Colorectal cancer is a common malignancy in the digestive tract,open and laparoscopic surgery are the main treatment methods.Anastomotic fistula,anastomotic bleeding,ileus,voiding and sexual dysfunction are the common postoperative complications.Chylous fistula,incision infection,pulmonary infection and incision metastasis occasionally occurred.Compared with open surgery,laparoscopic surgery does not increase the postoperative complications,and it can be safely applied in the radical resection of colorectal cancer.

Objective To compare two surgical methods of ectopic pregnancy between laparoscopic and laparotomy and evaluate therapeutic effect. Methods The clinical data of ectopic pregnancy patients who underwent from laparoscopic(65 cases) and open surgery(54 cases) were retrospectively analyzed,the data such as total blood loss,postoperative demulcent effect, the anus exhausting time, postoperative complications, duration of hospitalization, fever,and duration of antibiotics, abdominal scar, indwelling catheter time were analyzed between these groups. Results There were significant differences on total blood loss[(37.5 ± 15.6)ml vs (21.3 ± 9.5)ml], postoperative demulcent effect(82% vs 26%), the anus exhausting time [(32. 6 ± 7.8) h vs (19.4 ± 4. 2) h], postoperative complications (46% vs 17%) ,duration of hospitalization[(7.6 ± 1.9) d vs(3.3 ± 1.1) d] ,fever(74% vs 24%), and duration of antibiotics [(6.3 ± 2.2) h vs (3.6 ± 1.2) h], abdominal scar (with vs without), indwelling catheter time [(29.5 ±4. 6) h vs(7.4 ± 2.3) h] between laparotomy and laparoscopic groups (P ＜ 0. 05). Conclusion Laparoscopic surgical treatment of ectopic pregnancy was superior to the traditional open group.

Cascade in cerebral ischemic injury may cause cholinergic dysfunction,inflammation and oxidative stress. It plays an important role in the pathological processes of vascular dementia. A large amount of basic research has confirmed that cholinesterase inhibitor and N-methyl-d-aspartate receptor inhibitor may improve cognitive function in patients with vascular dementia. However, the efficacy of these drugs has been confirmed in only a part of the patients, and their safety and efficiency have not achieved the expected results. Thus, it needs further study and exploration.

Objective To investigate the incidence, cause,prevention and treatment of early postoperative inflammatory intestinal obstruction(EPIIO)in patients undergoing laparoscopic and open radical resection of colorectal cancer. Methods From September 2000 to September 2006,483 cases of colorectal cancer were divided into two groups according the procedures received: laparoscopic surgery(232 cases)and open surgery(251 cases).The incidence of early postoperative intestinal obstruction was compared between the two groups. Results 1.In laparoscopic group,14 cases(5.69%,14/246)were converted to open surgery;2.The incidences of EPIIO in LS and OS group were respectively 3.02%(7/232)and 7.97%(20/251)(P＜0.05,x2=5.60＝.In LS group,6 EPIIO caseswere cured conservatively, one underwent surgery, while in open surgery group,18 cases recovered conservatively, two received surgery. Conclusions 1.Significantly less cases suffered from EPIIO in laparoscopic group.2.Most EPIIO cases will recover conservatively, in cases with repeated symptoms or when strangulation of bowel is suspected open surgery should be attempted.

Objective To investigate the discussion of risk factors of severe head injury with multiple organ dysfunction syndrome.Methods The clinical data of 149 cases with severe traumatic brain injury patients were retro-spectively analyzed,and the risk factors in patients with severe traumatic brain injury were collected,which may affect MODS,such as gender,age,GCS score,associated injuries,chronic underlying diseases,infections and other details, statistically analyzed were combined with incidence of MODS.Results (1 )Univariate analysis results could be seen, age,chronic underlying diseases,admission GCS score,extensive brain parenchymal damage,merge large organ dam-age,brain herniation,concurrent infection,massive blood transfusion were risk factors of MODS severe traumatic brain injury(χ2 =12.962,11.725,11.021,13.894,11.486,12.031,12.967,13.078,P=0.023,0.025,0.027,0.017, 0.023,0.018,0.021,0.019).(2)MODS rate and the number of risk factors were positive correlation(r=0.528,P=0.021).(3)With the increase of the number of mortality in patients with MODS organ dysfunction occurred signifi-cantly increased,MODS patients in this group,the two organs mortality was 17.4%,the three organs were 46.7%, four or more mortality was 87.5%(χ2 =11.735,13.933,12.748,P=0.028,0.019,0.025).Conclusion Age, chronic underlying diseases,GCS low,extensive parenchymal injury,combined injury,the occurrence of hernia,com-plicated by infection,massive blood transfusion were independent risk factors for brain injury,which should be payed attention.

OBJECTIVE:To observe the distribution of fluorescent material in the respiratory tract of animals with the use of small animal imaging technology to quickly evaluate the effects of respiratory drug delivery. METHODS: The Kunming mice in the experimental group were administered with Cy5.5 fluorescent-labeled aerosol,meanwhile,a positive control group was set up by injecting same amount of compound anhydrous diethyl ether solution via tracheal incubation,with negative control group inhaled the same amount of non-Cy5.5 fluorescently-labeled aerosol. The fluorescent distribution of the aerosolized particles in the respiratory tract was observed. RESULTS: Fluorescently-labeled aerosol was observed in both the experimental group and the positive control group but not in negative control group. CONCLUSION: The small animal imaging technology is expected to be used as a rapid and effective method for evaluating the efficacy of respiratory drug delivery.

MinK-related peptides is a unique family of ion channel ancillary subunits,that modify voltage-gating,conductance and pharmacology of ion channel subunits.This article reviews MinK-related peptides on the gene and protein structure,subunits from a variety of subfamilies,and the potential role in physiology and pathology.

98%. Conclusion The developed method is simple, reproducible and easy to operate. The solvent is cheap, with low boiling point and easy to recovery property.

Objective: To establish the assay method of 2,3,5,4′-tetrahydroxystilbene-2-O-?-D-glucoside in Jiangzhitongmai Tablet (Radix Polygoni Multiflori, Rhizoma Alismatis, etc.). Methods:HPLC conditions were as fellows: Chromasil C 18 column, a mobile phase of CH 3CN-H 2O(25∶75), and the wavelength at 320nm. Results:2,3,5,4′-tetrahydroxystilbene-2-O-?-D-glucoside was linear within the range of 0.044～ 0.7 ?g with a correlation coefficient of 0.9999. The average recovery was 98.54%. Conclusion:The method is simple, swift, accurate and practical in quality control of Jiangzhitongmai Tablet.

Objective:To study the relationship between body image and s ubjective happiness Method:225 female students of a normal scho ol in Nanchang were tested with self-designed self-image scale, the index of the ir body (height, weight ) were also collected Results:In 5 8 6% of our sample, there was a obvious difference between the self-judgement of sel f-image and the result of body index, 11 4% had disturbance of body image Bet we en those with disturbance and those without, there were significant differences in desire to be slim, fitness of self, and ideal body image There was signific a nt correlation between satisfaction of fitness of oneself and subjective happine ss, between self-induced vomiting and using drugs in fitness Conclusion : Girls with disturbance