Objective: To investigate the clinical efficacy of acupuncture plus auricular plaster therapy for treating migraine. Methods: One hundred and fifty migraine patients were randomly allocated to an observation group (n=90) and a control group (n=60). The observation group were treated by acupuncture plus auricular plaster therapy based on syndrome differentiation and the control group, by oral administration of Flunarizine. The curative effects were compared between the two groups. Results: The total efficacy rate was 94.4% in the observation group and higher than in the control group (73.3%). The recovery rate was 87.8% in the observation group and higher than in the control group (55.0%). There were significant differences between the two groups (both P＜0.01). The curative effect was significantly better in the observation group than in the control group. Conclusion: Clinically, acupuncture plus auricular plaster therapy based on syndrome differentiation has a good effect on migraine.

Altogether 128 cases were treated with comprehensive therapy of electroacupuncture,point-toward point and plaster of auricular points based on syndrome differentiation, and the result showed that the total effective rate was 92.2% and there was no significant difference in the total effective rate among different syndrome patterns (P ＞ 0.05), which indicated that satisfactory results can be obtained through comprehensive therapy including electroacupuncture, point-toward-point and plaster of auricular points based on syndrome differentiation.

To investigate the therapeutic effect of primary refractory trigeminal neuralgia. Methods: Twenty-eight cases of primary trigeminal neuralgia were treated by point penetrating injection plus ear pressing, controlled by 28 cases treated only by acupuncture.Results: The total effective rate was 96.43% in observation group and 78.57% in control group.There wasa significant difference in the total effective rate between the two groups (P＜0.05).Results: Point penetrating injection plus ear pressing is the effective method in treating primary trigeminal neuralgia.

Objective: To study the clinical efficacy of acupuncture plus ear-points pressure for insomnia. Method: All 156 cases were randomized into the observation, acupuncture and Chinese herbal formula groups. Combined acupuncture and ear-points pressure, acupuncture alone and Chinese herbal formula were applied in each group respectively. Result: The total effective rates of the observation, acupuncture and herbal group were 94.2%, 75.0% and 78.8% respectively. This has indicated that combined acupuncture and Auricular Point Sticking could obtain significantly better effect than the acupuncture group (P＜0.01) and the herbal group (P＜0.05). Conclusion: Combined acupuncture and ear-point pressure can obtain a better effect for treatment of insomnia.

0.05),but there was a significantly difference in parameters between the nasal obstruction side and the no obstruction side in patients with nose deformities (P0.05). CONCLUSION The results indicate that acoustic rhinometry has great value in evaluation of patients with nasal deformities before operation and can provide clinical value for the evaluation of nasal function and geometrical structure.

Ninety-eight patients of facial paralysis were treated by acupuncture plus microwave irradiating the postauricle area and Ashi point. After 3 courses of treatment, 71 cases were cured, 26 cases got improvement and 1 case obtained no effect.

OBJECTIVE: This study was designed to develop a rating scale of quality of life (QOL) which fits laryngeal cancer patients after laryngectomy. METHOD: The item pool was developed on the definition of QOL from WHO and the principles and procedures of ddveloping a rating scale. Five methods had been used in the item selection including, such as subjective evaluation methods, discrete tendency, correlation coefficient method, stepwise regression analysis, and factor analysis. The survey was conducted in 126 laryngeal cancer patients after laryngectomy in order to assess the reliability and validity of the rating scale. RESULT: (1) A rating scale of QOL which fits laryngeal cancer patients after laryngectomy including six domains and 27 items is was developed. (2) The split-half reliability coefficient of the scale is 0.802, and the Cronbach' α coefficient is 0.794. (3) It is inferred from the correlation analysis that there are strong correlation between items and their own domains; conversely there are weak correlation between items and other domains. Correlation coefficient is 0.731 between total score and self-rating score. CONCLUSION The reliability and validity of the rating scale is proved to work well.
Aged ; Factor Analysis, Statistical ; Female ; Humans ; Laryngeal Neoplasms ; surgery ; Laryngectomy ; Male ; Middle Aged ; Postoperative Period ; Quality of Life ; Regression Analysis ; Reproducibility of Results

Objective To explore the feasibility and effects of one stage vascular free fibular transplantation or combination of bone transport two-stage technique for reconstruction of adversity congenital pseudarthrosis of the tibia. Methods Vascularised free fibular reconstruction operations for adversity congenital pseudarthrosis of tibia were performed in 16 cases, including male in 9 and female in 7,age ranged from 6 to 14 years with the mean in 8.5 years. 2 to 6 operations history were documented in all cases with the mean in 3.2 before went to our hospital, with 3 to 12 cm and mean 5.8 em short of the tibia. Mean9.2 cm (from 6.0 to 16.0 cm) vascular free fibular were harvested and transplanted to reconstruct the bone frame in 16 cases, bone transport operation were performed in 4 cases 1 year later. Results Fourteen cases were followed up for mean 4.5 years, bone union could be found by radiology examination, mean 7.8cm (from 4.0 to 11.5 cm) elongation of the low limb were obtained in 4 cases. Basic walking function was obtained in all cases. Conclusion It is an effective method to treat adversity congenital psuedarthrosis of the tibia by thoroughly resection of the focus and enough length of vascular fibular transplantation, deficiency of low limb can be ameliorated by bone transportation technique in those patients.

ObjectiveEvidence-based medicine was used to make an individualized treatment plan for rare solitary splenic metastasis of an ovarian carcinoma in a female patient. MethodsAfter clinical problems were discovered, evidence was collected from the Cochrane Library, PubMed, EMBASE, ScienceDirect, CNKI and Wanfang databases according to our predefined search strategy. The search was done until October, 2009. The validity of the evidence was assessed. The evidence, combined with the doctor experience and the patient value, was applied to the patient. ResultsA total of 15 English literature and 11 Chinese literature were identified. A rational treatment plan was made upon a critical evaluation of the data. There were 5 review articles in PubMed, EMBASE and ScienceDirect databases and no RCT in the Cochrane Library. And there was one retrospective cohort study inCNKI and Wanfang databases. The others were all case reports. After 20 month follow-up, the treatment protocol was proven correct. Conclusion The patient has rare disease, and the evidence intension for the evidence-based medicine was low. It can not present the efficacy of the evidence-based medicine treatment sufficiently, though it could provide some suggestion for rare disease which was lack of large RCT for evidence-based Methods .

OBJECTIVE: To discuss the treatment of H3R agonist, IMETIT, on the allergic rhinitis(AR) ,and the influence to mRNA of Substance P(SP) and Substance P Receptor (SP-R) in AR model of guinea pigs. METHOD: The severity of AR was assessed by allergic symptoms (sneezing, nasal rubbing and nose blocking). The changes in the nasal mucosa were studied by pathological methods. The expression of SP positive cell was detected by immunohistochemistry, and the expression of SP-R mRNA was detected by reverse transcriptive polymerase chain reaction (RT-PCR). RESULT: Histamine H3R agonists, IMETIT can effectively improve the AR symptoms, sneezing, nasal itching, nasal congestion, reduce the pathological changes in the nasal mucosa, cut down the SP secretion and SP-R mRNA expression. CONCLUSION Histamine H3R agonist, IMETIT can effectively relieve the symptoms of AR in guinea pigs, which is related to reducing SP secretion and SP-R mRNA expression.
Animals ; Female ; Guinea Pigs ; Imidazoles ; therapeutic use ; Male ; Receptors, Histamine H3 ; drug effects ; Receptors, Neurokinin-1 ; genetics ; metabolism ; Rhinitis, Allergic, Perennial ; drug therapy ; metabolism ; Substance P ; metabolism ; Thiourea ; analogs & derivatives ; therapeutic use