BACKGROUND:The distance of spinal cord shifting backward after treatment through cervical posterior approach is affected by various factors. In fact, it is a morphological change after spinal cord is affected by external force.
OBJECTIVE:To analyze the influential factors for spinal cord shifting backward after posterior cervical decompression for cervical spondylotic myelopathy.
METHODS:Case data of 70 patients with multi-segmental cervical spondylotic myelopathy undergoing posterior cervical decompression were retrospectively analyzed. According to the different distances of spinal cord shifting backward after treatment, they were divided into three groups:<3 mm group, 3-5 mm group, and>5 mm group. In accordance with Japanese Orthopaedic Association Scores, the degree of cervical curvature and axial symptom index were compared.
RESULTS AND CONCLUSION:No significant difference in the recovery rate of Japanese Orthopaedic Association Scores was detected among the three groups. No significant difference in cervical curvature was visible among the three groups before and after treatment. The proportion of axial symptom was significantly higher in the patients of>5 mm group than the other two groups after treatment (P<0.05). These results suggested that the distance of spinal cord shifting backward was associated with axial symptom after treatment in patients with cervical spondylotic myelopathy after posterior cervical decompression.

In recent years, neuro-electrophysiological techniques, as objective evaluation methods, have been gradually used in func-tional evaluation, guiding clinical rehabilitation programs and judging prognosis after stroke. They were proved to judge the integrity of cen-tral nervous system and conduction function and evaluate neuromuscular function. Nerve conduction, needle electromyography, H reflex, F wave, sympathetic skin response, motor-evoked potentials, somatosensory-evoked potentials, brain stem auditory-evoked potentials and sur-face electromyography were reviewed in this article.

In the paper, by taking acupuncture and migraine as the key words to retrieve CNKI and PubMed database, the literature analysis was done on the mechanism study on experimental migraine treated with acupuncture in rat model. The results showed that acupuncture mechanism study focused on the regulation and control of the relevant neurotransmitters/neuromodulators of migraine, such as calcitonin gene-related peptide (CGRP), serotonin (5-HT), nitric oxide (NO), etc. Moreover, in the paper, the review had been done on the neurotransmitters/neuromodulators involved in the study.
Acupuncture Points ; Acupuncture Therapy ; Animals ; Disease Models, Animal ; Humans ; Migraine Disorders ; genetics ; metabolism ; therapy ; Nitroglycerin ; metabolism ; Rats ; Serotonin ; metabolism

Objective: To investigate the chemical constituents in the dried whole plant of Lobelia chinensis. Methods: Column chromatography, such as silica gel, MCI, ODS, Sephadex LH-20, C18 reverse-phased silica gel columns, and preparative HPLC were used to isolate the compounds. Spectroscopic methods like MS, 1H-NMR, and 13C-NMR were used to elucidate their structures. Results: Fifteen compounds were isolated from 95% ethanol extract of L. chinensis, including twelve flavonoids: quercetin (1), rutin (2), luteolin (3), apigenin (4), hesperidin (5), quercetin-3-O-α-L-rhamnoside (6), quercetin-7-O-α-L-rhamnoside (7), quercetin-3- O-β-D-glucoside (8), amentoflavone (9), naringenin (10), hesperetin (11), and eupafolin (12), and three coumarins: 5, 7- dimethoxy-coumarin (13), isoscopoletin (14), and scoparone (15). Conclusion: Compounds 6-12 are isolated from the plants in genus Lobelia L. for the first time. Compounds 5, 13, and 14 are isolated from L. chinensis for the first time.

Pancreatic cancer has a strong ability of invasive and metastasis,and the mechanism is still not completely clear.It has been demonstrated that aberrant expression of microRNAs(miRNA) is closely associated with the occurrence,development and metastasis of pancreatic cancer.The reveal of miRNA mechanism related to the metastasis of pancreatic cancer would provide a new approach to the treatment of pancreatic cancer.

Objective To analyze functional improvement of spinal cord and the prognosis of two surgical approaches for the stenosis of cervical spinal canal;to investigate the mechanisms concerning post-terior decompression,fusion with ilium graft and internal fixation and 158 cases who underwent dorsal laminectomy from January 2001 to October 2002 were follow-up for at least 24 months and examined with the evaluation systems of Japanese Orthopaedic Association Score,somatosensary evoked essential and initiative range of motion to compare preoperative,short-term and long-term efficacy.Results According to selected standard of improvement rate,therapeutic effect of 56 sufferers among ventral approach group was analyzed,14 cases(25%)excellent,29 cases(51.79%)good,10 cases(17.86%)fair,3 cases(5.36%)poor;postoperative effect of 62 sufferers from dorsal approach group was analyzed,23 cases(37.10%)excellent,31 cases(50%)good,7 cases(11.29%)fair,1 case(1.61%)poor.Concerning JOA evaluation of spinal cord function,initiative range of motion and correlated parameters of SEP,there was significant difference between two decompression approach in postoperative periods.7 cases from anterior approach and 13 patients from posterior approach disturbed by postoperative complications were gradually rehabilitated through conservative of Cervical 5 spinal root',the essence of above-mentioned symptoms may be cervical cord impairment due to decompression process,which would be alleviated by appropriate intervention;2)The efficiency of posterior decompression get the better of anterior decompression in light of fundamentally enlarging available space approach became a little smaller than normal individuals,however,the corresponding parameters after anterior approach lower than the former two groups.

Many trauma victims occur in China every year, with a notably high mortality rate among those who suffered from multiple traumas such as severe traffic trauma. One of the main reasons is the defect of current trauma emergency system, in which the full-time trauma physician often lacks. It has therefore become urgent to establish a well-organized trauma emergency system with full-time physicians.
Accidents, Traffic ; statistics & numerical data ; China ; Emergency Service, Hospital ; manpower ; organization & administration ; standards ; Humans ; Multiple Trauma ; epidemiology ; Physicians ; supply & distribution

normal group, and the difference of bone mineral density was significant between two groups with lumbar spines and trochanter (P 0.05).③Osteoporosis grouping: The risk factors of osteoporosis may be found only in BMI between the two groups, and the difference was statistically significant (P

Objective:To study the effect of various extract of Sini Decoction on hypothalamus-pituitary-sexual glands axle of hypothyroidism rats with syndrome of yang deficiency, and discuss the mechanism of Sini Decoction in reinforcing yang. Methods: The model of deficiency of both the spleen-yang and the kidney-yang were induced by PTU solution. After the model were confirmed, the rats in Sini Decoction group were administered with Sini Decoction . At the end of the experiment, all the rats were sacrificed and the blood were sampled to check the level of Sex hormones , the reproductive organs were weighed, the testicle were sliced to check their pathological change. Results:Various extract of Sini Decoction can reduce the increase of weight of orchis and prostate of model rats, reduce their pathologic damage, and increase the level of testosterone. The alcohol extract of Sini Decoction has obvious therapetic effects. Conclusion: Sini Decoction can improve the sexual hormone level and weight index of reproductive organs of hypothyroidism rats with syndrome of yang defi ciency.

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β(TGF-β) superfamily and play critical roles in skeletal development, bone formation and stem cell differentiation.BMP9 is one of the most osteogenic BMPs, promoting osteogenesis differentiation of periodontal ligament stem cells ( PDLSCs) both in vitro and in vivo.Recently, signal transduc-tion studies have revealed that BMP-Receptor-Smads and BMP-Receptor-Mitogen activated protein kinase ( MAPK) play vital roles in BMP9 which promote PDLSCs osteogenesis differentiation.Several studies revealed that transcription factors closely associated with os-teogenesis differentiation are found in the downstream of the Smads and MAPK pathways.This review aims to summarize our current knowledge of BMP9-mediated osteogenesis by presenting recently completed works which may help us to further elucidate these path-ways.