Background: The purpose of this study is to evaluate serum creatinine as a marker of estimated glomerular filtration rate (eGFR) in alcohol use disorder people, and to determine correlation between mean arterial pressure (MAP) and eGFR in chronic kidney disease classification level. Methods: In this study, 99 people were examined between January 2024 to November 2024. We measured serum creatinine based GFR using the Cockroft Gault formula. Results were analyzed SPSS. Result: The mean subject age was 48.2±9.9 years, male: female ratio was 5:1. Mean arterial pressure was 103±13.5 mmHg, eGFR 95.5±28.8 ml/min/1.73m2, and mean arterial pressure was significantly correlated with estimated glomerular filtration rate (P<0.05) and no difference between male and female recipients. Conclusion According to our research, one of the optimal methods for assessing kidney function is the creatinine-based CKD calculation method, and excessive alcohol consumption is a risk factor for chronic kidney disease, as well as one of the main causes of complication and mortality in cardiovascular disease.

Objective: In this study it was aimed to demonstrate the hypolipidemic and hypoglycemic potentials of Agrypum extract on alloxan-induced diabetic rats. Materials and methods: Eighteen male Wistar rats of weights between 140 g were used for the study and divided into three groups of six rats each. The rats of the non-diabetic control group were given 1 ml of distilled water daily. Two other groups induced with diabetes using alloxan by a single dose administration of 120 mg/kg body weight (BW); one of these diabetic rat groups were treated with seeds of this plant (Agrypum) extract daily at 1.5 ml/100 g BW for 4 weeks while the other group was left untreated. Blood samples were collected and total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL), lowdensity lipoprotein (LDL) and glucose levels were assayed. Results: After four weeks of treatment, data indicated significant reductions in BW, blood glucose, TG, TC and LDL levels of diabetic rats treated with seeds of this plant (Agrypum) extract compared to the non-treated group. The treated diabetic rats also indicated significantly higher HDL levels compared to the non-treated group. Conclusion: Treatment of diabetic rats with the seeds of this plant (Agrypum) extract lowered blood glucose, TG, TC and LDL levels and increased the HDL level. This shows that the extract has both hypoglycemic and hypolipidemic effects.