Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.

Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.

Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.

Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.

Drowning is the third most common cause of accidental death in children. Various predictors for survival and neurological dysfunction include the age of victim, submersion time, salt versus fresh water, temperature of water, cardiopulmonary resuscitation at the scene, and time required to hospital arrival. Autonomic dysfunction, in particular heart rate variability in a critically ill patient, has been attributed to good neurological outcomes. We hereby describe a 10-year-old boy who accidentally drowned and developed a substantial heart rate variability with autonomic dysfunction. He was in the need for prolonged vasopressor support but eventually had a good neurological outcome.

The exocrine part of the pancreas has a duct system called the pancreatic ductal system (PDS). Its mechanism of development is complex, and any reorganization during early embryogenesis can give rise to anatomical variants. The aim of this study is to collect, classify, and analyze published evidence on the importance of anatomical variants of the PDS, addressing gaps in our understanding of such variations. The MEDLINE, Web of Science, Embase, and Google Scholar databases were searched to identify publications relevant to this review. R studio with meta-package was used for data extraction, risk of bias estimation, and statistical analysis. A total of 64 studies out of 1,778 proved suitable for this review and metanalysis. The meta-analysis computed the prevalence of normal variants of the PDS (92% of 10,514 subjects). Type 3 variants and “descending” subtypes of the main pancreatic duct (MPD) predominated in the pooled samples. The mean lengths of the MPD and accessory pancreatic duct (APD) were 16.53 cm and 3.36 cm, respectively. The mean diameters of the MPD at the head and the APD were 3.43 mm and 1.69 mm, respectively. The APD was present in only 41% of samples, and the long type predominated. The pancreatic ductal anatomy is highly variable, and the incorrect identification of variants may be challenging for surgeons during ductal anastomosis with gut, failure to which may often cause ductal obstruction or pseudocysts formation.

Studies reveal variations in the in the origin, number, and branching patterns of the lateral circumflex femoral artery (LCFA). The present study aimed to document such variations and their potential clinical applicability. Thirty-two femoral triangles of 16 embalmed adult human cadavers were dissected to investigate the variation in the origin, number, and branching patterns of LCFA. The main branches of the LCFA were tracked independently for numerical variations in branching pattern. The distance between the origin of LCFA and mid inguinal point (MIP) was also measured in each case.LCFA was most commonly arising from profunda femoris (PF), followed by femoral artery (FA) and common trunk of the femoral artery (CFA). Duplication LCFA was observed in 15 (46.87%) limbs, in 5 (31.25%) cases duplication was only on right side, in 4 (25%) cases duplication was only on left side and in 3 (18.75%), duplication was bilateral. Cases with duplication of LCFA, showed numerical variations with descending pattern being the most common. The average distance of LCFA1 and LCFA2 from mid-inguinal point was 5.77±1.35 cm and 6.14±2.05 cm respectively. Detailed information regarding the occurrence of duplication will be great importance for surgeons, interventional radiologists, and other medical professionals performing procedures in the femoral region. Knowledge of variation of branching pattern of LCFA is utmost important as surgeons use the descending branch of the LCFA in bypass grafting and vascular reconstruction surgeries.

The liver is the largest gland of the gastrointestinal tract having both exocrine and endocrine functions.Developmentally it arises as a ventral outgrowth from the gut endoderm during 3rd week of intrauterine life. The foetal liver is very important because of its synthetic and hemopoietic potential. The present work aimed to see the detailed histogenesis and development of the foetal liver by cytological, immunohistochemical and ultrastructural study. The liver tissue of nine aborted foetuses of various gestational age were studied. For cytology: special stains like Masson trichrome, periodic acid Schiff and reticulin were used, immunohistochemical staining was performed with triple antibodies (c-myc, Ki-67 and Ber-H2), and for ultrastructure: aluminium mounted specimens were coated with gold and argon gas and observed under scanning electron microscopy (EM). Cytology and immunohistochemistry showed the development of duct patterns and hemopoietic patterns in all stages of fetogenesis. The ductal plate was marked by the layer of dark brown staining cells at the edge of two portal tracts. The haemopoietic cells with sinusoids and aggregation of hepatocytes were observed in the early weeks of gestation. EM showed tree-like branching of a portal canal depicting hepatic segmentation of foetal liver.The organizational changes in lobular pattern, duct pattern, and microstructure of liver during fetogenesis are very crucial to achieve the adult morphology in feature. Histogenesis of the foetal liver follows a multistep process depending upon the gestational age, any deviation from normalcy may lead to structural and functional abnormality later in life.