expression of miR-210 in gastric cancer tissues and its clinical significance. Methods: The expression of miR-210 was detected in gastric cancer tissues and the corresponding adjacent tissues. The relationship between the expression of miR-210 and clinical pathological factors and prognosis was analyzed. Results: Real-time fluorescent quantitative polymerase chain reaction (RTFQ-PCR) showed that the expression of miR-210 in gastric cancer was higher than that in adjacent tissues, and there was a significant difference between the two groups (P<0.05). The expression of miR-210 was closely related to tumor size, lymph node metastasis and TNM stage, but was not related to age, gender, tumor dif-ferentiation and depth of invasion. The 5-year survival rate of patients with low miR-210 expression was 48.2%, where-as the 5-year survival rate of patients with high miR-210 expression was 30.4% (χ2=4.216, P=0.040). Conclusion: The expression of miR-210 in gastric cancer was higher than that in adjacent tissues, and maybe related to the development and prognosis of gastric cancer. miR-210 is expected to be a new diagnostic marker and therapeutic target for gastric cancer.