1.Advances in the study of molecular identification technology of Echinococcus species
Zhang, R.J. ; Li, J.Z. ; Pang, H.S. ; Luo, Z.H. ; Zhang, T. ; Mo, X.J. ; Yang, S.J. ; Cai, Y.C. ; Lu, Y. ; Chu, Y.H. ; Song, P. ; Chen, M.X. ; Ai, L. ; Chen, J.X.
Tropical Biomedicine 2022;39(No.3):434-443
The larvae of Echinococcus (hydatidcyst) can parasitize humans and animals, causing a serious zoonotic
disease-echinococcosis. The life history of Echinococcus is complicated, and as the disease progresses
slowly after infection, early diagnosis is difficult to establish. Due to the limitations of imaging and
immunological diagnosis in this respect, domestic and foreign scholars have established a variety of
molecular detection techniques for the pathogen Echinococcus over recent years, mainly including nested
polymerase chain reaction (PCR), multiplex PCR, real-time quantitative PCR, and nucleic acid isothermal
amplification technology. In this article, the research progress of molecular detection technology for
Echinococcus infection currently was reviewed and the significance of these methods in the detection
and diagnosis of hydatid and hydatid diseases was also discussed.