BACKGROUND:The distance of spinal cord shifting backward after treatment through cervical posterior approach is affected by various factors. In fact, it is a morphological change after spinal cord is affected by external force.
OBJECTIVE:To analyze the influential factors for spinal cord shifting backward after posterior cervical decompression for cervical spondylotic myelopathy.
METHODS:Case data of 70 patients with multi-segmental cervical spondylotic myelopathy undergoing posterior cervical decompression were retrospectively analyzed. According to the different distances of spinal cord shifting backward after treatment, they were divided into three groups:<3 mm group, 3-5 mm group, and>5 mm group. In accordance with Japanese Orthopaedic Association Scores, the degree of cervical curvature and axial symptom index were compared.
RESULTS AND CONCLUSION:No significant difference in the recovery rate of Japanese Orthopaedic Association Scores was detected among the three groups. No significant difference in cervical curvature was visible among the three groups before and after treatment. The proportion of axial symptom was significantly higher in the patients of>5 mm group than the other two groups after treatment (P<0.05). These results suggested that the distance of spinal cord shifting backward was associated with axial symptom after treatment in patients with cervical spondylotic myelopathy after posterior cervical decompression.

In recent years, neuro-electrophysiological techniques, as objective evaluation methods, have been gradually used in func-tional evaluation, guiding clinical rehabilitation programs and judging prognosis after stroke. They were proved to judge the integrity of cen-tral nervous system and conduction function and evaluate neuromuscular function. Nerve conduction, needle electromyography, H reflex, F wave, sympathetic skin response, motor-evoked potentials, somatosensory-evoked potentials, brain stem auditory-evoked potentials and sur-face electromyography were reviewed in this article.

In the paper, by taking acupuncture and migraine as the key words to retrieve CNKI and PubMed database, the literature analysis was done on the mechanism study on experimental migraine treated with acupuncture in rat model. The results showed that acupuncture mechanism study focused on the regulation and control of the relevant neurotransmitters/neuromodulators of migraine, such as calcitonin gene-related peptide (CGRP), serotonin (5-HT), nitric oxide (NO), etc. Moreover, in the paper, the review had been done on the neurotransmitters/neuromodulators involved in the study.
Acupuncture Points ; Acupuncture Therapy ; Animals ; Disease Models, Animal ; Humans ; Migraine Disorders ; genetics ; metabolism ; therapy ; Nitroglycerin ; metabolism ; Rats ; Serotonin ; metabolism

Objective: To investigate the chemical constituents in the dried whole plant of Lobelia chinensis. Methods: Column chromatography, such as silica gel, MCI, ODS, Sephadex LH-20, C18 reverse-phased silica gel columns, and preparative HPLC were used to isolate the compounds. Spectroscopic methods like MS, 1H-NMR, and 13C-NMR were used to elucidate their structures. Results: Fifteen compounds were isolated from 95% ethanol extract of L. chinensis, including twelve flavonoids: quercetin (1), rutin (2), luteolin (3), apigenin (4), hesperidin (5), quercetin-3-O-α-L-rhamnoside (6), quercetin-7-O-α-L-rhamnoside (7), quercetin-3- O-β-D-glucoside (8), amentoflavone (9), naringenin (10), hesperetin (11), and eupafolin (12), and three coumarins: 5, 7- dimethoxy-coumarin (13), isoscopoletin (14), and scoparone (15). Conclusion: Compounds 6-12 are isolated from the plants in genus Lobelia L. for the first time. Compounds 5, 13, and 14 are isolated from L. chinensis for the first time.

Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β(TGF-β) superfamily and play critical roles in skeletal development, bone formation and stem cell differentiation.BMP9 is one of the most osteogenic BMPs, promoting osteogenesis differentiation of periodontal ligament stem cells ( PDLSCs) both in vitro and in vivo.Recently, signal transduc-tion studies have revealed that BMP-Receptor-Smads and BMP-Receptor-Mitogen activated protein kinase ( MAPK) play vital roles in BMP9 which promote PDLSCs osteogenesis differentiation.Several studies revealed that transcription factors closely associated with os-teogenesis differentiation are found in the downstream of the Smads and MAPK pathways.This review aims to summarize our current knowledge of BMP9-mediated osteogenesis by presenting recently completed works which may help us to further elucidate these path-ways.

Objective To observe the effect of transformation of vascularized tissue-engineered bone with vascular bundle graft in vivo. Methods The bone marrow stem cells (BMSCs) obtained from rabbit os ilium were cultured, expanded and induced to form osteocytes, then they were combined with porous ?-tricalcium phosphate (?-TCP) to construct tissue-engineered bone. The tissue-engineered bone was implanted in a segmental defect with critical length of 15mm in rabbit femoral shaft. A bundle containing both artery and vein was inserted in the centre of the tissue-engineered bone with microvascular surgical technique. After an examination with DEXA bone scanner, the specimen was harvested for macroscopic and histological examination after 12 weeks of growth period. Results The site where the implanted vascular bundle inserted into the tissue engineered bone appeared like foramen nutriens, the blood vessels were patent. Abundant blood vessels, which emerged from the deep tissue of the engineered bone, were evident on the surface of specimen. Multicentric ossification area rich in blood vessels could be seen in the tissue-engineered bone histologically. The enchondral ossification in the center of tissue-engineered bone and membranous ossification in the periphery occurred simultaneously. Some materials in the centre of tissue-engineered bone had transformed into marrow cavity like construction. The results of the DEXA demonstrated that the vascularized tissue-engineered bone produced more boney tissue. Conclusions Implantation of blood vessel bundle into tissue-engineered bone may enhance neovascularization of the tissue-engineered bone and accelerate the process of reconstruction subsequently, and it is a promising method of vascularization of tissue-engineered bone.

Field medical equipment is important material base of medical service in wartime and one organic part of medical care scheme in echelon. However, medical service under hot and humid environment (HHE) is characterized by some new features due to the dual influences of environmental factor and war injury itself, which might bring certain challengeable demands on medical equipment development. As one part of medical care scheme in echelon under HHE, this paper presents a general study on demands of field medical equipment under HHE aimed to provide references for demonstration, research and development of medical equipment of Chinese PLA in the future.

Objective:To study the effect of various extract of Sini Decoction on hypothalamus-pituitary-sexual glands axle of hypothyroidism rats with syndrome of yang deficiency, and discuss the mechanism of Sini Decoction in reinforcing yang. Methods: The model of deficiency of both the spleen-yang and the kidney-yang were induced by PTU solution. After the model were confirmed, the rats in Sini Decoction group were administered with Sini Decoction . At the end of the experiment, all the rats were sacrificed and the blood were sampled to check the level of Sex hormones , the reproductive organs were weighed, the testicle were sliced to check their pathological change. Results:Various extract of Sini Decoction can reduce the increase of weight of orchis and prostate of model rats, reduce their pathologic damage, and increase the level of testosterone. The alcohol extract of Sini Decoction has obvious therapetic effects. Conclusion: Sini Decoction can improve the sexual hormone level and weight index of reproductive organs of hypothyroidism rats with syndrome of yang defi ciency.

Organophosphate pesticides(OPs)are used extensively in agriculture,it became the most heavily used insecticides in China after the use of organochlorine pesticide was restricted in 1980s in China.Recent years,with an increasing usage of organophosphate pesticides in China,much concern has been showed for the level of OPs in human body and the adverse effects of OPs on human health especially on fetuses and children have raised a great.The level of OPs in children and the adverse effects of OPs exposure on neurobehavioral development of children were reviewed in the present article.