1.Lessons Learned from a Fulminant Case of Reversible Cerebral Vasoconstriction Syndrome: Past Medical History Misleads the Diagnosis and Intra-Arterial Milrinone Offers Diagnostic Utility
Paul J ALAPATT ; Ajay PANWAR ; Gigy Varkey KURUTTUKULAM ; Kaushik SUNDAR
Neurointervention 2021;16(1):78-82
A 34-year-old post-partum female having dermatomyositis developed headache and became comatose after a seizure episode. Magnetic resonance imaging of brain showed a massive left ganglio-capsular bleed for which decompressive surgery was done. Computed tomographic angiography showed multiple foci of narrowing and irregularities in distal cerebral vessels. In view of dermatomyositis, the diagnosis of vasculitis was considered and pulse therapy of intravenous methylprednisolone was started. The patient, however, showed no improvement and developed new brain infarcts. She was subsequently taken up for a diagnostic cerebral angiography which showed multifocal severe narrowing in bilateral major cerebral arteries. These angiographic abnormalities showed excellent reversibility to intra-arterial milrinone and hence, reversible cerebral vasoconstriction syndrome (RCVS) was diagnosed. Normal angiographic findings in the first week do not rule out the disease and a repeat angiography should be considered if the clinical suspicion of the RCVS is high. Intra-arterial milrinone has a high diagnostic utility.
2.Estimation of Diameter of Quadrupled Hamstring Graft for ACL Reconstruction using Pre-operative MRI Measurement as a Predictive Tool
Kuruvilla RS ; Gunasekaran C ; Jepegnanam TS ; Kandagaddala M ; Panwar J
Malaysian Orthopaedic Journal 2024;18(No.1):91-98
Introduction: The diameter of the quadrupled Hamstring
graft plays a significant role in the incidence of graft failures
for ACL reconstruction. The ability to predict the graft size
pre-operatively can prepare the surgeon for alternatives in
the event of an inadequate graft diameter.
Materials and methods: We retrospectively measured the
diameter of the Semitendinosus tendon (ST) on the MRI in
all patients who underwent arthroscopic ACL reconstruction
using quadrupled Semitendinosus as their graft. We also
estimated any correlation between various anthropometric
data with pre-operative MRI based Cross Sectional Area
(CSA) of the Hamstring tendon and final graft diameter in
the South Asian population. The patients were included from
Jan 2018 - Dec 2020.
Results: The minimum CSA of ST to predict an eventual
graft diameter of 7.5mm was 10.7mm2
. The MRI based
cross-sectional area measurement showed moderate
correlation with the intra-operative graft diameter obtained.
(r=0.62, p<0.001). The intra-class correlation coefficient
between the radiologist and the surgeon was 0.82, 95% CI
(0.57, 0.92) and a p-value <0.001.
Conclusion: Pre-operative MRI can be a useful tool to
predict the graft diameter. This coupled with the
anthropometric data of the patient can be used as an adjunct
to estimate the probable graft diameter. Thus, the surgeon
can be better prepared for the surgery and can seek alternate
graft options if the graft size is deemed inadequate preoperatively.