1.Discussion on theEthical Issues Involved in Cardiac Interventional Therapy
Chinese Medical Ethics 2016;29(5):810-811
This paper introduced the current situation of cardiac interventional therapy and put forward the fol-lowing points that medical staffs should pay attention to:the patient's right to know, right to be informed, right of communication, right of privacy, and etc. On this basis, it is suggested to solve the ethical issues in cardiac inter-ventional therapy through the implementation of clinical pathway, effective communication, humanistic care, the construction of occupational ethics, strict feedback and supervision.
5.Progress of signal transduction pathway of gastrin stimulating proliferation of colorectal carcinoma cells
Chinese Journal of Clinical Pharmacology and Therapeutics 2004;0(11):-
Recent studies indicate that there are expressions of gastrin and its receptors in the tissue and cell line of colorectal cancer .Gastrin stimulates the proliferation of colorectal carcinoma as well as inhibits the apoptosis of colorectal carcinoma so as to promote the growth and invasion of colorectal carcinoma via a series of signal transduction pathways induced by its specific receptors. To inhibit the abnormally active signal transduction pathways that stimulate the proliferation of colorectal carcinoma will provide a new effective measure for the prevention and management of colorectal carcinoma.But the accurate signal transductions are not clear and need further research.
6.Effect of Acupoint Sticking at“Zusanli”(ST36) with Magnolia Powder on Patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease and Gastrointestinal Dysfunction
Journal of Zhejiang Chinese Medical University 2013;(10):1259-1260,1264
[Objective] To observe the effect of acupoint sticking at“Zusanli”(ST36) with magnolia powder on patients with acute exacerbations of chronic obstructive pulmonary disease and gastrointestinal dysfunction. [Method] A total of 78 patients with acute exacerbations of chronic obstructive pulmonary disease(AECOPD) and gastrointestinal dysfunction were randomly divided into two groups: treatment group(n=40) and control group(n=38). Al patients received conventional therapy for AECOPD and tablet mosapride 5mg tid for 3 days. Patients in treatment group also received acupoint sticking at“Zu-sanli”(ST36) with magnolia powder q8h for 3 days. [Result]The total effective rate was 75.0%for treatment group,and 44.7%for control group. The total effective rate of treatment group was higher than that of control group, and no marked side effects were found. [Conclusion] Acupoint sticking at“Zusan-li”(ST36) with magnolia powder combined with mosapride can relieve gastrointestinal dysfunction of patients with AECOPD.
7.Observation of TCM Syndromes of 200 Cases of Upper Airway Cough Syndrome
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(06):-
Objective To research the pattern distribution of TCM syndromes in upper airway cough syndrome(UACS)(source of the nose).Methods Two hundred cases of UACS(source of the nose) were observed to analyze the pattern distribution of TCM syndromes.Result The pattern distribution of TCM syndromes was as follows:wind-phlegm obstruction lung syndrome 76 cases(38%),wind-phlegm and stagnant heat syndrome 58 cases(29%),wind-cold and dampness syndrome 34 cases(17%),lung dry and Yin deficiency syndorme 32 cases(16%).Analysis of nose diseases history and TCM syndrome type showed that allergic rhinitis,chronic nasosinusitis and non-allergic rhinitis were main causes of UACS(source of the nose),account for 46.0%,25.5% and 14.5% respectively.Conclusion Wind-phlegm obstruction lung syndrome and wind-phlegm and stagnant heat syndrome were the most common syndromes of UACS.
9.Effect of Shenfu Injection on QRS Complex in Patients with Chronic Heart Failure
Qiang PEI ; Xide ZHAO ; Wenfeng SANG
Herald of Medicine 2014;(11):1470-1473
Objective To investigate the relationship among electrocardiogram QRS complex duration,left ventricular ejection fraction( LVEF),N-terminal pro-brain natriuretic peptide( NT-proBNP)and their relation to New York Heart Association (NYHA)functional classification in patients with chronic heart failure(CHF),and observe the intervention effects of Shenfu injection(SFI)on patients with CHF. Methods A total of 72 CHF patients were randomly assigned to treatment group(36 cases)and control group(36 cases). Patients in the control group received standard care,and those in the treatment group received standard care plus 1. 0 mL·kg-1 ·d-1 of SFI in 5% glucose for two weeks. Before and after the treatments,the electrocardiogram QRS complex duration,LVEF,NT-proBNP were measured and NYHA functional classification was evaluated. Results Electrocardiogram QRS complex duration was negatively correlated with LVEF and was positively correlated with NT-proBNP and NYHA functional classification( P〈0. 05 ). After the treatment,the proportion of patients with NYHA classⅠ-Ⅱsignificantly increased and classⅢ-Ⅳsignificantly decreased in both groups. The treatment group was superior to the control group in reinstating cardiac function( P〈0. 05 ). After the treatment,electrocardiogram QRS complex duration and the levels of NT-proBNP were significantly descended and LVEF were significantly ascended in both groups(P〈0. 05). The level of NT-proBNP in the treatment group was significantly lower than in the control group(P〈0. 05),but electrocardiogram QRS complex duration and LVEF did not show significant difference. The prior-and post-treatment difference in electrocardiogram QRS complex duration and LVEF was more obvious in the treatment group than in the control(P〈0. 05). Conclusion The extension of electrocardiogram QRS complex duration is correlated with plasma NT-proBNP elevation and cardiac dysfunction,which can be used as a reference for disease progression or medication efficacy. SFI is effective on CHF of the yang-qi deficiency type.
10.Autogenous bone graft harvested from trephination for arthrodesis of one single cervical intervertebral space following decompression
Chinese Journal of Orthopaedics 2000;0(11):-
Objective To investigate whether the bone harvested from Cloward discectomy with trephine could substitute for iliac-crest bone grafts in arthrodesis procedure. Methods We reviewed the 30 patients with cervical spondylotic myelopathy involving a single level, which had been managed with anterior trephination discectomy and arthrodesis by the bone chips harvested from within the trephine. The bone chips harvested with trephine were then trimed and implanted erectedly similar to Robinson arthrodesis procedure. All cases had been followed-up for an average of 4.75 years. The latest results were analyzed according to JOA score system and recovery rate. The fusion outcome were assessed by anteroposterior and flexion and extension lateral radiographs of the cervical spine. Results At the latest followed-up examination, clinical results were excellent in fifteen patients(50% ), good in eleven(36.7% ), fair in three(10% ) and poor in one (3.3% ). X-ray showed solid fusion in all, and no dislodgment of the grafts. However, the cervical curves had a little loss. There was no significant bone grafts subsidence. Conclusion In cervical anterior decompression the bone chips obtained in trephination could substitute for other type of bone grafts for arthrodesis. The postoperative outcomes were not affected by the loss of the cervical curves.