1.A Case of Mitral Valve Re-replacement Combined with Idiopathic Thrombocytopenic Purpura.
Hideo YOSHIDA ; Kenji SANGAWA ; Yutaka SAKAKIBARA ; Kohtaroh SUEHIRO ; Masahiro OKADA ; Takeshi SHICHIJOH ; Osamu OHBA
Japanese Journal of Cardiovascular Surgery 1993;22(4):372-375
Cardiac surgery associated with idiopathic thrombocytopenic purpura (ITP) is rare, and only 10 cases have been reported in the literature. In this report, we described the successful surgical management of a patient with ITP, diabetes mellitus and malfunction of mitral bioprosthetic valve. A 62-year-old male, who underwent mitral valve replacement (MVR) by means of a Carpentier-Edwards valve prosthesis and CABG ten years ago, developed malfunction of mitral prosthetic valve. The preoperative platelet count was 52, 000/mm3 and PA-IgG elevated markedly. The diagnosis of ITP was based on findings of bone marrow examinations. Thrombocytopenia was treated by steroids for 4 weeks and large dose γ-globulin (20g/day) for 5 days preoperatively, but platelet count did not increase. Platelet rich plasma (PRP) was transfused prior to cardiopulmonary bypass (CPB) and fresh blood was added to the priming material of CPB. Re-MVR was performed by means of mechanical valve prosthesis. After operation, large doses of γ-globulin and transfusion of PRP were performed for 3 days, and the postoperative course was uneventful. Other reports in addition to this study reveal that cases of cardiac surgery associated with ITP should be initially controlled preoperatively with steroids or high-dose γ-globulin, and if these treatments are harmful or ineffective, splenectomy should be considered.
2.The Attempt to Develop a "Model Program" on the Basis of the Objectives Established by the Ministry of Health, Labour and Welfare in the New Postgraduate Clinical Training System
Kazuhiko KIKAWA ; Masahiro TANABE ; Kiyoshi KITAMURA ; Hayato KUSAKA ; Masamune SHIMO ; Katsusada TAKAHASHI ; Yujiro TANAKA ; Tadashi MATSUMURA ; Takao MORITA ; Kunihiko MATSUI ; Takashi OHBA ; Hirotsugu KOHROGI ; Osamu SHIMODA ; Taichi TAKEDA ; Junichi TANIGUCHI ; Tatsuya TSUJI ; Hiroyuki HATA
Medical Education 2006;37(6):367-375
Clinical training programs play an extremely important role in the new postgraduate clinical training system introduced in 2004 because facilities for clinical training now include various health-related institutions in addition to the university hospitals and special hospitals for clinical training used in the previous system. Although educational goals have been established by the Ministry of Health, Labour and Welfare, trainees may have difficulty achieving these goals, even under the guidance of staff at the various facilities. There are differences in the function and quality of health-related institutions in the community. For the practical and convenient application of educational goals, we have attempted develop a “model program” to supplement the objectives indicated by the learning goals with more specific objectives. These supplementary objectives can be modified by individual institutions. We hope that this “model program” contributes to the development of objectives for each institution and helps improve the quality of the postgraduate training system in Japan.