Background: Development and progression of cancer is accompanied by different morphological and functional changes of cells. One of the most important changes is the expression and activity of enzymes in the cellular fatty acids metabolism that reflects in cell membrane lipid composition and increases fluidity of cancer cell membrane. The Ellipin, prepared from bovine liver, is a newly developed anticancer agent containing several important fatty acids.Goal: To investigate effects of Ellipin on hepatic cancer cell function such as proliferation, migration and adherent activity and apoptosis of cancer cell lines in vitro.Materials and Methods: This study was conducted in the Laboratory of Molecular Biology, Institute of Biology, MAS. The Ellipin was developed in the Drug Research Institute of Monos group. HepG2, HCC, 23132/87, MDCK cells lines and the primary liver cancer cells (PCC) were used for proliferation assay. Only HepG2 cell line was used for MTT, Migration, Spreading and Apoptosis assays.Results: The results of proliferation assay showed that the ellipin decreased the proliferation activity of HepG2 and PCC cells depending on concentrations; in 50μg/ml 2-3 times, 250μg/ml fully stopped cells divisions. The Ellipin reduced mitochondrial reeducates enzyme activity of HepG2 cells depending on its concentrations. For example, in 50μg/ml ellipin concentration case, the number of alive cells decreased 2 times. The migration of HepG2 cells treated with 100μg/ml ellipin was decreased by 22.3% compared to the control cells. Also the number of adhered cells was reduced by Ellipin treatment. After 50μg/ml, 100μg/ml, 250μg/ml ellipin treatment, the number of apoptic cells were 14,6%, 45,6%, 100% of initial culture cells, respectively.Conclusions: Our results showed that the Ellipin suppresses HepG2 cancer cell proliferation and decreases migration and spreading activities and also inducts the cell apoptosis.

Background: Anemia is still being a population’s challenging issue regardless of high development of countries around the world. According to a study regarding prevalence and etiology of anemia conducted in 187 countries around the world, the anemia rate is 23 176 per 100 000 population. In accordance with the “5th National Nutrition Survey” study conducted in our country in 2017, one of every five women (21.4%), aged 15-49 years, 16.2% of reproductive age women and 3.0% of men are anemic. The current study was conducted due to it is still essential to study and identify the etiology of anemia, determine its prevalence, plan appropriate intervention, and organize future preventive measures, depending on the socio-economic conditions, location, diet, and customs of the Mongolians. Aim: To identify anemia among the adult population, determine the type and severity of anemia. Materials and Methods: The cross sectional study was conducted during between May 2022 and Sep 2023 and adults aged above 18 years were included. Moreover, we identified anemia cases based on the laboratory test results and determined the anemia severity grade. Statistical analysis was performed by using SPSS software. Results: Among the participants, 6.7% of them, 9.9% of females and 2.8% of males are anemic. Prevalence of mild, moderate and severe anemia is 66.7%, 30% and 3.3%, respectively. While the prevalence of anemia among reproductive age women is higher, the prevalence of anemia increases with age. The anemia prevalence in Ulaanbaatar region, Western region, Khangai mountainous region, Central region and Eastern region is 583 (25.6%); 171 (7.5%); 343 (15.1%); 921 (40.4%); and 261 (11.4%), respectively. By regional location, the prevalence is high in the Central region, with varying prevalence in other regions. Conclusion Anemia was detected in 6.7% of the total study population, 9.9% of females, and 2.8% of males were anemic. Of those with anemia, 66.7% had mild anemia, 30% had moderate anemia, and 3.3% had severe anemia. Moderate and severe anemia were more common in females than in males.

Introduction: 16% of the world's 8 billion people, or more than 1.3 billion, are people with special needs or people with disabilities. Of these, there are unofficial studies that show that there are about 650 million people with disabilities in Asian countries. [1] One of the most common problems faced by people with special needs is that disability service organizations, especially pharmacies, do not have access to complete information on their necessary medications.
According to the 2019 data of the National Statistics Committee [4] in our country, 3.4 percent of the total population or 107.6 thousand are citizens with special needs. Article 1.1 of the Law "On the Rights of Persons with Disabilities" [5] provides for the equal rights of persons with disabilities to participate in social relations, to ensure and implement them, to provide an accessible environment, to create conditions, housing, public buildings, roads, public transport, and information., communication technology is included as being accessible to people with disabilities. However, health and pharmacy services for people with special needs are very challenging.
The main basis of this research work is to make pharmacy services easier for people with special needs, especially people with speech, hearing, visual, mental, and motor disabilities, and to identify and solve problems. Methods: The research was carried out in a one-moment model. Based on the General Department of Development of People with Disabilities, data was collected by questionnaire using the minimum sample size calculation, which was calculated as 478 people per 1000 population. Statistical analysis was carried out using SPSS-23 software.
Our survey was conducted between November to December 1, 2022 using a snapshot model. Processing of results was carried out using survey data processing. Conclusion
1. According to the 2019 data of the National Statistics Committee, 3.4 percent or 107.6 thousand of the total population of our country are citizens with special needs. This information has not been updated for 2021-2022.
Out of a total of 478 people in the survey, 54% were male, while 42.8% of the respondents were 20-30 years old. 48.8% of citizens use pharmacies independently, 42.4% with the help of a guardian, and 8.8% of other citizens use pharmacies. The lack of understanding of drug information on prescription forms affects the physician's prescription, drug information, visual and hearing impairments, and misunderstandings.
2. People with speech, hearing, visual, mental, and motor disabilities face the biggest problem in using the pharmacy. Therefore, it is a priority to make certain innovative changes in order to make pharmacy operation* equal to citizens. These include: Prescription forms can be read using technology such as Qr and AR on the phone, delivering medication instructions and information in audio form to people with visual and mental disabilities, providing more clear and understandable information to people with speech and hearing disabilities identifying medications for people with visual impairments, and using drugs correctly. We believe that suggestions and solutions are needed, such as placing names and instructions in braille on product labeling and packaging, implementing stairs and doors for people in wheelchairs or with mobility impairments in accordance with standards in all buildings, and providing seats for stairwells between floors. In most cases, it takes 10-20 minutes for people with disabilities to visit a pharmacy. Some citizens are experiencing delays in services for up to an hour. It can be seen that spending a lot of time to visit a pharmacy is difficult for citizens.
In order to solve this problem, under the supervision of a manager and a pharmacist, a post-graduate student of "Pharmacy" of the "University of Pharmaceutical Sciences" should be created to provide advice and information to citizens and reduce the burden.