〔Abstract〕 Based on various visual softwares, the paper mines the data of SCI papers and published patents on Eastern Equine En-cephalitis ( EEE) during 1995-2015.2, analyzes the overall development, patent technology life circle, research area, cooperation and competition among countries/districts, basic information of institutes or outstanding individuals.The characteristics of various visual soft-wares are showed, the libraries should master data mining and information visualization technology, so as to provide consulting service to satisfy the deep level and personalized demands of users.

Objective To explore different aspects of empathy in patients with idiopathic generalized epilepsy and to study the effect of epileptiform discharges from different areas of the brain on empathy.Methods One hundred and fifty healthy controls and 62 patients with idiopathic generalized epilepsy were administered with a neuropsychological battery for basic cognitive assessment and an empathy scale after 24-hour electroencephalography monitoring.Results Compared with healthy controls,patients with epilepsy obtained significantly lower total scores and the cognitive empathy scores including perspectivetaking and fantasy subscale of the Interpersonal Reactivity Index-China (46.39 ± 9.74 vs 50.99 ± 9.97,t =-2.893,P=0.004; 23.31 ±7.10 vs 27.24 ±6.22,t =-3.974,P =0.000; 10.18 ±4.21 vs 11.84 ± 3.67,t =-2.838,P =0.005 ; 13.13 ± 4.46 vs 15.40 ± 3.84,t =-3.698,P =0.000,respectively).In contrast,the individuals with epilepsy did not score significantly different on the affective empathy,empathic concern and personal distress (P ＞ 0.05,respectively).Patients with frontal epileptiform discharges suffered the most on the total empathy scores,cognitive empathy and perspective-taking subscale when compared with other three groups of individuals (P ＜0.05,respectively),whereas the groups did not differ from each other in affective empathy,empathic concern and personal distress (P ＞0.05,respectively).No correlation was found between the empathy ability and other cognitive neuropsychological tests.Conclusions Patients with idiopathic generalized epilepsy is not associated with a general empathy deficit,but rather with a dissociated pattern combining impaired cognitive empathy and preserved affective one,which leads to a double-dissociation,supports the notion that affective and cognitive empathies are two distinct abilities.The activation of epileptiform discharges from the frontal lobe is a key factor that could diminish the empathy ability.

Radiomics is a new area of research, which converts imaging data into high?resolution quantitative imaging features by applying the automatic high?throughput imaging?feature?extraction algorithm. With the development of data science, more and more attention has been paid to the non?invasive and quantitative method in precision radiotherapy all over the world. This paper will briefly introduce the concept of radiomics and its application in precision radiotherapy.

In order to have a better understanding of the role of medical library in medical information service during the implementation of Healthy China strategy,the need of health information service of the public and medical scientific researchers in implementation of Healthy China strategy were analyzed by outlining the development history and major targets of Healthy China strategy,and how to meet the requirements of the development of Healthy China for medical library was studies,namely by improving its resources development,service patterns and staff construction according to the present situation of big data development,the challenges medical library is faced in users needs,resources,platform,space,professionals and funds,and the opportunities brought about by the expanding requirements,improving information academic level,advancing new technologies,favorable policies and environments with relevant suggestions put forward.

Objective:To explore the relationship between spino-pelvic sagittal and coronal parameters in Lenke 1 group of adolescent idiopathic scoliosis (AIS).Methods:The subjects were retrospectively col-lected from 2005 to 2013.On the posteroanterior and lateral radiographs, apical vertebra ( AV) , Cobb an-gle of main thoracic curve (MT), pelvic incidence (PI), C7 translation ratio (C7TR) and other sagittal parameters were measured and recorded.Comparison and correlation studies were conducted between these parameters using specific softwares.Results: In the study, 51 subjects, including 18 males and 33 fe-males, were recruited, aged (14.9 ±2.0) years averagely.The apical vertebra ranged from T7 to T11,with mean MT being 49.6闭±16.7闭, and mean PI 44.7°±6.7°.Significant correlation existed between PI and PT, SS, LL, as well as between LL and SS, TK ( P <0.05) .Significant differences were found in TK, LL and SS among the different LM groups, but no difference in the other sagittal parameters.AV had no significant correlation with any sagittal parameter.MT was significantly correlated with TK, LL and SS, but its correlation with PI was not significant.Conclusion:Most of sagittal parameters were significantly corre-lated in Lenke 1 adolescent idiopathic scoliosis, forming a regulation chain of spine-pelvic sagittal balance on the basis of PI.Significant correlation exists between some sagittal and coronal parameters.

Objective To understand the capacity of application,and discuss the types as well as the mechanism of these dysfunctions.Methods A battery of neuropsychological tests including tool naming,tool naming by function,using of transitive tools,novel task test and naming photographs (living and inanimate) were applied in this study.20 AD patients and 20 healthy controls were enrolled in the study.Results The AD patients performed worse than the controls on the tool naming,tool naming by function,application of transitive tool,novel task test,naming tasks of living and inanimate pictures.The results represented significance in all of the tests (t =-6.54,-5.94,-4.16,-4.81,-2.17,-2.08 ; P ＜ 0.05).There were significant correlations between the performances in application the tasks and the ADAS-cog,MMSE and ADL scores (P ＜ 0.05).Conclusion The findings indicate that AD patients have apraxia,mainly impairment in ideomotor apraxia and ideational apraxia.Additionally,the patients have significantly decreased performance in ideational apraxia.The result suggests that AD patients' apraxia might result from the semantic processing disorder.

Objective To investigate the effects of acupuncture at bilateral ST36 (Zusanli) on attention networks in healthy subjects.Methods The attention network test was used to compare the effects of after acupuncture at ST36 with the effects of before acupuncture on the efficiency of three anatomically defined attention networks:alerting,orienting,and executive control in 40 health university students.Results The alerting network effect was significantly higher (t=4.125,P＜0.001) after acupuncture ((45.60±3.49) ms) than before acupuncture ((33.20±2.88) ms).The executive control network efficiency was significantly higher (t=2.638,P＜0.05) after acupuncture ((87.97±4.21) ms) than before acupuncture ((97.67±4.66) ms).The orienting network efficiency was higher after acupuncture than before acupuncture,but there was no significant difference (P＞0.05).The average reaction time was significantly lower (t=4.848,P＜0.001) after acupuncture ((559.13 ± 10.66) ms) than before acupuncture ((590.57±12.80) ms).Conclusions These results suggest that there are selective enhancements of the alerting and executive control networks after acupuncture,while the orienting network is spared.

The current situation of medical information was analyzed by displaying the co-appearance of countries and time, top 5 journals and co-appearance of subject headings in papers on medical information published in 1995-2014 with the papers on medical informatics covered in ISI Web of Science Database as an sample , in order to promote the study and provide reference for the related persons and institutions .

In order to show the development situation and trend in plaque research, Thomson Innovation Platform-covered application of patents associated with plaque researches was quantitatively analyzed using the Thomson Data Analyzer and Thomson Innovation or other tools, which revealed the overall development situation, the main accepted countries, the main application institutions and the technological direction layout of patents associated with plaque researches.

After a description of the background of hierarchical diagnosis and treatment in China, the total frame-work of hierarchical diagnosis and treatment system in the Internet+era was proposed by analyzing its needs in the Internet+ era, and the main functions of its data center, information system, clinical professional collaboration and public health service were elaborated in order to promote medical health actions and construction of hierarchical diagnosis and treatment system in China.