Objective:To evaluate the effectiveness of procedure for prolapse and hemorrhoids(PPH) in the treatment of severe hemorrhoids.Methods:The experiment group(also called PPH group) consisting of 11 cases was subjected to PPH,the controlled group with 12 cases to Saresola-Klose method.Results:This study showed that the operating time and hospital stay after operation in PPH group were shorter than those in control group;less pain, less complication after operation and faster recovery were found in PPH group.Conclusion:PPH has such advantages as short operative time,less postoperative pain,fast recovery,less complications,etc.But its long-term curative effect is to be observed further.

20?g/L)prior to IPA embolization, and returned to normal after embolization. Conclusion Tumors located posteriorly and superticially in the liver may recruit blood supply though IPA collaterals. Phrenospasm should be cautious during IPA embolization.

Objective The localization of AQP4 was studied in the brain,especially,in the periventricular organs,such as ependyma,choroid plexues,area postrema(AP) and neurohypophysis,and telencephalon as well as two kinds of endocrine gland:pineal gland and adenohypophysis,so as to provide morphological basis for water transport and balance,the secretion and regulation mechanisms of endocrine gland in the brain. Methods Immunohistochemical staining techniques(LAB-SA,BCIP/NBT) were used. Results AQP4 was most abundantly expressed in the tissues directly contacting with CSF,including the cerebral pia mater,ependyma lining of ventricules and the aqueductal system and choroid plexues.Heavy express of AQP4 was also found in the perivascular glial processes of the brain tissue.In addition,AQP4 was also distributed to the pyramidal cell layer of hippocampus,granular cell layer and polymorphic cell layer of dentate gyrus,adenohypophysis(intermedius included) and pineal gland cells as well as the periventricular organs such as area postrema(AP) and neurohypophysis.Conclusion The localization of AQP4 indicates that AQP4 is involved in not only the transport and balance of water,electrolyte metabolism and the regulation of secretion of the endocrine gland,but also in the neuroendocrine activity of the hypothalamus.

Objective To explore the curative effect of ursodeoxycholic acid in treatment of intrahepatic cholestasis of pregnancy (ICP) and the effect on total bile acid (TBA) in post partum fetal umbilical venous blood .Methods 30 patients with intrahepatic cholestasis of pregnancy who were admitted into the Hospital Affiliated to Sichuan Medical University during January 2014 to December 2014 were selected as the research objects and randomly divided into observation group and control group ,15 cases in each group.The observation group were given ursodeoxycholic acid tablets while control group were injected with ademetionine butanedisulfonate .The curative effect of two kinds of drugs in treatment of intrahepatic cholestasis of pregnancy was observed and the effect on total bile acid in post partum fetal umbilical venous blood was analyzed .ResuIts After treatment , the TBA and ALT of observation group were significantly lower than those pre-treatment and those of control group (P<0.05).There were no significant differences of TBIL and ALP between two groups and within groups.TBA and TBIL in post partum fetal umbilical venous blood of observation group were significantly lower than those of control group (P<0.05).There was no significant difference of ALT level between two groups .There were two cases of abnormal perinatal outcomes in observation group while seven cases in control group (χ2 =3.97, P<0.05).ConcIusion Ursodeoxycholic acid could effectively reduce the total bile acid levels in maternal and fetal umbilical vein blood, reduce the mortality rate of the fetal and improve the perinatal outcomes , with high security.

In recent years,combined therapy based on radical resection has promoted the prognosis of gastric cancer,but the rate rate of post-surgery recurrence is still high,which is the main cause of death.It helps us take out better treatment for gastric cancer to analyze correlation factors of gastric cancer recurrence after radical resection.It is needed to reviewed the literatures about correlation factors analysis of gastric cancer recurrence after radical resection in recent years.

Lymph node mapping, a hotspot in oncology and surgery in recent years, has been successful-ly used in the discovery and resection of the metastatic lymph nodes in patients with melanoma and breast cancer. For the complex of lymphatic drainage and the defect of tracers, lymph nodes mapping is still under investigation. As a new type of nano-materials, the quantum dots are used widely, the tumor lymph node mapping.

Objective To study the differential expression of hypothalamus proteinum in PMS Liver-qi invasion mouse,in order to find the evidence on pathogenesis in protein level of PMS Liver-qi invasion.Methods The spectrum of a graph on hypothalamus protein of PMS liver-qi invasion symptom was analysed by two-dimensional gel electrophoresis,protein was identified by matrix-assisted laser desorption ionization time of flight mass spectrometry(MALDI-TOF-MS).Results Comparing model group with normal control group in hippocampus were as follows: Ubiquitin carboxy-terminal hydrolase L1,Albumin 1,Aldolase 3 were down-regulated;however M2 pyruvate kinase,ubiquinol-cytochrome creductase core protein I,Calbindin 2 were up-regulated,These protein were related to the function of ubiquitin iter、intermediary metabolism enzyme、compensation.Conclusion PMS Liver-qi invasion was related to the proteinum function of ubiquitin iter、intermediary metabolism enzyme、compensation,this results hint that this six protein were tight related with central pathogenesis of PMS liver-qi reversed symptom.

Based on the superior optical properties and the advantage of surface-modifiable capacity,the novel fluorescent nanoparticle quantum dots can conjugate with many kinds of biomolecules or chemical materials to form target quantum dots,which play an important role in biomedicine.The target ability this probe possesses offers a more accurate tumor localization,and minimizes the side effect to normal cells while strengthens the curative effect.At present,the probe makes a great progress in many areas,such as cell and molecule recognition,imaging in vivo,biosensing and diseases treating.

The establishment of animal model is fundamental to the experimental studies. It involves the selection of animals and cell lines, the determination of the number of cells and the option of the ways of transplant. Only when each production step is operated by following the occurrence and the development mechanism of the gastric cancer, can we simulate the process of growth of the gastric cancer in human body.Due to their congenital immune deficiency, the nude mice serve a better choice for the establishment of gastric cancer animal model. Beyond that, the cell lines selection and transplant way option also play important roles.

Based on clues from the China CNKI database, 52 articles on Y in-Chen-Hao (YCH) decoction in the treatment of jaundice were screened. All modified YCH decoctions were taken. The ExcellPivotTable report and SPSS 19.0 factor analysis were used in the study of compatibility rules of YCH decoctions in the treatment of jaun-dice. The results showed that the prescription was mainly composed of heat-clearing drugs, water-dampness remov-ing drugs, drastic purgative drugs, which were combined with blood-activation and stasis-removing, qi-regulating drugs.