1. A COMPARATIVE STUDY OF ALCOHOL-DEPENDENT PASIENTS PERSONALITY AND ANXIETY LEVEL
Gantulga G ; Khishigsuren Z ; Odongerel ; Bertsetseg G
Innovation 2015;9(1):82-85
Russian physiologist I.P.Pavlov theorized that there are four fundamental personality types, choleric, sanguine, phlegmatic and melancholic. These four temperaments have been currently recognized as the basis of disease prevention, diagnosis and treatment in the medical field. The melancholic temperament has known as the most popular temperament according to current studies This study was conducted by descriptive- cross sectional design. We used a guestionnaire, contained Eysenck and by Spielberg-Hanin tests. In total, 83 inpatient males of the addictological clinic of NCMH. All ethics considered. In our study, were participated alcoholic patients, aged 24 -61 years, with II and III stages ofalcoholism. By the Eysenck Personality test, most of total of patients (43%) were melancholic, with statistical significant (р=0. 04). But it no statistical correlation for stage of alcoholism (p=0.31). The anxiety level was significantly higher in melancholic patients by Spielberg-Hanin test and Zung test. This result maintained statistically that there is a direct relevance betweenmelancholic temperament and anxiety. The most of alcohol-dependent patients had melancholic temperament. Although, there is no correlation to stages of alcoholism. The anxiety level evaluated by Spielberg and Zung’s test. Testsdetermined relatively higher anxiety in melancholic patients compared to other temperaments.
2.The result of the assessing delusion symptoms in alcohol related psychosis
Odongerel S ; Gantsetseg T ; Khishigsuren Z ; Davaakhuu ; Dolgormaa M
Mongolian Medical Sciences 2013;165(3):50-53
Background. Acute alcohol delusions of persecution usually show up delusions of persecution, which is begun auditory hallucination, illusion, fair, anxiety in night time. The patient may conduct to attempt suicide or social harmful activities from the fair and the anxiety. Therefore, we studied types of delusion in alcohol related psychosis and risks of social harmful activities due to delusion. Aim. To identify types of delusion in alcohol related psychosis, risks of social harmful activities due to delusion.Materials and Methods. The study was conducted on the 110 cases of suicide (100 cases among males and 10 cases among females). In the study used special questionnaire with 45 chapters and 431 questions. The current mental condition was identified by the objective and subjective history of patients with Michigan scale questionnaire.Results. We were compared forms of alcohol related psychosis to delusion symptoms, there were occurred 29.6% of 64 patients with delusions of persecution during withdrawal state with delirium without convulsions (F10.40) and 34.4% of 64 patients with delusions of persecution during predominantly delusional psychotic disorder (F10.52). Those patients in 37 case (or 33.6%) were with suicidal thinking and 20 patients (or 18.2%) made suicidal attempts. 23.4% of 64 patients with delusions of persecution, 24.07% of 54 patients with hallucinatory delirium made suicidal attempts.Conclusions. Delusion symptoms in alcohol related psychosis are belonged to clinical form and were showed up many types.
3. DIAGNOSTIC TREATMENT SITUATION OF BIPOLAR DISORDER
Gantsetseg T ; Khishigsuren Z ; Odongerel S ; Minjmaa R ; Nyamtsetseg J ; Sarantsetseg T ; Sugarmaa SH ; Gantulga J ; Tuya N
Innovation 2015;9(1):28-33
WHO informed that across world an average of 565 young people aged 10 to 29 die every day through interpersonal violence. Some studies mentioned that anxiety was most frequently occurred as one of the psychological onsequences among victims of child abuse. Recent research on effects of adverse early life experiences on central nervous system as stress systems (hypothalamus-pituitary-adrenal axis-HPA) has provided a greater understanding of the link between childhood abuse and susceptibility to anxiety disorder. Therefore, this research was done to study anxiety among abused adolescents, some physical parameters and level of cortisol in saliva.Total number of participants were 149 children aged between 11-16 years (number cases were 53, matched control subjects were 96). The Spence Children’s Anxiety Scale (SCAS; Spence, 1997) is a 38-item self-report uestionnaire that assesses multiple symptoms of childhood anxiety isorders based on current diagnostic criteria. All participants were measured the cortisol in the saliva by Cortisol ELISA kit, Sigma, USA. Average age of all subjects in the study was 13.52±1.57 and 102 of all subjects were female and 47 were male. All anxiety symptoms of case group was statistically significance higher (p<0.01) than control group. The average amount of salivary cortisol of case group was (21.3±8.1 ng/ml) statistically significantly lower (p<0.01) than average amount of control group (31.56±16.9 ng/ml). Anxiety was more frequently occurred among abused children and blunted cortisol responses might indicate a level of impaired HPA functioning that could constitute a vulnerability to psychopathology with exposure to anxiety.
4.To evalate the effect of “Vitos” shilajit shot preparation on rat femur fracture using X-ray
Batchimeg B ; Davaasambuu T ; Badamtsetseg S ; Bayanmunkh A ; Tsetsegmaa S ; Odongerel A ; Lkhagva L ; Khurelbaatar L
Mongolian Pharmacy and Pharmacology 2021;19(2):13-21
Introduction:
Shilajit and Rhodiola Rosa L are widely used in Mongolian Traditional medicine for the management of diseases and for fracture healing. The aim of this study was to evaluate the pharmacology effects of the “Vitos” Shilajit Shot preparation on fracture healing and callus stages in rats by X-ray.
Material and methods:
We used non-liner Wistar rats for in vivo experiments, there are sixteen rats were randomly grouped as a positive control, negative control, “Vitos” Shilajit shot experimental and standard groups. The positive group was as healthy animals and other groups were created femoral fracture by Bonnaren’s device. Then negative control group was oral administered distilled water, whereas 4.1ml/kg of “Vitos’ Shilajit shot administrated via oral gavage to experimental group through 56 days. X-rays were performed to assess fracture healing effects within 14, 28, 42, 56 days and callus stages.
Results:
Significantly higher callus volume and callus staging were observed in the “Vitos” Shilajit shot group compared with the negative control and standard groups. Also “Vitos” Shilajit shot group was becoming as bridging between both end of fractures and get hard callus formulation ready observation of X-Ray radiograph on 4 weeks post fracture. The fracture healing process was slightly reached to callus remodulation such as final stage of bone formulation on 56th day.
Conclusion
The results of this study reveal that, “Vitos’ shot preparation, which contains an extract of Rhodiola Rosa L and thick extract of Shijilat has a treatment effect and enhancing and supporting callus of bone fracture healing.
5.Effect of “shilajit+golden rosa” or vitos preparation on immune response cells (CD4, CD8, IGG, CD64) by azathioprine induced immunosuppression in mice
Batchimeg B ; Davaasambuu T ; Badamtsetseg S ; Bayanmunkh A ; Odongerel A ; Tsetsegmaa S ; Choijamts G ; Lkhagva L ; Khurelbaatar L
Mongolian Pharmacy and Pharmacology 2022;20(1):39-44
Introduction:
During many decides, compounds derived from natural raw materials have demonstrated their effectiveness as therapeutic agents in different areas, such as metabolic disorder, immune system diseases and its regulations. Natural based products, like herbal medicines and minerals are implicated in the regulation of immune function. They control the immune system in a pleiotropic manner and participate in various processes of the adaptive/innate immunity. Therefore, natural raw material has great potential for targeted immune modulators, in the treatment of certain types of immunologic and inflammatory diseases, like rheumatoid arthritis, plaque psoriasis, ankylosing spondylitis and immune deficiency. The purpose of this survey was to study influence of “Shilajit +Golden Rosa” combined shot preparation named by Vitos on immune system in the experimental and preclinical circumstances.
Goal:
The purpose of this survey was to study influence of “Shilajit +Golden Rosa” Vitos shot preparation
on immune system in the experimental and preclinical circumstances.
Material and Methods:
The immune deficiency was to created by Azathioprine through 5 days in the Balb/c mice after that control group, preparation of “Shilajit +Golden Rosa” Vitos shot were administrated appropriate doses by oral during 10 days. Then we collected blood and quantified amount of CD4+, CD8+, IgG and CD64 (Mouse Elisa Kit Assay: Catalog.No:WAM-568, Elisa Reader, 450 нм, Melsin Medical Co.LTD, www. melsin.com) on the 5th, 10th days.
Results:
All statistical analyses were conducted with SPSS version 20.0 software (IBM, Armonk, NY). Oneway ANOVA was used to assess statistical significance between “Shilajit +Golden Rosa” Vitos shot group and days of observation. Mean values of CD4+, CD8+, CD4/CD8 ratio, IgG, CD64 levels determined in the control and sample group. CD4+, CD8+, CD4/CD8 ratio, IgG and CD64 levels were significantly increased in the “Shilajit +Golden Rosa” Vitos shot group compared with control group by 20.8-67.8 per cent (p<0.05, p<0.01).
Conclusion
It’s concluded that, “Shilajit +Golden Rosa” Vitos shot preparation shows immune-stimulator activity not only in the level of cellular (T cells:CD4+, CD8+) but also humoral immunity (B cells: IgG, CD64) in the previously using Azathioprine (75mg/kg) to provoke pathological model of immunosuppression