No abstract available.
Ocular Hypertension*

Perimetric tests were performed in 32 ocular hypertensive eyes(17 patients) with the C 30-2 threshold STATPAC program of the Humphrey Visual Field Analyzer. The global indices of 32 ocular hypertensive eyes were compared with those of 34 normal eyes(17 controls). None of 34 normal eyes had visual field sensitivity loss. However, 3 of 32 ocular hypertensive eyes, which was 9.4%, had visual field sensitivity loss beyond the 95% normal confidence limits. Of these 3 eyes, 2 eyes(1 patient) showed paracentral scotomas(CPSD, P<5%), and 1 eye showed generalized depression(MD, P<5%).
Ocular Hypertension* ; Visual Fields*

14 patients with the ocular burn/223 patients with burn in which male: 8, female: 6 children: 3 adult: 11, burn with the hypertention: 6.2%. The results have shown that. The results: the ocular burn should be immediately cleaned with NaCl 0.9% within 30 minutes, it is contraindicated for use of antagonist because of the more burn. The ocular hypertension found in the moderate and severe burns. It is difficult to evaluate. The treatment required the combination of theinternal treatment and surgical treatment. The diagnosis of the ocular hypertension due to burn helps the conservation of the eyeball, keeps a functional part from which the photo surgery such as the aritificial corneal transplantation can be applied.
Ocular Hypertension ; Burns, Chemical

Objective: This study described the clinical profile of a four-generation Cebuano family with juvenile-onset open-angle glaucoma (JOAG). Methods: Thisis a case series conducted in the out-patient department of Cebu Velez General Hospital. Thirtyeight (38) members in a four-generation family from the northern part of Cebu province were investigated. General medical and ophthalmologic histories were taken. Complete ophthalmologic examination was done. Results: Forty-two (42%) percent of participants examined had increased intraocular pressures (IOP); 15 were diagnosed with JOAG, one had ocular hypertension. There were more females than males affected. Mean age when symptoms were first noted was 14.56 ±6.63 years and mean age at diagnosis was 16.3 ±7.84 years. The most common initial symptom was rainbow or halos around lights (87.5%). Mean refraction was -3.09 ±2.54 diopters for both eyes. Mean IOP on examination was 24.56 ± 20.17 mmHg. Gonioscopy showed open angles with flat iris plane. All affected participants underwent medical treatment and 69% needed surgical interventions. Conclusion This family demonstrated the typical JOAG phenotype consisting of early age of onset, strong family history with an autosomal dominant pattern of inheritance, myopia, open angles, and increased IOP refractory to medical treatment.
Glaucoma ; Ocular Hypertension ; Phenotype ; Pedigree

PURPOSE: To study the correlation between the Humphrey standard automated perimetry (SAP) and the Humphrey Matrix Frequency Doubling Technology (FDT) perimetry and diagnostic usefulness of the Humphrey Matrix FDT perimetry. METHODS: This study included 170 eyes of 170 patients. The 170 eyes were classified into 50 normal eyes, 20 ocular hypertensive eyes, 50 glaucoma-suspect eyes and 50 glaucomatous eyes. All subjects were examined with the Humphrey Matrix perimetry and the Humphrey standard automated perimetry. We studied the correlations between mean deviation (MD) and pattern standard deviation(PSD) of the Humphrey SAP and those of the Humphrey Matrix perimetry, respectively, in each of the classified group. RESULTS: Overall, MD and PSD of the Humphrey SAP were significantly correlated with MD and PSD of the Humphrey Matrix perimetry, respectively. However, MD and PSD of the Humphrey Matrix perimetry were not showed a significant correlation in normal subjects (P>0.05). CONCLUSIONS: In this study, there were significant correlations between the MD and PSD of the SAP and those of the Humphrey Matrix perimetry in glaucoma, glaucoma-suspect and ocular hypertension. These finding suggests the Humphrey Matrix perimetry has performance characteristics similar to SAP and diagnostic value.
Glaucoma ; Humans ; Ocular Hypertension ; Visual Field Tests*

A case, 25-year-old male student who is thought to have been suffered from glaucomatocyclitic crises in the left eye, is presented. Authors have followed this patient for about one and a half years. During the time, 10 times of recurrent unilateral attacks of ocular hypertension have been noted with assoicated mild iridocyclitis. An attempt was made to evaluate the clinical pictures and review the literatures.
Adult ; Humans ; Iridocyclitis ; Male ; Ocular Hypertension

PURPOSE: This study was undertaken to evaluate if the reduction of intraocular pressure (IOP) observed in a uniocular trial correlates with an IOP reduction observed in the fellow eye. METHODS: The study was performed on forty patients with bilateral glaucoma or suspect glaucoma who underwent a uniocular trial of 0.005% latanoprost and subsequently received the same drug in the fellow eye after 1 week. Inter-eye IOP variations were less than 3 mm Hg over two measurements, and were followed minimally for 4 weeks. The uniocular IOP reduction (IOP before medication - IOP after medication) and the net IOP reduction (IOP change in the trial eye after medication - IOP change in the fellow eye) were calculated. The uniocular IOP reduction and net IOP reduction in the trial eye was compared with the results from the fellow eye. RESULTS: The mean uniocular IOP reduction in the trial eye and the fellow eye were 3.6+/-2.42 mm Hg and 2.78+/-2.16 mm Hg, respectively (r=0.390, r2=0.152, P=0.013). The mean net IOP reduction in the trial eye and the opposing eye were 3.55+/-1.70 mm Hg and 3.15+/-1.83 mm Hg, respectively (r=0.782, r2=0.612, P=0.000). CONCLUSIONS: A uniocular drug trial in patients with similar IOPs between their eyes can adequately predict the IOP lowering effect of a medication.
Glaucoma* ; Humans ; Intraocular Pressure ; Ocular Hypertension

OBJECTIVE: Since cataract and glaucoma often coexist, and there is no agreement as to their optimal management, a review of the surgical strategies for coexisting I cataract and glaucoma is necessary. The latest evidence-based findings from various studies are presented. METHODS: A literature search of the latest full articles (up to September 2006) was conducted on the surgical management of coexisting cataract and glaucoma. The results of the 2001 Johns Hopkins milestone study were also included for analysis and comparison. RESULTS: Evidence is strong that trabeculectomy is associated with increased risk of postoperative cataract. Though cataract surgery alone may be appropriate for some glaucoma patients, combined cataract and glaucoma surgery lower long-term intraocular pressure (IOP) more than cataract extraction alone. Use of intraoperative mitomycin-C is beneficial in combined surgery. Limbu and fornix-based conjunctival flaps are equally effective for lowering IOP combined surgery. Trabeculectomy alone lowers long-term IOP more tha combined extracapsular cataract extraction (ECCE) and trabeculectomy. Evidence is weak that combined surgery with phacoemulsification rather than ECCE results in lower long-term IOP, as does two-site compared to single-site combined surgery. CONCLUSION: The literature does not point to an optimal strategy for controlling in patients with coexisting cataract and glaucoma needing surgery. There is a continued need for high-quality studies of longer duration and more information on the optic nerve and visual field.
GLAUCOMA ; CATARACT ; INTRAOCULAR PRESSURE ; OCULAR HYPERTENSION ; OCULAR HYPOTENSION ; SURGERY ; PHACOEMULSIFICATION ; TRABECULECTOMY

Peripapillary atrophy is more frequently seen and larger in glaucomatous eyes than in ocular hypertension or normal eyes. There have been numerous debates whether peripapillary atrophy is caused by elevation of intraocular pressure or it is an anatomic variant which is more vulnerable to glaucomatous damage. In this study, we compared the area of peripapillary atrophy of normal and glaucomatous eye in asymmetric glaucoma. The optic nerve head area was 2.65 +/- 0.54mm2 in glaucomatous eyes and 2.59 +/- 0.47mm2 in control eyes(p=0.53). The peripapillary atrophy area was 1.13 +/- 0.86mm2 in glaucomatous eyes and 0.94 +/- 0.81mm2 in control eyes(p=0.35). There was no significant difference in peripapillary atrophy area or optic nerve head area between glaucomatous eyes and normal eyes. Our results suggest that peripapillary atrophy may not be caused by the intraocular pressure elevation.
Atrophy* ; Glaucoma* ; Intraocular Pressure ; Ocular Hypertension ; Optic Disk

PURPOSE: The Swedish Interactive Thresholding Algorithm (SITA) strategies is a new diagnostic tool of Humphrey automatic perimetry and has been reported to reduce testing time without loss of useful diagnostic information. To test the usefulness of this new diagnostic method, we compared the SITA and full threshold diagnostic method, which had been used previously. METHODS: Forty six patients (46 eyes) who were followed up for glucoma or ocular hypertension were in this study. Autoperimetry was performed using both SITA and full threshold strategies. RESULTS: The SITA showed shorter testing time (7.74+/-1.25 min) than the full threshold (14.4+2.43 min). There were significant differences between the full threshold MD (-8.06+8.11 dB) and SITA MD (-7.45 +/-8.32 dB), as well as full threshold PSD (4.47+/-2.50 dB) and SITA PSD (3.67+/-2.56 dB), when compared with data of greater than -12 dB MD respectively(p<0.05). Two cases showed changed diagnosis in GHT. CONCLUSIONS: SITA is a good test method with short test time. However, changing from full threshold to the SITA method should be reconsidered due to variation in the amount of field defect depending on the damage progression and the possibility of changes in diagnosis.
Diagnosis ; Glaucoma* ; Humans ; Ocular Hypertension ; Visual Field Tests