1.Characteristics of medical and health literature novelty assessment in institutions of armed forces, its problems and solutions
Chinese Journal of Medical Library and Information Science 2014;(5):59-61
The characteristics of medical and health literature novel assessment in institutions of armed forces were described from the secrecy of projects for literature novelty assessment , the limitations of consignee institution , and the non-profitability of literature novelty assessment agency .The major problems of medical and health literature novel assessment in institutions of armed forces were elaborated in terms of the literacy, instability, competency and knowledge limitation of literature novel assessment staff with suggestions put forward for their solution such as strengthening the construction of talent team, joint development and sharing of resources.
2.Dynamic changes of biventricular and pulmonary circulatory function and relations among them after left coronary artery ligation in dogs
Chinese Journal of Pathophysiology 1986;0(04):-
In anesthetized and thoracotomized dogs the dynamic changes of biventricular contractility, relaxation, pump function, pulmonary circulatory pressure and resistance were observed and the relations among them were analysed in 2 hours after left anterior descending coronary artery (LAD) ligation. The myocardial ischemic size made by LAD ligation amounted to 35.2?1.4% of left ventricular (LV) mass. After LAD ligation, the decrease of LV relaxation and increase of pulmonary artery pressure happened at first. Then left and right ventricular pump function, LV contractility and right ventricular (RV) relaxation decreased in turn. And pulmonapy vascular resistance increased by a big margin at last. Biventricular pump functions decreased more obviously while pulmonary vascular resistance increased. RV contractility did not change significantly.The results show that the decrease of LV function results in the decrease of RV relaxation directly and RV pump function directly and indirectly by means of increased pulmonary circulatory pressure and resistance but do not effect on RV contractility during early stage of LV myocardial infarction (MI). Factor analysis indicates that the alterations of LV contractility and biventricular pump function are very consistent and play a leading role in the changes of cardiac function after LVMI, the alterations of biventricular relaxation and pulmonary circulatory function take second place in due order.
3.Application and Practice of Network Management Software Based on B/S Structure in HIS
Chinese Medical Equipment Journal 2004;0(09):-
Objective To discover and troubleshoot before user's appeal so as to keep the hospital daily work in order. Methods Through the use of network management software,unified monitoring and management were achieved. Results After many years of practice in information technology,a set of network safety plan was carried out from the system architecture design,implementation and network management. With desirable effect,we keep ahead in this field. Conclusion It is of vital importance to design and carry out effective management based on the practical running of HIS.
4.NS-398 inhibites MVD value and VEGF、MMP-9 expression of hepatocullar carcinoma SMMC-7721 cells and xenograft tissue
Basic & Clinical Medicine 2006;0(10):-
Objective To explore the role of NS-398 on MVD and VEGF、MMP-9 expression of hepatocullar carcinoma.Methods VEGF and MMP-9 expressions were detected by RT-PCR and flow cytometry.Microvascular density of xenograft tissue were detected by immunohistochemical staining and the serum PGE_(2) was detected by ELISA.Results The expression of VEGF and MMP-9 was significantly downregulated in SMMC-7721 cells exposed to(NS-398) in a dose-dependence and time-dependent manner(P
5.A study and evaluation of bacteriophage's utilization in rapid detection of Mycobacterium tuberculosis
Journal of Chongqing Medical University 1986;0(03):-
Objective:To study and evaluate the utilization of bacteriophage in rapid detection of Mycobacterium tuberculosis in clinical samples.Methods:The titer of replicated phage with different methods in 24 or 48 hours were compared,including centrifuge-filter method and incubate-filter method with 0.2?m filter.When the phages were preserved at different conditions with various preservers,the titer was tested and compared in 28 weeks.Other agents of the method,including virucide and help bacteria(Mycobacterium smegmatis) were investigated at different time when they were preserved at 4℃.After the phage assay was established,34 sputum samples were tested by both phage assay and culture method in L-J medium.Based on the results of culture method,phage assay in detection of mycobacterium tuberculosis were evaluated by the sensitivity,specificity and accordance.Results:①The titer of replicated phage was high,when it had been collected after infected for 48 hours.The collection through incubation-filter method was simple and effect.② The phage stored at 4℃ with liquid form was stable,and the declined titer was not more than 101.when the preserver was phage's host bacteria and it was stored at 4℃,it was as stable as that in dehydration form.③The important agents,including virucide and help bacteria,had the same character in 40 weeks,when they were stored at 4℃.④ Compared with the results of culture method,the sensitivity,specificity and accordance of phage assay in rapid detection of mycobacterium tuberculosis were 86.2%,66.7%,and 84.4% respectively.Conclusion:The phage assay could detect viable Mycobacterium tuberculosis of sputum samples in 48 hours.it is feasible to produce testing reagent box from the phage,and can be expected to be used for clinical.
6.On the Building of Curriculum of Public Optional Subjects in Chongqing Medical University
Chinese Journal of Medical Education Research 2005;0(06):-
This paper analyses the current situation of the public optional subjects in Chongqing Medical University,and studies its significance to the curriculum system and teaching reform.The author lays the emphasis on the management of teaching,building of curriculum and enhancement of teaching quality in a medical university.
7.Clinical Observation of Eszopiclone or Zolpidem in the Treatment of Insomnia
China Pharmacy 2007;0(32):-
0.05). CONCLUSION: Eszopiclone has the same clinical efficacy and safety to zolpidem in the treatment of insomnia. The subjective satisfaction of treatment group is higher than control group, and with statistically significance(P
9.Anterior cervical decompression and autograft fusion with plate fixation for treating spondylotic cervical myelopathy(report of 32 cases)
Orthopedic Journal of China 2006;0(09):-
[Objective]To evaluate the clinical effect of anterior cervical decompression and autograft fusion with plate fixation on spondylotic cervical myelopathy.[Methods]From February 2002 to April 2008,32 cases of spondylotic cervical myelopathy were treated with anterior cervical decompression and autograft fusion with plate fixation.During the follow-up,the effect of fusion was observed for 12 months,complications were observed,and the results were evaluated by JOA.[Results]Thirty-two patients were followed up for 6~24months(15 months on average).Symptoms after operation were apparently found or cured.The JOA grade raised from 7~10 before operation(average 8.6) to 12~14(average 12.8) after treatment.The mean time for interbody fusion were 12 weeks,and its effective rate was 100 %.Cervical hematoma was found 3 hours postoperatively in 1 case,and symptom was relived after drainage treatment.Screw loosening was found after operation in another case,solid fusion of the fixation segment was achieved after external fixation for 6 months.[Conclusion]Spondylotic cervical myelopathy patients can be treated through the surgical method with anterior cervical decompression and autograft fusion with plate fixation.The method can release the anterior pressure on the spinal cord,and significantly increase the rate of interbody fusion.
10.Expression of P27~kipl and mutant P53 protein in thyroid tumors
Academic Journal of Second Military Medical University 2000;0(11):-
Objective:To study the expression of P27kipl and mutant P53 protein in thyroid tumors, and to understand the relationship between the biological behavior and prognosis of benign and malignant thyroid tumors. Methods: We used S-P immunohistochemical technique to study the expression of P27kipl and mutant P53 protein in 60 cases of thyroid tumors, including 40 cases of malignant tumors and 20 cases of benign tumors. Categorical data were analyzed by using X2 tests. All reported significance levels were two-tails. The software system used for statistical analysis was SPSS10. 0. Results: In benign and malignant tumors, P27kipl protein positive expression was detected in 18 of 20 benign cases (90. 0%) and 24 of 40 malignant cases (60. 0% ) respectively(P P