1.Natural Childbirth in a Woman with Thrombotic Collagen Disease on Medication with Low Molecular Weight Heparin and Aspirin for Pregnancy-induced Hypertension
Mitsuya ONO ; Ryuichi SADA ; Hisanori KOBARA ; Osamu OGUCHI ; Ikuko NAKAI
Journal of the Japanese Association of Rural Medicine 2008;57(4):647-649
The Patient was a 30-year-old woman. Four years previously, the woman had undergone ileectomy for thrombotic ileal erosion. After being discharged, she received regular medical treatment for thrombotic renal hypertension at our Department of Internal Medicine, and eventually her case was diagnosed as a collagen disease. She was dosed up with depressors and aspirins. Two years later, she got married. Next year, she became pregnant, but miscarried. A causal link between collagen disease and miscarriage was suspected. In the same year, she became pregnant for the second time. The administration of low molecular weight heparins was initiated in addtion to doses of aspirin. In the last trimester of pregnancy (In the latter half of pregnancy?), pregnancy-induced hypertension developed. The woman was immediately hospitalized and placed at bed rest. The dose of low molecular weight heparin was increased. She gave birth to a healthy child. This experience taught us that working in closer collaboration between doctors of internal medicine and obstetricians is of vital importance for the health and safety of pregnant women with a collagen disease and successful childbirth.
Pregnancy
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Human Females
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Heparin, Low-Molecular-Weight
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Collagen
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Aspirin