1.Establishing a harmonious doctor-patient relationship based on common values
Journal of Medical Postgraduates 2014;(4):405-407
Doctor-patient relationship is a special relationship between people in special circumstances during a special peri -od, which is directly related to the harmony and stability of society as well as people's quality of life.Values are the fundamental views of people, including the understanding of the nature , composition and standards of values .Doctors and patients are consistent in goals , interests and ideals , having the same objectives to overcome diseases , promote health , and prolong lives .They are essentially unified in values.However, there are some inharmonious phenomena in the relationship between doctors and patients .Efforts should be made to improve the present doctor-patient relationship by the whole society besides doctors and patients , aiming to establish a harmonious doctor-patient relationship of mutual respect , mutual trust , mutual tolerance and mutual cooperation on the basis of common values .
2.The process management about the introduction of new-type medical materials
China Medical Equipment 2014;(4):80-80,81
Objective:To explore the normative procedures for the hospital in introducing the new- into the hospital.Methods: To fill in the application form about the introduction of new-type medical materials into the hospital and to demonstrate them according to the procedures. The evaluation of management effect in normalizing the introduction procedures.Results: Standardize the introduction of new- type medical material flow, a long-term mechanism to establish open and transparent management, perfect the procurement model of hospital. Conclusion: Normalizing the introduction process of new-type medical materials, can make the hospital technological innovation and competitiveness.
3.The Exploitation of Infection Surveillance Information Platform in Hospital Based on B/S Structure
Peng ZHOU ; Dongsheng ZHAO ; Li HAN
Journal of Medical Informatics 2009;30(7):20-22
In order to collect infection surveillance data from hospital to unfold scientific research, infection surveillance information platform based on B/S structure is designed adapting with the object - based technology. The general structures, the possibility of tech-nology realization, function installation and major process of finishing a mission are explained in detail in the paper. Using this platform could not only realize the data sharing between researchers and clinicians but also promote the prevention and control of infection in hospital.
4.Modified minimally invasive total hip arthroplasty through a lateral approach in 43 cases
Yi YANG ; Peng ZHENG ; Jixiong HAN
Chinese Journal of Tissue Engineering Research 2007;0(09):-
From March 2004 to March 2005, 43 patients (49 hips) admitted to Department of Orthopedic Surgery, Fushun Central Hospital for minimally invasive total hip arthroplasty (THA) were selected, including 22 male and 21 female aged 22-79 years. All patients underwent THA with cementless prosthesis. The preoperative Harris scores were (46.2?5.3). For comparison, 35 patients (43 hips) were selected undergoing standard THA at the same period, including 22 male and 13 female, aged 31-78 years; 16 patients underwent THA with mixed prosthesis (cementless prosthesis for acetabulum; cemented prosthesis for the femur), and the others with cementless prosthesis. Their preoperative Harris scores were (43.4?4.6). The perioperative bleeding, operation time, incision length, postoperative functional recovery, and prosthetic position were compared. The THA was succeeded in all patients, and all subjects were followed up for 13.1 months averagely. The perioperative bleeding, drainage, blood transfusion and incision length in minimally invasive THA group were significantly less than standard group (P
5.Related factor analysis on sore throat and pharyngeal xeransis during thyroid surgery
Ting PENG ; Ailin LUO ; Dongji HAN
The Journal of Clinical Anesthesiology 2017;33(6):576-578
Objective To explore the related factors on sore throat and pharyngeal xeransis during thyroid surgery.Methods Twenty-nine female patients, aged 24-67 years, BMI 18-30 kg/m2, falling into ASA physical status Ⅰ or Ⅱ, were scheduled for thyroid surgery.After anesthesia induction and tracheal intubation, the endotracheal intracuff was inflated to 20 mm Hg.Intracuff pressure was monitored every 5 minutes by a pressure transducer.At the time of 24 hours after tracheal intubation, the patients were asked about their throat complaints such as sore throat and pharyngeal xeransis.Results Endotracheal intracuff pressure during thyroid surgery was in a discrete distribution.Multiple linear regression model analysis found that age, BMI, anesthesia time and intracuff pressure had no obvious effects on sore throat.Decision tree model analysis found that patients undergoing thyroid surgery had higher probability of pharyngeal xeransis grade Ⅳ, when the average intracuff pressure was higher than 29 mm Hg.Conclusion Excessive endotracheal intracuff pressure during thyroid surgery due to operation causes pharyngeal xeransis.
6.Study on conditions and influencing factors of physical activity in patients with type 2 diabetes mellitus
Li PENG ; Pan HAN ; Zonghui WU
Chongqing Medicine 2017;46(19):2624-2627,2630
Objective To investigate physical activity in patients with type 2 diabetes mellitus and to analyze its influencing factors,in order to provide references for the prevention and control of disease.Methods A total of 469 cases of patients with type 2 diabetes mellitus were enrolled in this study.The basic information,such as gender,age and so on,and situation of physical activity,including work,housework,transportation and entertainment,were surveyed via questionnaire.Results The total amount of physical activity of patients with type 2 diabetes mellitus in this survey was (1 581.59±743.65)MET-min per week,were mainly contributed from entertainment and housework which was (940.83 ± 547.06) and (407.20 ± 226.63)MET-min per week respectively.The amount of physical activity of patients in different age,occupation,duration of illness and BMI,and patients with or without other chronic diseases were significantly different (P<0.05).Under 45 years old,being on-the-job,with other chronic disease were risk factors for lack of physical activity in patients with type 2 diabetes mellitus (P<0.05),while aged 45-<60 years old,light or normal weight was the protection factors of sufficient physical activity in patients with type 2 diabetes mellitus (P<0.05).Condusion The overall physical activity of patients with type 2 diabetes mellitus is on the medium level,and its main types are entertainment and housework.Patients under 45 years old,being on-the-job,with other chronic diseases have higher risk of lacking physical activity.
7.Experience in treatment of Raynaud's syndrome by chemical sympathectomy:97 cases
Jintao HAN ; Jun ZHAO ; Yongguang PENG
Journal of Peking University(Health Sciences) 2004;0(03):-
Objective:To summarize the curative effect in treatment of Raynaud's syndrome with chemical thoracic sympathectomy(CTS) guided by X-ray since 2001.Methods: From March 2001 to August 2007,97 patients with Raynaud's syndrome(186 limbs) were treated by CTS.Guided by X-ray,a needle was punctured through the back skin to the second thoracic sympathetic ganglion beside the thoracic vertebrae and 2 mL of 5%(v/v) phenol was injected.Results: The first CTS treatment produced a good effect on 146 limbs with an effective rate of 78.5%(146/186).The same treatment was performed on the limbs with no effect 1-2 days after the first treatment and produced good effect on 13 limbs with an effective rate of 32.5%(13/40).The total effective rate of the patients who were hospitalized for the first time was 85.5%(159/186).Of the 97 patients,78 patients(80.4%) were followed up for 47 months on an average with an effective rate of 69.5%.And the rate of complications was 11.4% for pheumothorax,and 3.9% for hydrothorax.Hyperalgesia on axillary region and anterior chest wall;Horner syndrome and sinus bradycardia were rare.Conclusion: CTS is minimally invasive and effective in treatment of Raynaud's syndrome.
8.Advances of Abdominal Multivisceral Transplantation
cheng-hong, PENG ; bao-san, HAN
Journal of Shanghai Jiaotong University(Medical Science) 2006;0(06):-
Abdominal multivisceral transplantation is a new and proved effective therapeutic methods for two or more terminal abdominal organs. Upper abdominal exenteration(resection of the liver,stomach,spleen,pancreaticoduodenal complex,and part of the colon) for the treatment of otherwise unresectable tumors is one of the more radical operations in oncology.Some new surgical methods such as liver-intestinal,liver-kidney,pancreas-kidney and multivisceral cluster transplantation have emerged recently.These new advance surgical approache improve the curative effect of abdominal organ transplantation.
9.Distribution and Drug Resistance of Pathogens by Sputum Culture in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease in Our Hospital
Li MA ; Xiaonian HAN ; Lirong PENG
China Pharmacy 2016;27(8):1058-1060,1061
OBJECTIVE:To understand the distribution and drug resistance of the pathogens by sputum culture in patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) in our hospital so as to provide reference for rational use of antibiotics. METHODS:From Dec. 2010 to Dec. 2014,the sputum specimens were collected from the AECOPD patients,then the identification of 307 strains of pathogens and drug susceptibility test were carried out,and the data were analyzed statistically by using SPSS 17.0 software. RESULTS:A total of 307 strains of pathogens were collected,of which 17 cases of gram-positive ba-cillus accounted (5.54%),247 cases of gram negative cocci (80.46%),43 cases of fungi accounted (14.00%). The most com-mon isolates from sputum specimens were Pseudomonas aeruginosa (33.22%),Acinetobacter baumannii (19.54%),Stenotroph-omonas maltophilia(9.77%),Klebsiella pneumoniae(7.82%),Candida albicans(6.84%),etc. P. aeruginosa and A. baumannii were highly multidrug-resistant. There were 10 strains of ESBLs-producing K. pneumonia isolated, with the isolation rate of 41.67%. No Staphylococcus aureus strain was found resistant to vancomycin,teicoplanin or linezolid. Methicillin resistant strains in S. aureus(MRSA)accounted for 50.00%. CONCLUSIONS:Gram-negative bacilli are the most common pathogens in the AE-COPD patients. The common species of pathogens are highly resistant. More attention should be paid to the drug resistance monitor-ing of pathogens and rational use of antibiotics according to the results of susceptibility test.
10.Effect of small interference RNA silenced S100A4 protein in human gastric carcinoma cells on proliferation, apoptosis and chemotherapy sensitivity in vitro
Peng LI ; Jiangwei LIU ; Zhenkui HAN
International Journal of Surgery 2016;43(5):300-304,封3
Objective To study the application of small interfering RNA silencing S100A4 protein in human gastric cancer cell BGC-823 proliferation,apoptosis and the effect of chemotherapy sensitivity.Methods Human gastric carcinoma cell line BGC-823 transfection siRNA,RT-PCR detected the changes of mRNA after transfection.Groups divided into interference group,negative control group and normal control group.MTT test determined different concentrations of oxaliplatin in gastric cancer cells and calculated IC50,then draw cell growth curve,TUNEL method to detect apoptosis,RT-PCR tested each cell mRNA changed,Western blot detected the change of the S100A4 protein.All data analysis by SPSS17.0,t test applied,RT-PCR and Western blot results analysis by SPSS17.0,comparing multiple samples by using single factor analysis of variance and LSD test.P < 0.05 was statistically significant.Results RT-PCR results showed that BGC-823 cell transfection,S100A4mRNA expression quantity respectively after 48 hours:(0.674+0.011),(0.652+0.021),(0.345 + 0.040),the interference group and normal control group were statistically significant (P =0.012,P < 0.05) and the negative control group with interference group differences were statistically significant (P =0.000,P < 0.05),and normal control group was no statistically significant difference with the negative control group (P =0.380,P > 0.380);Western blot results showed BGC-823 cell transfection S100A4 expression significantly lowered respectively after 48 hours,there were (0.654 + 0.025),(0.642 + 0.014),(0.317 ± 0.061),the interference group and normal control group was statistically significant (P =0.01,P < 0.05),between negative control group and interference group were statistically significant (P =0.000,P < 0.05),normal control group and the negative control group had no significant difference (P =0.341,P > 0.341).After S100A4-siRNA transfection,gastric carcinoma BGC-823 cell proliferation decreased,TUNEL method showed obviously increase apoptosis,MTY showed that IC5o of oxaliplatin was 56.31 μmol/L,after transfection,IC50 was 0.654 μmol/L.Conclusions This study showed that the siRNA silence S100A4 protein inhibit gastric cancer cell proliferation,induced apoptosis and improved chemotherapy sensitivity of oxaliplatin.S100A4 might be prompt targets for the treatment of gastric carcinoma.